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Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography

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Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography. / Canjau, Silvana; Todea, Carmen; Sinescu, Cosmin; Negrutiu, Meda L.; Duma, Virgil; Manescu, Adrian; Topala, Florin I.; Podoleanu, Adrian Gh.

HEAD AND NECK OPTICAL DIAGNOSTICS. Hrsg. / C Betz; BJF Wong. Band 8805 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA : SPIE-INT SOC OPTICAL ENGINEERING, 2013. (Proceedings of SPIE).

Publikationen: SCORING: Beitrag in Buch/Sammelwerk › SCORING: Beitrag in Sammelwerk › Forschung › Begutachtung

Harvard

Canjau, S, Todea, C, Sinescu, C, Negrutiu, ML, Duma, V, Manescu, A, Topala, FI & Podoleanu, AG 2013, Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography. in C Betz & BJF Wong (Hrsg.), HEAD AND NECK OPTICAL DIAGNOSTICS. Bd. 8805, Proceedings of SPIE, SPIE-INT SOC OPTICAL ENGINEERING, 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA. https://doi.org/10.1117/12.2032584

APA

Canjau, S., Todea, C., Sinescu, C., Negrutiu, M. L., Duma, V., Manescu, A., Topala, F. I., & Podoleanu, A. G. (2013). Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography. in C. Betz, & BJF. Wong (Hrsg.), HEAD AND NECK OPTICAL DIAGNOSTICS (Band 8805). (Proceedings of SPIE). SPIE-INT SOC OPTICAL ENGINEERING. https://doi.org/10.1117/12.2032584

Vancouver

Canjau S, Todea C, Sinescu C, Negrutiu ML, Duma V, Manescu A et al. Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography. in Betz C, Wong BJF, Hrsg., HEAD AND NECK OPTICAL DIAGNOSTICS. Band 8805. 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA: SPIE-INT SOC OPTICAL ENGINEERING. 2013. (Proceedings of SPIE). https://doi.org/10.1117/12.2032584

Bibtex

@inbook{8f512546ecd14beda0ef2b7d2233182e,
title = "Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography",
abstract = "The efforts aimed at early diagnosis of oral cancer should be prioritized towards developing a new screening instrument, based on optical coherence tomography (OCT), to be used directly intraorally, able to perform a fast, real time, 3D and non-invasive diagnosis of oral malignancies. The first step in this direction would be to optimize the OCT image interpretation of oral tissues. Therefore we propose plastination as a tissue preparation method that better preserves three-dimensional structure for study by new optical imaging techniques. The OCT and the synchrotron radiation computed microtomography (micro-CT) were employed for tissue sample analyze. For validating the OCT results we used the gold standard diagnostic procedure for any suspicious lesion - histopathology. This is a preliminary study of comparing features provided by OCT and Micro-CT. In the conditions of the present study, OCT proves to be a highly promising imaging modality. The use of x-ray based topographic imaging of small biological samples has been limited by the low intrinsic x-ray absorption of non-mineralized tissue and the lack of established contrast agents. Plastination can be used to enhance optical imagies of oral soft tissue samples.",
keywords = "Oral squamous cell carcinoma, minimally-invasive diagnosis, plastination, optical coherence tomography, Micro-CT",
author = "Silvana Canjau and Carmen Todea and Cosmin Sinescu and Negrutiu, {Meda L.} and Virgil Duma and Adrian Manescu and Topala, {Florin I.} and Podoleanu, {Adrian Gh.}",
note = "5th Scientific Meeting of the Head-and-Neck-Optical-Diagnostic-Society (HNODS), Munich, GERMANY, MAY 13-14, 2013",
year = "2013",
doi = "10.1117/12.2032584",
language = "English",
isbn = "978-0-8194-9813-7",
volume = "8805",
series = "Proceedings of SPIE",
publisher = "SPIE-INT SOC OPTICAL ENGINEERING",
editor = "C Betz and BJF Wong",
booktitle = "HEAD AND NECK OPTICAL DIAGNOSTICS",

}

RIS

TY - CHAP

T1 - Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography

AU - Canjau, Silvana

AU - Todea, Carmen

AU - Sinescu, Cosmin

AU - Negrutiu, Meda L.

AU - Duma, Virgil

AU - Manescu, Adrian

AU - Topala, Florin I.

AU - Podoleanu, Adrian Gh.

N1 - 5th Scientific Meeting of the Head-and-Neck-Optical-Diagnostic-Society (HNODS), Munich, GERMANY, MAY 13-14, 2013

PY - 2013

Y1 - 2013

N2 - The efforts aimed at early diagnosis of oral cancer should be prioritized towards developing a new screening instrument, based on optical coherence tomography (OCT), to be used directly intraorally, able to perform a fast, real time, 3D and non-invasive diagnosis of oral malignancies. The first step in this direction would be to optimize the OCT image interpretation of oral tissues. Therefore we propose plastination as a tissue preparation method that better preserves three-dimensional structure for study by new optical imaging techniques. The OCT and the synchrotron radiation computed microtomography (micro-CT) were employed for tissue sample analyze. For validating the OCT results we used the gold standard diagnostic procedure for any suspicious lesion - histopathology. This is a preliminary study of comparing features provided by OCT and Micro-CT. In the conditions of the present study, OCT proves to be a highly promising imaging modality. The use of x-ray based topographic imaging of small biological samples has been limited by the low intrinsic x-ray absorption of non-mineralized tissue and the lack of established contrast agents. Plastination can be used to enhance optical imagies of oral soft tissue samples.

AB - The efforts aimed at early diagnosis of oral cancer should be prioritized towards developing a new screening instrument, based on optical coherence tomography (OCT), to be used directly intraorally, able to perform a fast, real time, 3D and non-invasive diagnosis of oral malignancies. The first step in this direction would be to optimize the OCT image interpretation of oral tissues. Therefore we propose plastination as a tissue preparation method that better preserves three-dimensional structure for study by new optical imaging techniques. The OCT and the synchrotron radiation computed microtomography (micro-CT) were employed for tissue sample analyze. For validating the OCT results we used the gold standard diagnostic procedure for any suspicious lesion - histopathology. This is a preliminary study of comparing features provided by OCT and Micro-CT. In the conditions of the present study, OCT proves to be a highly promising imaging modality. The use of x-ray based topographic imaging of small biological samples has been limited by the low intrinsic x-ray absorption of non-mineralized tissue and the lack of established contrast agents. Plastination can be used to enhance optical imagies of oral soft tissue samples.

KW - Oral squamous cell carcinoma

KW - minimally-invasive diagnosis

KW - plastination

KW - optical coherence tomography

KW - Micro-CT

U2 - 10.1117/12.2032584

DO - 10.1117/12.2032584

M3 - SCORING: Contribution to collected editions/anthologies

SN - 978-0-8194-9813-7

VL - 8805

T3 - Proceedings of SPIE

BT - HEAD AND NECK OPTICAL DIAGNOSTICS

A2 - Betz, C

A2 - Wong, BJF

PB - SPIE-INT SOC OPTICAL ENGINEERING

CY - 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA

ER -