Rituximab in adult patients with immunosuppressive-dependent minimal change disease.
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Rituximab in adult patients with immunosuppressive-dependent minimal change disease. / Hoxha, Elion; Stahl, Rolf A.K.; Harendza, Sigrid.
in: CLIN NEPHROL, Jahrgang 76, Nr. 2, 2, 2011, S. 151-158.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Rituximab in adult patients with immunosuppressive-dependent minimal change disease.
AU - Hoxha, Elion
AU - Stahl, Rolf A.K.
AU - Harendza, Sigrid
PY - 2011
Y1 - 2011
N2 - Minimal change disease (MCD) is one of the leading causes of nephrotic syndrome. Steroid therapy is effective in achieving remission, but relapses, steroid dependence, and steroid resistance are therapeutic challenges. The use of second-line agents such as cyclophosphamide is associated with toxicity and adverse effects. Therefore, we studied the effect of rituximab (RTX) on proteinuria in adult patients with immunosuppressive (IS)-dependent MCD.
AB - Minimal change disease (MCD) is one of the leading causes of nephrotic syndrome. Steroid therapy is effective in achieving remission, but relapses, steroid dependence, and steroid resistance are therapeutic challenges. The use of second-line agents such as cyclophosphamide is associated with toxicity and adverse effects. Therefore, we studied the effect of rituximab (RTX) on proteinuria in adult patients with immunosuppressive (IS)-dependent MCD.
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Prospective Studies
KW - Treatment Outcome
KW - Recurrence
KW - Remission Induction
KW - Antineoplastic Agents/therapeutic use
KW - Immunosuppressive Agents/therapeutic use
KW - Antibodies, Monoclonal, Murine-Derived/therapeutic use
KW - Nephrosis, Lipoid/drug therapy/immunology
KW - Nephrotic Syndrome/drug therapy
KW - Proteinuria/drug therapy
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Prospective Studies
KW - Treatment Outcome
KW - Recurrence
KW - Remission Induction
KW - Antineoplastic Agents/therapeutic use
KW - Immunosuppressive Agents/therapeutic use
KW - Antibodies, Monoclonal, Murine-Derived/therapeutic use
KW - Nephrosis, Lipoid/drug therapy/immunology
KW - Nephrotic Syndrome/drug therapy
KW - Proteinuria/drug therapy
M3 - SCORING: Journal article
VL - 76
SP - 151
EP - 158
JO - CLIN NEPHROL
JF - CLIN NEPHROL
SN - 0301-0430
IS - 2
M1 - 2
ER -