Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes

Philipp Bergschmidt; Rainer Bader; Dirk Ganzer; Christian Hauzeur; Christoph H Lohmann; Alexander Krüger; Wolfgang Ruether; Domenico Tigani; Nicola Rani; José Luis Esteve; Fernando Lopez Prats; Claudio Zorzi; Vincenzo Madonna; Stefano Rigotti; Francesco Benazzo; Stefano Marco Paolo Rossi; Wolfram Mittelmeier

doi:10.1016/j.knee.2015.02.003

Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes

Standard

Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes. / Bergschmidt, Philipp; Bader, Rainer; Ganzer, Dirk; Hauzeur, Christian; Lohmann, Christoph H; Krüger, Alexander; Ruether, Wolfgang; Tigani, Domenico; Rani, Nicola; Esteve, José Luis; Prats, Fernando Lopez; Zorzi, Claudio; Madonna, Vincenzo; Rigotti, Stefano; Benazzo, Francesco; Rossi, Stefano Marco Paolo; Mittelmeier, Wolfram.

in: KNEE, Jahrgang 22, Nr. 3, 06.2015, S. 186-91.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Bergschmidt, P, Bader, R, Ganzer, D, Hauzeur, C, Lohmann, CH, Krüger, A, Ruether, W, Tigani, D, Rani, N, Esteve, JL, Prats, FL, Zorzi, C, Madonna, V, Rigotti, S, Benazzo, F, Rossi, SMP & Mittelmeier, W 2015, 'Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes', KNEE, Jg. 22, Nr. 3, S. 186-91. https://doi.org/10.1016/j.knee.2015.02.003

APA

Bergschmidt, P., Bader, R., Ganzer, D., Hauzeur, C., Lohmann, C. H., Krüger, A., Ruether, W., Tigani, D., Rani, N., Esteve, J. L., Prats, F. L., Zorzi, C., Madonna, V., Rigotti, S., Benazzo, F., Rossi, S. M. P., & Mittelmeier, W. (2015). Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes. KNEE, 22(3), 186-91. https://doi.org/10.1016/j.knee.2015.02.003

Vancouver

Bergschmidt P, Bader R, Ganzer D, Hauzeur C, Lohmann CH, Krüger A et al. Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes. KNEE. 2015 Jun;22(3):186-91. https://doi.org/10.1016/j.knee.2015.02.003

Bibtex

@article{8878953747934ddca839274a0ea4ce39,

title = "Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes",

abstract = "BACKGROUND: Enhanced wear resistance of ceramics in general and improved mechanical characteristics of composite ceramics in terms of strength and resistance meet the demands for application in TKA. The aim of this prospective international multi-centre study was to evaluate the 5-year clinical and radiological outcomes of an unconstrained TKA with a composite ceramic femoral component.METHODS: A total of 107 patients (109 knees) underwent TKA with the MULTIGEN-PLUS Ceramic Knee at seven centres in three European countries. Clinical and radiological assessments were performed preoperatively and postoperatively at 3, 12, 24 and 60 months, using HSS, WOMAC, SF-36 and standardised radiographs.RESULTS: Mean HSS and WOMAC increased significantly from 55.1±11.5 (21-83) and 48.1±16.6 (3-90) preoperatively to 85.6±9.6 (49-98) and 73.3±20.4 (17-100) at 60 months. Mean SF-36 showed significant improvements in patients' quality of life (49.1±17.6 (12-96) preoperatively versus 67.7±23.1 (12-100) at 60 months). Non-progressive radiolucent lines (<1 mm) were observed around the femoral component in four cases. Neither implant migration nor loosening were registered. Kaplan-Meier survivorship was 96.0% at 60 months (92.1-100%, CI 95%).CONCLUSIONS: Five-year implant survival rate of the ceramic knee is comparable to other metallic and ceramic unconstrained TKA systems. Although the assessment of long-term implant survivorship is still pending, the ceramic implants represent a promising solution for patients with allergies against metallic components and furthermore for the general osteoarthritis population due to enhanced wear resistance.",

author = "Philipp Bergschmidt and Rainer Bader and Dirk Ganzer and Christian Hauzeur and Lohmann, {Christoph H} and Alexander Kr{\"u}ger and Wolfgang Ruether and Domenico Tigani and Nicola Rani and Esteve, {Jos{\'e} Luis} and Prats, {Fernando Lopez} and Claudio Zorzi and Vincenzo Madonna and Stefano Rigotti and Francesco Benazzo and Rossi, {Stefano Marco Paolo} and Wolfram Mittelmeier",

year = "2015",

month = jun,

doi = "10.1016/j.knee.2015.02.003",

language = "English",

volume = "22",

pages = "186--91",

journal = "KNEE",

issn = "0968-0160",

publisher = "Elsevier",

number = "3",

}

RIS

TY - JOUR

T1 - Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes

AU - Bergschmidt, Philipp

AU - Bader, Rainer

AU - Ganzer, Dirk

AU - Hauzeur, Christian

AU - Lohmann, Christoph H

AU - Krüger, Alexander

AU - Ruether, Wolfgang

AU - Tigani, Domenico

AU - Rani, Nicola

AU - Esteve, José Luis

AU - Prats, Fernando Lopez

AU - Zorzi, Claudio

AU - Madonna, Vincenzo

AU - Rigotti, Stefano

AU - Benazzo, Francesco

AU - Rossi, Stefano Marco Paolo

AU - Mittelmeier, Wolfram

PY - 2015/6

Y1 - 2015/6

N2 - BACKGROUND: Enhanced wear resistance of ceramics in general and improved mechanical characteristics of composite ceramics in terms of strength and resistance meet the demands for application in TKA. The aim of this prospective international multi-centre study was to evaluate the 5-year clinical and radiological outcomes of an unconstrained TKA with a composite ceramic femoral component.METHODS: A total of 107 patients (109 knees) underwent TKA with the MULTIGEN-PLUS Ceramic Knee at seven centres in three European countries. Clinical and radiological assessments were performed preoperatively and postoperatively at 3, 12, 24 and 60 months, using HSS, WOMAC, SF-36 and standardised radiographs.RESULTS: Mean HSS and WOMAC increased significantly from 55.1±11.5 (21-83) and 48.1±16.6 (3-90) preoperatively to 85.6±9.6 (49-98) and 73.3±20.4 (17-100) at 60 months. Mean SF-36 showed significant improvements in patients' quality of life (49.1±17.6 (12-96) preoperatively versus 67.7±23.1 (12-100) at 60 months). Non-progressive radiolucent lines (<1 mm) were observed around the femoral component in four cases. Neither implant migration nor loosening were registered. Kaplan-Meier survivorship was 96.0% at 60 months (92.1-100%, CI 95%).CONCLUSIONS: Five-year implant survival rate of the ceramic knee is comparable to other metallic and ceramic unconstrained TKA systems. Although the assessment of long-term implant survivorship is still pending, the ceramic implants represent a promising solution for patients with allergies against metallic components and furthermore for the general osteoarthritis population due to enhanced wear resistance.

AB - BACKGROUND: Enhanced wear resistance of ceramics in general and improved mechanical characteristics of composite ceramics in terms of strength and resistance meet the demands for application in TKA. The aim of this prospective international multi-centre study was to evaluate the 5-year clinical and radiological outcomes of an unconstrained TKA with a composite ceramic femoral component.METHODS: A total of 107 patients (109 knees) underwent TKA with the MULTIGEN-PLUS Ceramic Knee at seven centres in three European countries. Clinical and radiological assessments were performed preoperatively and postoperatively at 3, 12, 24 and 60 months, using HSS, WOMAC, SF-36 and standardised radiographs.RESULTS: Mean HSS and WOMAC increased significantly from 55.1±11.5 (21-83) and 48.1±16.6 (3-90) preoperatively to 85.6±9.6 (49-98) and 73.3±20.4 (17-100) at 60 months. Mean SF-36 showed significant improvements in patients' quality of life (49.1±17.6 (12-96) preoperatively versus 67.7±23.1 (12-100) at 60 months). Non-progressive radiolucent lines (<1 mm) were observed around the femoral component in four cases. Neither implant migration nor loosening were registered. Kaplan-Meier survivorship was 96.0% at 60 months (92.1-100%, CI 95%).CONCLUSIONS: Five-year implant survival rate of the ceramic knee is comparable to other metallic and ceramic unconstrained TKA systems. Although the assessment of long-term implant survivorship is still pending, the ceramic implants represent a promising solution for patients with allergies against metallic components and furthermore for the general osteoarthritis population due to enhanced wear resistance.

U2 - 10.1016/j.knee.2015.02.003

DO - 10.1016/j.knee.2015.02.003

M3 - SCORING: Journal article

C2 - 25805085

VL - 22

SP - 186

EP - 191

JO - KNEE

JF - KNEE

SN - 0968-0160

IS - 3

ER -