Prediction of Changes in Negative Affect During the COVID-19 Pandemic by Experimental Fear Conditioning and Generalization Measures
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Prediction of Changes in Negative Affect During the COVID-19 Pandemic by Experimental Fear Conditioning and Generalization Measures. / Imholze, Celina; Hutterer, Katharina; Gall, Dominik; Dannlowski, Udo; Domschke, Katharina; Leehr, Elisabeth J; Lonsdorf, Tina Barbara; Lueken, Ulrike; Reif, Andreas; Rosenkranz, Karoline Sophia; Schiele, Miriam A.; Zwanzger, Peter; Pauli, Paul; Gamer, Matthias.
in: Z PSYCHOL, Jahrgang 231, Nr. 2, 05.2023, S. 137-148.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Prediction of Changes in Negative Affect During the COVID-19 Pandemic by Experimental Fear Conditioning and Generalization Measures
AU - Imholze, Celina
AU - Hutterer, Katharina
AU - Gall, Dominik
AU - Dannlowski, Udo
AU - Domschke, Katharina
AU - Leehr, Elisabeth J
AU - Lonsdorf, Tina Barbara
AU - Lueken, Ulrike
AU - Reif, Andreas
AU - Rosenkranz, Karoline Sophia
AU - Schiele, Miriam A.
AU - Zwanzger, Peter
AU - Pauli, Paul
AU - Gamer, Matthias
PY - 2023/5
Y1 - 2023/5
N2 - Adverse experiences interact with individual vulnerability in the etiology of mental disorders, but due to the paucity of longitudinalstudies, their precise interplay remains unclear. Here, we investigated how individual differences in threat responsiveness modulated ad-justments in negative affect during the COVID-19 pandemic. Participants (N= 441) underwent a fear conditioning and generalization experimentbetween 2013 and 2020 and were reassessed regarding anxiety and depression symptoms after the pandemic outbreak. Participants showedincreased levels of negative affect following pandemic onset, which were partly modulated by laboratory measures of threat responsiveness.Decreased differentiation of threat and safety signals in participants with higher prepandemic depression and anxiety scores in the laboratoryassessment were most predictive of increased symptom levels after the onset of the pandemic. However, effects were small and should bereplicated in independent samples to further characterize how individual differences in threat processing interact with adverse experiences inthe development of psychopathology.
AB - Adverse experiences interact with individual vulnerability in the etiology of mental disorders, but due to the paucity of longitudinalstudies, their precise interplay remains unclear. Here, we investigated how individual differences in threat responsiveness modulated ad-justments in negative affect during the COVID-19 pandemic. Participants (N= 441) underwent a fear conditioning and generalization experimentbetween 2013 and 2020 and were reassessed regarding anxiety and depression symptoms after the pandemic outbreak. Participants showedincreased levels of negative affect following pandemic onset, which were partly modulated by laboratory measures of threat responsiveness.Decreased differentiation of threat and safety signals in participants with higher prepandemic depression and anxiety scores in the laboratoryassessment were most predictive of increased symptom levels after the onset of the pandemic. However, effects were small and should bereplicated in independent samples to further characterize how individual differences in threat processing interact with adverse experiences inthe development of psychopathology.
U2 - 10.1027/2151-2604/a000523
DO - 10.1027/2151-2604/a000523
M3 - SCORING: Journal article
VL - 231
SP - 137
EP - 148
JO - Z PSYCHOL
JF - Z PSYCHOL
SN - 2190-8370
IS - 2
ER -