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Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments

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Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments. / Chen, Chen; Klämpfl, Florian; Knipfer, Christian; Riemann, Max; Kanawade, Rajesh; Stelzle, Florian; Schmidt, Michael.

in: BIOMED OPT EXPRESS, Jahrgang 5, Nr. 9, 01.09.2014, S. 3140-9.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Chen, C, Klämpfl, F, Knipfer, C, Riemann, M, Kanawade, R, Stelzle, F & Schmidt, M 2014, 'Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments', BIOMED OPT EXPRESS, Jg. 5, Nr. 9, S. 3140-9. https://doi.org/10.1364/BOE.5.003140

APA

Chen, C., Klämpfl, F., Knipfer, C., Riemann, M., Kanawade, R., Stelzle, F., & Schmidt, M. (2014). Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments. BIOMED OPT EXPRESS, 5(9), 3140-9. https://doi.org/10.1364/BOE.5.003140

Vancouver

Chen C, Klämpfl F, Knipfer C, Riemann M, Kanawade R, Stelzle F et al. Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments. BIOMED OPT EXPRESS. 2014 Sep 1;5(9):3140-9. https://doi.org/10.1364/BOE.5.003140

Bibtex

@article{63ae0a1e0b5141e8913eadd4f278e0cd,
title = "Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments",
abstract = "A popular alternative of preparing multilayer or microfluidic chip based phantoms could have helped to simulate the subsurface vascular network, but brought inevitable problems. In this work, we describe the preparation method of a single layer skin equivalent tissue phantom containing interior vessel channels, which mimick the superficial microvascular structure. The fabrication method does not disturb the optical properties of the turbiding matrix material. The diameter of the channels reaches a value of 50 μm. The size, as well as the geometry of the generated vessel structures are investigated by using the SD-OCT system. Our preliminary results confirm that fabrication of such a phantom is achievable and reproducible. Prospectively, this phantom is used to calibrate the optical angiographic imaging approaches.",
keywords = "Journal Article",
author = "Chen Chen and Florian Kl{\"a}mpfl and Christian Knipfer and Max Riemann and Rajesh Kanawade and Florian Stelzle and Michael Schmidt",
year = "2014",
month = sep,
day = "1",
doi = "10.1364/BOE.5.003140",
language = "English",
volume = "5",
pages = "3140--9",
journal = "BIOMED OPT EXPRESS",
issn = "2156-7085",
publisher = "The Optical Society",
number = "9",

}

RIS

TY - JOUR

T1 - Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments

AU - Chen, Chen

AU - Klämpfl, Florian

AU - Knipfer, Christian

AU - Riemann, Max

AU - Kanawade, Rajesh

AU - Stelzle, Florian

AU - Schmidt, Michael

PY - 2014/9/1

Y1 - 2014/9/1

N2 - A popular alternative of preparing multilayer or microfluidic chip based phantoms could have helped to simulate the subsurface vascular network, but brought inevitable problems. In this work, we describe the preparation method of a single layer skin equivalent tissue phantom containing interior vessel channels, which mimick the superficial microvascular structure. The fabrication method does not disturb the optical properties of the turbiding matrix material. The diameter of the channels reaches a value of 50 μm. The size, as well as the geometry of the generated vessel structures are investigated by using the SD-OCT system. Our preliminary results confirm that fabrication of such a phantom is achievable and reproducible. Prospectively, this phantom is used to calibrate the optical angiographic imaging approaches.

AB - A popular alternative of preparing multilayer or microfluidic chip based phantoms could have helped to simulate the subsurface vascular network, but brought inevitable problems. In this work, we describe the preparation method of a single layer skin equivalent tissue phantom containing interior vessel channels, which mimick the superficial microvascular structure. The fabrication method does not disturb the optical properties of the turbiding matrix material. The diameter of the channels reaches a value of 50 μm. The size, as well as the geometry of the generated vessel structures are investigated by using the SD-OCT system. Our preliminary results confirm that fabrication of such a phantom is achievable and reproducible. Prospectively, this phantom is used to calibrate the optical angiographic imaging approaches.

KW - Journal Article

U2 - 10.1364/BOE.5.003140

DO - 10.1364/BOE.5.003140

M3 - SCORING: Journal article

C2 - 25401027

VL - 5

SP - 3140

EP - 3149

JO - BIOMED OPT EXPRESS

JF - BIOMED OPT EXPRESS

SN - 2156-7085

IS - 9

ER -