PortalPublikationenRole of mTOR Signaling for Tubular Function and Disease

Role of mTOR Signaling for Tubular Function and Disease

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Role of mTOR Signaling for Tubular Function and Disease. / Grahammer, Florian; Huber, Tobias B; Artunc, Ferruh.

in: PHYSIOLOGY, Jahrgang 36, Nr. 6, 01.11.2021, S. 350-358.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Grahammer, F, Huber, TB & Artunc, F 2021, 'Role of mTOR Signaling for Tubular Function and Disease', PHYSIOLOGY, Jg. 36, Nr. 6, S. 350-358. https://doi.org/10.1152/physiol.00021.2021

APA

Grahammer, F., Huber, T. B., & Artunc, F. (2021). Role of mTOR Signaling for Tubular Function and Disease. PHYSIOLOGY, 36(6), 350-358. https://doi.org/10.1152/physiol.00021.2021

Vancouver

Grahammer F, Huber TB, Artunc F. Role of mTOR Signaling for Tubular Function and Disease. PHYSIOLOGY. 2021 Nov 1;36(6):350-358. https://doi.org/10.1152/physiol.00021.2021

Bibtex

@article{4d8bdd4e51e3474e8013b8127193821d,
title = "Role of mTOR Signaling for Tubular Function and Disease",
abstract = "The mechanistic target of rapamycin (mTOR) forms two distinct intracellular multiprotein complexes that control a multitude of intracellular processes linked to metabolism, proliferation, actin cytoskeleton, and survival. Recent studies have identified the importance of these complexes for transport regulation of ions and nutrients along the entire nephron. First reports could link altered activity of these complexes to certain disease entities, i.e. diabetic nephropathy, acute kidney injury or hyperkalemia.",
keywords = "Humans, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Multiprotein Complexes, Sirolimus, TOR Serine-Threonine Kinases",
author = "Florian Grahammer and Huber, {Tobias B} and Ferruh Artunc",
year = "2021",
month = nov,
day = "1",
doi = "10.1152/physiol.00021.2021",
language = "English",
volume = "36",
pages = "350--358",
journal = "PHYSIOLOGY",
issn = "1548-9213",
publisher = "American Physiological Society",
number = "6",

}

RIS

TY - JOUR

T1 - Role of mTOR Signaling for Tubular Function and Disease

AU - Grahammer, Florian

AU - Huber, Tobias B

AU - Artunc, Ferruh

PY - 2021/11/1

Y1 - 2021/11/1

N2 - The mechanistic target of rapamycin (mTOR) forms two distinct intracellular multiprotein complexes that control a multitude of intracellular processes linked to metabolism, proliferation, actin cytoskeleton, and survival. Recent studies have identified the importance of these complexes for transport regulation of ions and nutrients along the entire nephron. First reports could link altered activity of these complexes to certain disease entities, i.e. diabetic nephropathy, acute kidney injury or hyperkalemia.

AB - The mechanistic target of rapamycin (mTOR) forms two distinct intracellular multiprotein complexes that control a multitude of intracellular processes linked to metabolism, proliferation, actin cytoskeleton, and survival. Recent studies have identified the importance of these complexes for transport regulation of ions and nutrients along the entire nephron. First reports could link altered activity of these complexes to certain disease entities, i.e. diabetic nephropathy, acute kidney injury or hyperkalemia.

KW - Humans

KW - Mechanistic Target of Rapamycin Complex 1

KW - Mechanistic Target of Rapamycin Complex 2

KW - Multiprotein Complexes

KW - Sirolimus

KW - TOR Serine-Threonine Kinases

U2 - 10.1152/physiol.00021.2021

DO - 10.1152/physiol.00021.2021

M3 - SCORING: Review article

C2 - 34514872

VL - 36

SP - 350

EP - 358

JO - PHYSIOLOGY

JF - PHYSIOLOGY

SN - 1548-9213

IS - 6

ER -