PortalPublikationenReducing Hematologic Toxicity With Short Course Postexposure...

Reducing Hematologic Toxicity With Short Course Postexposure Prophylaxis With Zidovudine for HIV-1 Exposed Infants With Low Transmission Risk

  • Thi Thanh Truc Nguyen
  • Robin Kobbe
  • Ulf Schulze-Sturm
  • Martin Blohm
  • Bettina Hollwitz
  • Sandra Hertling
  • Christina Becker
  • Prasad Thomas Oommen
  • Hans-Jürgen Laws
  • Franca Martignoni
  • Björn-Erik Ole Jensen
  • Karen Olah
  • Susanne Schmidtke
  • Benno Kreuels
  • Malte Kohns Vasconcelos
  • Jennifer Neubert

Beteiligte Einrichtungen

Abstract

Using retrospectively collected data from 383 infants born to HIV-1-infected mothers receiving antiretroviral therapy, we compared transmission rates and hematologic toxicity between infants receiving 2-week (short course) versus longer duration zidovudine postexposure prophylaxis. Short course resulted in lower hematologic toxicity without evidence of increased vertical transmission risk.

Bibliografische Daten

OriginalspracheEnglisch
ISSN0891-3668
DOIs
StatusVeröffentlicht - 07.2019
PubMed 31033907