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Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease

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Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease. / Schleberger, Ruben; Jularic, Mario; Salzbrunn, Tim; Hacke, Claudia; Schwarzl, Jana M; Hoffmann, Boris A; Steven, Daniel; Willems, Stephan; Lemoine, Marc D; Meyer, Christian.

In: EUR J MED RES, Vol. 25, No. 1, 4, 17.03.2020.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schleberger, R, Jularic, M, Salzbrunn, T, Hacke, C, Schwarzl, JM, Hoffmann, BA, Steven, D, Willems, S, Lemoine, MD & Meyer, C 2020, 'Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease', EUR J MED RES, vol. 25, no. 1, 4. https://doi.org/10.1186/s40001-020-0400-y

APA

Schleberger, R., Jularic, M., Salzbrunn, T., Hacke, C., Schwarzl, J. M., Hoffmann, B. A., Steven, D., Willems, S., Lemoine, M. D., & Meyer, C. (2020). Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease. EUR J MED RES, 25(1), [4]. https://doi.org/10.1186/s40001-020-0400-y

Vancouver

Schleberger R, Jularic M, Salzbrunn T, Hacke C, Schwarzl JM, Hoffmann BA et al. Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease. EUR J MED RES. 2020 Mar 17;25(1). 4. https://doi.org/10.1186/s40001-020-0400-y

Bibtex

@article{48aae24cf01a4f11a0cd43a840f78787,
title = "Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease",
abstract = "BACKGROUND: Catheter ablation of non-reentrant, commonly termed {"}idiopathic{"} ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). Meanwhile, the outcome of catheter ablation of these arrhythmias in patients with SHD remains unclear. This study sought to characterize the outcome of patients with and without SHD undergoing catheter ablation of non-reentrant VA.METHODS: In this single-centre study the acute and long-term outcome of 266 consecutive patients undergoing catheter ablation of non-reentrant VA was investigated. In 41.0% of patients a SHD was present (n = 109, 80.7% male, age 59.1 ± 14.7 years), 59.0% had no SHD (n = 157; 44.0% male, age 49.9 ± 16.5 years).RESULTS: Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h after the procedure) was achieved in 89.9% of patients with SHD vs. 94.3% without SHD (p = 0.238). During a mean follow-up of 34.7 ± 15.1 months a repeat catheter ablation was performed in 19.6% of patients with SHD vs. 13.0% without SHD (p = 0.179). Patients with dilated cardiomyopathy (DCM) were the most likely to require a repeat ablation procedure (32.0% of patients with DCM vs. 13.0% without SHD; p = 0.022). Periprocedural complications occurred in 5.5% of patients with SHD vs. 5.7% without SHD (p > 0.999). All complications were managed without sequelae.CONCLUSIONS: The outcome of catheter ablation of non-reentrant VA in patients with SHD appears good and is comparable to patients without SHD. A slightly higher rate of repeat ablations was observed in patients with DCM.",
keywords = "Adult, Cardiomyopathy, Dilated/etiology, Catheter Ablation/methods, Female, Heart Diseases/surgery, Humans, Male, Middle Aged, Tachycardia, Ventricular/etiology, Treatment Outcome",
author = "Ruben Schleberger and Mario Jularic and Tim Salzbrunn and Claudia Hacke and Schwarzl, {Jana M} and Hoffmann, {Boris A} and Daniel Steven and Stephan Willems and Lemoine, {Marc D} and Christian Meyer",
year = "2020",
month = mar,
day = "17",
doi = "10.1186/s40001-020-0400-y",
language = "English",
volume = "25",
journal = "EUR J MED RES",
issn = "0949-2321",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease

AU - Schleberger, Ruben

AU - Jularic, Mario

AU - Salzbrunn, Tim

AU - Hacke, Claudia

AU - Schwarzl, Jana M

AU - Hoffmann, Boris A

AU - Steven, Daniel

AU - Willems, Stephan

AU - Lemoine, Marc D

AU - Meyer, Christian

PY - 2020/3/17

Y1 - 2020/3/17

N2 - BACKGROUND: Catheter ablation of non-reentrant, commonly termed "idiopathic" ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). Meanwhile, the outcome of catheter ablation of these arrhythmias in patients with SHD remains unclear. This study sought to characterize the outcome of patients with and without SHD undergoing catheter ablation of non-reentrant VA.METHODS: In this single-centre study the acute and long-term outcome of 266 consecutive patients undergoing catheter ablation of non-reentrant VA was investigated. In 41.0% of patients a SHD was present (n = 109, 80.7% male, age 59.1 ± 14.7 years), 59.0% had no SHD (n = 157; 44.0% male, age 49.9 ± 16.5 years).RESULTS: Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h after the procedure) was achieved in 89.9% of patients with SHD vs. 94.3% without SHD (p = 0.238). During a mean follow-up of 34.7 ± 15.1 months a repeat catheter ablation was performed in 19.6% of patients with SHD vs. 13.0% without SHD (p = 0.179). Patients with dilated cardiomyopathy (DCM) were the most likely to require a repeat ablation procedure (32.0% of patients with DCM vs. 13.0% without SHD; p = 0.022). Periprocedural complications occurred in 5.5% of patients with SHD vs. 5.7% without SHD (p > 0.999). All complications were managed without sequelae.CONCLUSIONS: The outcome of catheter ablation of non-reentrant VA in patients with SHD appears good and is comparable to patients without SHD. A slightly higher rate of repeat ablations was observed in patients with DCM.

AB - BACKGROUND: Catheter ablation of non-reentrant, commonly termed "idiopathic" ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). Meanwhile, the outcome of catheter ablation of these arrhythmias in patients with SHD remains unclear. This study sought to characterize the outcome of patients with and without SHD undergoing catheter ablation of non-reentrant VA.METHODS: In this single-centre study the acute and long-term outcome of 266 consecutive patients undergoing catheter ablation of non-reentrant VA was investigated. In 41.0% of patients a SHD was present (n = 109, 80.7% male, age 59.1 ± 14.7 years), 59.0% had no SHD (n = 157; 44.0% male, age 49.9 ± 16.5 years).RESULTS: Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h after the procedure) was achieved in 89.9% of patients with SHD vs. 94.3% without SHD (p = 0.238). During a mean follow-up of 34.7 ± 15.1 months a repeat catheter ablation was performed in 19.6% of patients with SHD vs. 13.0% without SHD (p = 0.179). Patients with dilated cardiomyopathy (DCM) were the most likely to require a repeat ablation procedure (32.0% of patients with DCM vs. 13.0% without SHD; p = 0.022). Periprocedural complications occurred in 5.5% of patients with SHD vs. 5.7% without SHD (p > 0.999). All complications were managed without sequelae.CONCLUSIONS: The outcome of catheter ablation of non-reentrant VA in patients with SHD appears good and is comparable to patients without SHD. A slightly higher rate of repeat ablations was observed in patients with DCM.

KW - Adult

KW - Cardiomyopathy, Dilated/etiology

KW - Catheter Ablation/methods

KW - Female

KW - Heart Diseases/surgery

KW - Humans

KW - Male

KW - Middle Aged

KW - Tachycardia, Ventricular/etiology

KW - Treatment Outcome

U2 - 10.1186/s40001-020-0400-y

DO - 10.1186/s40001-020-0400-y

M3 - SCORING: Journal article

C2 - 32183887

VL - 25

JO - EUR J MED RES

JF - EUR J MED RES

SN - 0949-2321

IS - 1

M1 - 4

ER -