Oscillatory entrainment of primary somatosensory cortex encodes visual control of tactile processing.
Standard
Oscillatory entrainment of primary somatosensory cortex encodes visual control of tactile processing. / Sieben, Kay; Röder, Brigitte; Hanganu-Opatz, Ileana L.
in: J NEUROSCI, Jahrgang 33, Nr. 13, 13, 2013, S. 5736-5749.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Oscillatory entrainment of primary somatosensory cortex encodes visual control of tactile processing.
AU - Sieben, Kay
AU - Röder, Brigitte
AU - Hanganu-Opatz, Ileana L
PY - 2013
Y1 - 2013
N2 - Optimal behavior relies on the successful integration of complementary information from multiple senses. The neural mechanisms underlying multisensory interactions are still poorly understood. Here, we demonstrate the critical role of neural network oscillations and direct connectivity between primary sensory cortices in visual-somatosensory interactions. Extracellular recordings from all layers of the barrel field in Brown Norway rats in vivo showed that bimodal stimulation (simultaneous light flash and whisker deflection) augmented the somatosensory-evoked response and changed the power of induced network oscillations by resetting their phase. Anatomical tracing revealed sparse direct connectivity between primary visual (V1) and somatosensory (S1) cortices. Pharmacological silencing of V1 diminished but did not abolish cross-modal effects on S1 oscillatory activity, while leaving the early enhancement of the evoked response unaffected. Thus, visual stimuli seem to impact tactile processing by modulating network oscillations in S1 via corticocortical projections and subcortical feedforward interactions.
AB - Optimal behavior relies on the successful integration of complementary information from multiple senses. The neural mechanisms underlying multisensory interactions are still poorly understood. Here, we demonstrate the critical role of neural network oscillations and direct connectivity between primary sensory cortices in visual-somatosensory interactions. Extracellular recordings from all layers of the barrel field in Brown Norway rats in vivo showed that bimodal stimulation (simultaneous light flash and whisker deflection) augmented the somatosensory-evoked response and changed the power of induced network oscillations by resetting their phase. Anatomical tracing revealed sparse direct connectivity between primary visual (V1) and somatosensory (S1) cortices. Pharmacological silencing of V1 diminished but did not abolish cross-modal effects on S1 oscillatory activity, while leaving the early enhancement of the evoked response unaffected. Thus, visual stimuli seem to impact tactile processing by modulating network oscillations in S1 via corticocortical projections and subcortical feedforward interactions.
KW - Animals
KW - Rats
KW - Mass Spectrometry
KW - Action Potentials/physiology
KW - Brain Mapping
KW - Anesthetics, Local/pharmacology
KW - Lidocaine/pharmacology
KW - Biological Clocks/physiology
KW - Physical Stimulation
KW - Touch/physiology
KW - Psychophysics
KW - Vision, Ocular/physiology
KW - Neurons/drug effects/physiology
KW - Afferent Pathways/drug effects/physiology
KW - Evoked Potentials/drug effects/physiology
KW - Reaction Time/drug effects/physiology
KW - Somatosensory Cortex/cytology/drug effects/physiology
KW - Stilbamidines/metabolism
KW - Vibrissae/innervation
KW - Animals
KW - Rats
KW - Mass Spectrometry
KW - Action Potentials/physiology
KW - Brain Mapping
KW - Anesthetics, Local/pharmacology
KW - Lidocaine/pharmacology
KW - Biological Clocks/physiology
KW - Physical Stimulation
KW - Touch/physiology
KW - Psychophysics
KW - Vision, Ocular/physiology
KW - Neurons/drug effects/physiology
KW - Afferent Pathways/drug effects/physiology
KW - Evoked Potentials/drug effects/physiology
KW - Reaction Time/drug effects/physiology
KW - Somatosensory Cortex/cytology/drug effects/physiology
KW - Stilbamidines/metabolism
KW - Vibrissae/innervation
U2 - 10.1523/JNEUROSCI.4432-12.2013
DO - 10.1523/JNEUROSCI.4432-12.2013
M3 - SCORING: Journal article
C2 - 23536087
VL - 33
SP - 5736
EP - 5749
JO - J NEUROSCI
JF - J NEUROSCI
SN - 0270-6474
IS - 13
M1 - 13
ER -
