PortalPublikationenProtein intake in infancy and carotid intima media thickness...

Protein intake in infancy and carotid intima media thickness at 5 years--a secondary analysis from a randomized trial

Standard

Protein intake in infancy and carotid intima media thickness at 5 years--a secondary analysis from a randomized trial. / Gruszfeld, Dariusz; Weber, Martina; Nowakowska-Rysz, Monika; Janas, Roman; Kozlik-Feldmann, Rainer; Xhonneux, Annick; Carlier, Clotilde; Riva, Enrica; Verduci, Elvira; Closa-Monasterolo, Ricardo; Escribano, Joaquin; Dobrzanska, Anna; Koletzko, Berthold; European Childhood Obesity Study Group.

in: ANN NUTR METAB, Jahrgang 66, Nr. 1, 2015, S. 51-59.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Gruszfeld, D, Weber, M, Nowakowska-Rysz, M, Janas, R, Kozlik-Feldmann, R, Xhonneux, A, Carlier, C, Riva, E, Verduci, E, Closa-Monasterolo, R, Escribano, J, Dobrzanska, A, Koletzko, B & European Childhood Obesity Study Group 2015, 'Protein intake in infancy and carotid intima media thickness at 5 years--a secondary analysis from a randomized trial', ANN NUTR METAB, Jg. 66, Nr. 1, S. 51-59. https://doi.org/10.1159/000369980

APA

Gruszfeld, D., Weber, M., Nowakowska-Rysz, M., Janas, R., Kozlik-Feldmann, R., Xhonneux, A., Carlier, C., Riva, E., Verduci, E., Closa-Monasterolo, R., Escribano, J., Dobrzanska, A., Koletzko, B., & European Childhood Obesity Study Group (2015). Protein intake in infancy and carotid intima media thickness at 5 years--a secondary analysis from a randomized trial. ANN NUTR METAB, 66(1), 51-59. https://doi.org/10.1159/000369980

Vancouver

Gruszfeld D, Weber M, Nowakowska-Rysz M, Janas R, Kozlik-Feldmann R, Xhonneux A et al. Protein intake in infancy and carotid intima media thickness at 5 years--a secondary analysis from a randomized trial. ANN NUTR METAB. 2015;66(1):51-59. https://doi.org/10.1159/000369980

Bibtex

@article{559d5ae54ea84dd1a9a7b525f891472c,
title = "Protein intake in infancy and carotid intima media thickness at 5 years--a secondary analysis from a randomized trial",
abstract = "BACKGROUND: Nutrition in childhood has an influence on the cardiovascular function later on in life. European Childhood Obesity Project is a multicenter, randomized clinical intervention trial examining the effect of early protein intake on later health outcomes, particularly adiposity and related disorders. The aim of the study was to examine the effect of nutritional intervention--different protein intake in infancy on carotid intima-media thickness (cIMT) at 5 years. The association of cardiovascular risk factors with cIMT was also assessed.METHODS: Healthy term formula-fed infants in five European countries were enrolled either to the higher (HP) or to the lower (LP) protein group. Observational group consisted of breastfed infants. Plasma insulin, glucose, lipid profile, IGF-1, apolipoprotein A1 and B were measured as well as anthropometric parameters of parents and a child, blood pressure and physical activity.RESULTS: No difference in cIMT between HP and LP group was observed. Insulin, HOMA-IR index and total IGF-1 were positively associated with cIMT but after adjustment for confounders only an inverse association between ApoA1 and positive between ApoB/ApoA1 and cIMT were significant.CONCLUSION: High versus low protein intake in infancy does not influence cIMT at 5 years. cIMT in healthy children at 5 years is associated with their apolipoprotein profile.",
keywords = "Apolipoprotein A-I/blood, Apolipoprotein B-100/blood, Blood Glucose, Blood Pressure, Body Mass Index, Breast Feeding, Cardiovascular Diseases/pathology, Carotid Intima-Media Thickness/statistics & numerical data, Child, Preschool, Dietary Proteins/administration & dosage, Europe, Female, Follow-Up Studies, Humans, Infant, Infant Formula/administration & dosage, Infant Nutritional Physiological Phenomena, Infant, Newborn, Insulin/blood, Insulin-Like Growth Factor I/analysis, Lipids/blood, Male, Motor Activity, Risk Factors",
author = "Dariusz Gruszfeld and Martina Weber and Monika Nowakowska-Rysz and Roman Janas and Rainer Kozlik-Feldmann and Annick Xhonneux and Clotilde Carlier and Enrica Riva and Elvira Verduci and Ricardo Closa-Monasterolo and Joaquin Escribano and Anna Dobrzanska and Berthold Koletzko and {European Childhood Obesity Study Group}",
note = "{\textcopyright} 2015 S. Karger AG, Basel.",
year = "2015",
doi = "10.1159/000369980",
language = "English",
volume = "66",
pages = "51--59",
journal = "ANN NUTR METAB",
issn = "0250-6807",
publisher = "S. Karger AG",
number = "1",

}

RIS

TY - JOUR

T1 - Protein intake in infancy and carotid intima media thickness at 5 years--a secondary analysis from a randomized trial

AU - Gruszfeld, Dariusz

AU - Weber, Martina

AU - Nowakowska-Rysz, Monika

AU - Janas, Roman

AU - Kozlik-Feldmann, Rainer

AU - Xhonneux, Annick

AU - Carlier, Clotilde

AU - Riva, Enrica

AU - Verduci, Elvira

AU - Closa-Monasterolo, Ricardo

AU - Escribano, Joaquin

AU - Dobrzanska, Anna

AU - Koletzko, Berthold

AU - European Childhood Obesity Study Group

N1 - © 2015 S. Karger AG, Basel.

PY - 2015

Y1 - 2015

N2 - BACKGROUND: Nutrition in childhood has an influence on the cardiovascular function later on in life. European Childhood Obesity Project is a multicenter, randomized clinical intervention trial examining the effect of early protein intake on later health outcomes, particularly adiposity and related disorders. The aim of the study was to examine the effect of nutritional intervention--different protein intake in infancy on carotid intima-media thickness (cIMT) at 5 years. The association of cardiovascular risk factors with cIMT was also assessed.METHODS: Healthy term formula-fed infants in five European countries were enrolled either to the higher (HP) or to the lower (LP) protein group. Observational group consisted of breastfed infants. Plasma insulin, glucose, lipid profile, IGF-1, apolipoprotein A1 and B were measured as well as anthropometric parameters of parents and a child, blood pressure and physical activity.RESULTS: No difference in cIMT between HP and LP group was observed. Insulin, HOMA-IR index and total IGF-1 were positively associated with cIMT but after adjustment for confounders only an inverse association between ApoA1 and positive between ApoB/ApoA1 and cIMT were significant.CONCLUSION: High versus low protein intake in infancy does not influence cIMT at 5 years. cIMT in healthy children at 5 years is associated with their apolipoprotein profile.

AB - BACKGROUND: Nutrition in childhood has an influence on the cardiovascular function later on in life. European Childhood Obesity Project is a multicenter, randomized clinical intervention trial examining the effect of early protein intake on later health outcomes, particularly adiposity and related disorders. The aim of the study was to examine the effect of nutritional intervention--different protein intake in infancy on carotid intima-media thickness (cIMT) at 5 years. The association of cardiovascular risk factors with cIMT was also assessed.METHODS: Healthy term formula-fed infants in five European countries were enrolled either to the higher (HP) or to the lower (LP) protein group. Observational group consisted of breastfed infants. Plasma insulin, glucose, lipid profile, IGF-1, apolipoprotein A1 and B were measured as well as anthropometric parameters of parents and a child, blood pressure and physical activity.RESULTS: No difference in cIMT between HP and LP group was observed. Insulin, HOMA-IR index and total IGF-1 were positively associated with cIMT but after adjustment for confounders only an inverse association between ApoA1 and positive between ApoB/ApoA1 and cIMT were significant.CONCLUSION: High versus low protein intake in infancy does not influence cIMT at 5 years. cIMT in healthy children at 5 years is associated with their apolipoprotein profile.

KW - Apolipoprotein A-I/blood

KW - Apolipoprotein B-100/blood

KW - Blood Glucose

KW - Blood Pressure

KW - Body Mass Index

KW - Breast Feeding

KW - Cardiovascular Diseases/pathology

KW - Carotid Intima-Media Thickness/statistics & numerical data

KW - Child, Preschool

KW - Dietary Proteins/administration & dosage

KW - Europe

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Infant

KW - Infant Formula/administration & dosage

KW - Infant Nutritional Physiological Phenomena

KW - Infant, Newborn

KW - Insulin/blood

KW - Insulin-Like Growth Factor I/analysis

KW - Lipids/blood

KW - Male

KW - Motor Activity

KW - Risk Factors

U2 - 10.1159/000369980

DO - 10.1159/000369980

M3 - SCORING: Journal article

C2 - 25572773

VL - 66

SP - 51

EP - 59

JO - ANN NUTR METAB

JF - ANN NUTR METAB

SN - 0250-6807

IS - 1

ER -