Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease
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Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease. / Schleberger, Ruben; Jularic, Mario; Salzbrunn, Tim; Hacke, Claudia; Schwarzl, Jana M; Hoffmann, Boris A; Steven, Daniel; Willems, Stephan; Lemoine, Marc D; Meyer, Christian.
in: EUR J MED RES, Jahrgang 25, Nr. 1, 4, 17.03.2020.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease
AU - Schleberger, Ruben
AU - Jularic, Mario
AU - Salzbrunn, Tim
AU - Hacke, Claudia
AU - Schwarzl, Jana M
AU - Hoffmann, Boris A
AU - Steven, Daniel
AU - Willems, Stephan
AU - Lemoine, Marc D
AU - Meyer, Christian
PY - 2020/3/17
Y1 - 2020/3/17
N2 - BACKGROUND: Catheter ablation of non-reentrant, commonly termed "idiopathic" ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). Meanwhile, the outcome of catheter ablation of these arrhythmias in patients with SHD remains unclear. This study sought to characterize the outcome of patients with and without SHD undergoing catheter ablation of non-reentrant VA.METHODS: In this single-centre study the acute and long-term outcome of 266 consecutive patients undergoing catheter ablation of non-reentrant VA was investigated. In 41.0% of patients a SHD was present (n = 109, 80.7% male, age 59.1 ± 14.7 years), 59.0% had no SHD (n = 157; 44.0% male, age 49.9 ± 16.5 years).RESULTS: Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h after the procedure) was achieved in 89.9% of patients with SHD vs. 94.3% without SHD (p = 0.238). During a mean follow-up of 34.7 ± 15.1 months a repeat catheter ablation was performed in 19.6% of patients with SHD vs. 13.0% without SHD (p = 0.179). Patients with dilated cardiomyopathy (DCM) were the most likely to require a repeat ablation procedure (32.0% of patients with DCM vs. 13.0% without SHD; p = 0.022). Periprocedural complications occurred in 5.5% of patients with SHD vs. 5.7% without SHD (p > 0.999). All complications were managed without sequelae.CONCLUSIONS: The outcome of catheter ablation of non-reentrant VA in patients with SHD appears good and is comparable to patients without SHD. A slightly higher rate of repeat ablations was observed in patients with DCM.
AB - BACKGROUND: Catheter ablation of non-reentrant, commonly termed "idiopathic" ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). Meanwhile, the outcome of catheter ablation of these arrhythmias in patients with SHD remains unclear. This study sought to characterize the outcome of patients with and without SHD undergoing catheter ablation of non-reentrant VA.METHODS: In this single-centre study the acute and long-term outcome of 266 consecutive patients undergoing catheter ablation of non-reentrant VA was investigated. In 41.0% of patients a SHD was present (n = 109, 80.7% male, age 59.1 ± 14.7 years), 59.0% had no SHD (n = 157; 44.0% male, age 49.9 ± 16.5 years).RESULTS: Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h after the procedure) was achieved in 89.9% of patients with SHD vs. 94.3% without SHD (p = 0.238). During a mean follow-up of 34.7 ± 15.1 months a repeat catheter ablation was performed in 19.6% of patients with SHD vs. 13.0% without SHD (p = 0.179). Patients with dilated cardiomyopathy (DCM) were the most likely to require a repeat ablation procedure (32.0% of patients with DCM vs. 13.0% without SHD; p = 0.022). Periprocedural complications occurred in 5.5% of patients with SHD vs. 5.7% without SHD (p > 0.999). All complications were managed without sequelae.CONCLUSIONS: The outcome of catheter ablation of non-reentrant VA in patients with SHD appears good and is comparable to patients without SHD. A slightly higher rate of repeat ablations was observed in patients with DCM.
KW - Adult
KW - Cardiomyopathy, Dilated/etiology
KW - Catheter Ablation/methods
KW - Female
KW - Heart Diseases/surgery
KW - Humans
KW - Male
KW - Middle Aged
KW - Tachycardia, Ventricular/etiology
KW - Treatment Outcome
U2 - 10.1186/s40001-020-0400-y
DO - 10.1186/s40001-020-0400-y
M3 - SCORING: Journal article
C2 - 32183887
VL - 25
JO - EUR J MED RES
JF - EUR J MED RES
SN - 0949-2321
IS - 1
M1 - 4
ER -