Neue Aspekte der MRT-Bildgebung zur Diagnostik der Großgefäßvaskulitiden sowie der primären Angiitis des zentralen Nervensystems

TY - JOUR

T1 - Neue Aspekte der MRT-Bildgebung zur Diagnostik der Großgefäßvaskulitiden sowie der primären Angiitis des zentralen Nervensystems

AU - Saam, Tobias

AU - Habs, M

AU - Cyran, C C

AU - Grimm, J

AU - Pfefferkorn, T

AU - Schüller, U

AU - Reiser, Maximilian F

AU - Nikolaou, Konstantin

PY - 2010/10

Y1 - 2010/10

N2 - Vasculitis is a rare disease and clinical symptoms are often unspecific. Accurate and early diagnosis is mandatory in order to prevent complications, such as loss of vision or stroke. Imaging techniques can contribute to establishing a definite diagnosis and to evaluate disease activity and the extent of the disease in various vascular regions. Conventional imaging methods, such as computed tomography (CT) and magnetic resonance (MR) angiography, as well as digital subtraction angiography allow the vessel lumen but not the vessel wall to be depicted. However, vasculitis is a disease which primarily affects the vessel wall, therefore conventional imaging modalities often fail to make a definite diagnosis. Recently black-blood high resolution MR in vivo imaging has been used to visualize cervical and intracranial vasculitis. This review article presents imaging protocols for intracranial and cervical black-blood MR imaging and clinical cases with large vessel vasculitis and vasculitis of the central nervous system. Furthermore the current literature, examples of the most common differential diagnoses of cervical and cranial arteriopathy and the potential of other imaging modalities, such as PET/CT and ultrasound will be discussed.

AB - Vasculitis is a rare disease and clinical symptoms are often unspecific. Accurate and early diagnosis is mandatory in order to prevent complications, such as loss of vision or stroke. Imaging techniques can contribute to establishing a definite diagnosis and to evaluate disease activity and the extent of the disease in various vascular regions. Conventional imaging methods, such as computed tomography (CT) and magnetic resonance (MR) angiography, as well as digital subtraction angiography allow the vessel lumen but not the vessel wall to be depicted. However, vasculitis is a disease which primarily affects the vessel wall, therefore conventional imaging modalities often fail to make a definite diagnosis. Recently black-blood high resolution MR in vivo imaging has been used to visualize cervical and intracranial vasculitis. This review article presents imaging protocols for intracranial and cervical black-blood MR imaging and clinical cases with large vessel vasculitis and vasculitis of the central nervous system. Furthermore the current literature, examples of the most common differential diagnoses of cervical and cranial arteriopathy and the potential of other imaging modalities, such as PET/CT and ultrasound will be discussed.

KW - Adult

KW - Aged

KW - Angiography, Digital Subtraction

KW - Aortic Diseases

KW - Arterial Occlusive Diseases

KW - Arteries

KW - Autoimmune Diseases

KW - Female

KW - Giant Cell Arteritis

KW - Humans

KW - Image Enhancement

KW - Image Processing, Computer-Assisted

KW - Imaging, Three-Dimensional

KW - Magnetic Resonance Angiography

KW - Male

KW - Middle Aged

KW - Positron-Emission Tomography

KW - Sensitivity and Specificity

KW - Systemic Vasculitis

KW - Takayasu Arteritis

KW - Tomography, X-Ray Computed

KW - Vasculitis, Central Nervous System

KW - Young Adult

KW - English Abstract

KW - Journal Article

U2 - 10.1007/s00117-010-2004-y

DO - 10.1007/s00117-010-2004-y

M3 - SCORING: Zeitschriftenaufsatz

C2 - 20799025

VL - 50

SP - 861

EP - 871

JO - RADIOLOGE

JF - RADIOLOGE

SN - 0033-832X

IS - 10

ER -