Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients.
Beteiligte Einrichtungen
Abstract
Minority drug-resistant HIV-1 variants, undetected by conventional genotyping, may impair the outcome of antiretroviral therapy (ART). Thus, we retrospectively analyzed the prevalence of minority drug-resistant HIV-1 variants before ART in chronically HIV-1 infected patients initiating first-line therapy and assessed the impact on clinical outcome in the prospective German Truvada cohort.
Bibliografische Daten
| Originalsprache | Deutsch |
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| Aufsatznummer | 2 |
| ISSN | 1386-6532 |
| Status | Veröffentlicht - 2011 |
| pubmed | 21056001 |
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