Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation

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Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation. / Münscher, Adrian; Sehner, Susanne; Taleh, Jegane; Tribius, Silke; Möckelmann, Nicolaus; Böttcher, Arne; Gulati, Amit; Dalchow, Carsten; Clauditz, Till; Knecht, Rainald.

in: EUR ARCH OTO-RHINO-L, Jahrgang 272, Nr. 7, 07.2015, S. 1769-75.

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@article{8a564deedc0d4f0cb2e5fde60f986310,
title = "Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation",
abstract = "We discuss the clinical effectiveness and predictive value of routine panendoscopy for surveillance and follow-up of head and neck squamous cell carcinoma (HNSCC). Retrospective comparative study. Department of Otolaryngology-Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Two hundred and four HNSCC patients (follow-up between 2004 and 2007) were retrospectively evaluated. During follow-up, panendoscopy was performed routinely once a year. To avoid unnecessary procedures, we evaluated the value of radiological and clinical parameters in follow-up. On comparing normal-computerized tomography (CT) vs. abnormal CT results, a 13-fold higher frequency of recurrence (odds ratio 12.74; 95% CI 4.22, 38.48; p < 0.001) was found. Additionally, patient medical history, clinical investigation, and recurrence pattern were significant parameters when detecting a possible recurrence. Panendoscopy could have been avoided in 40% of patients with HNSCC (173/432). A follow-up schedule avoiding routine panendoscopy in HNSCC follow-up when the combination of diagnostic parameters is satisfactory does not influence the sensitivity or specificity of the test.",
keywords = "Aged, Carcinoma, Squamous Cell, Disease Management, Endoscopy, Female, Follow-Up Studies, Germany, Head and Neck Neoplasms, Humans, Incidence, Male, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Positron-Emission Tomography, Predictive Value of Tests, Prognosis, Retrospective Studies, Sensitivity and Specificity, Tomography, X-Ray Computed",
author = "Adrian M{\"u}nscher and Susanne Sehner and Jegane Taleh and Silke Tribius and Nicolaus M{\"o}ckelmann and Arne B{\"o}ttcher and Amit Gulati and Carsten Dalchow and Till Clauditz and Rainald Knecht",
year = "2015",
month = jul,
doi = "10.1007/s00405-014-3125-0",
language = "English",
volume = "272",
pages = "1769--75",
journal = "EUR ARCH OTO-RHINO-L",
issn = "0937-4477",
publisher = "Springer",
number = "7",

}

RIS

TY - JOUR

T1 - Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation

AU - Münscher, Adrian

AU - Sehner, Susanne

AU - Taleh, Jegane

AU - Tribius, Silke

AU - Möckelmann, Nicolaus

AU - Böttcher, Arne

AU - Gulati, Amit

AU - Dalchow, Carsten

AU - Clauditz, Till

AU - Knecht, Rainald

PY - 2015/7

Y1 - 2015/7

N2 - We discuss the clinical effectiveness and predictive value of routine panendoscopy for surveillance and follow-up of head and neck squamous cell carcinoma (HNSCC). Retrospective comparative study. Department of Otolaryngology-Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Two hundred and four HNSCC patients (follow-up between 2004 and 2007) were retrospectively evaluated. During follow-up, panendoscopy was performed routinely once a year. To avoid unnecessary procedures, we evaluated the value of radiological and clinical parameters in follow-up. On comparing normal-computerized tomography (CT) vs. abnormal CT results, a 13-fold higher frequency of recurrence (odds ratio 12.74; 95% CI 4.22, 38.48; p < 0.001) was found. Additionally, patient medical history, clinical investigation, and recurrence pattern were significant parameters when detecting a possible recurrence. Panendoscopy could have been avoided in 40% of patients with HNSCC (173/432). A follow-up schedule avoiding routine panendoscopy in HNSCC follow-up when the combination of diagnostic parameters is satisfactory does not influence the sensitivity or specificity of the test.

AB - We discuss the clinical effectiveness and predictive value of routine panendoscopy for surveillance and follow-up of head and neck squamous cell carcinoma (HNSCC). Retrospective comparative study. Department of Otolaryngology-Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Two hundred and four HNSCC patients (follow-up between 2004 and 2007) were retrospectively evaluated. During follow-up, panendoscopy was performed routinely once a year. To avoid unnecessary procedures, we evaluated the value of radiological and clinical parameters in follow-up. On comparing normal-computerized tomography (CT) vs. abnormal CT results, a 13-fold higher frequency of recurrence (odds ratio 12.74; 95% CI 4.22, 38.48; p < 0.001) was found. Additionally, patient medical history, clinical investigation, and recurrence pattern were significant parameters when detecting a possible recurrence. Panendoscopy could have been avoided in 40% of patients with HNSCC (173/432). A follow-up schedule avoiding routine panendoscopy in HNSCC follow-up when the combination of diagnostic parameters is satisfactory does not influence the sensitivity or specificity of the test.

KW - Aged

KW - Carcinoma, Squamous Cell

KW - Disease Management

KW - Endoscopy

KW - Female

KW - Follow-Up Studies

KW - Germany

KW - Head and Neck Neoplasms

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Neoplasm Recurrence, Local

KW - Neoplasm Staging

KW - Positron-Emission Tomography

KW - Predictive Value of Tests

KW - Prognosis

KW - Retrospective Studies

KW - Sensitivity and Specificity

KW - Tomography, X-Ray Computed

U2 - 10.1007/s00405-014-3125-0

DO - 10.1007/s00405-014-3125-0

M3 - SCORING: Journal article

C2 - 24906843

VL - 272

SP - 1769

EP - 1775

JO - EUR ARCH OTO-RHINO-L

JF - EUR ARCH OTO-RHINO-L

SN - 0937-4477

IS - 7

ER -