Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less.

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Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less. / Thomalla, Götz; Rossbach, Philipp; Rosenkranz, Michael; Siemonsen, Susanne; Krützelmann, Anna; Fiehler, Jens; Gerloff, Christian.

in: ANN NEUROL, Jahrgang 65, Nr. 6, 6, 2009, S. 724-732.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{644c2319c1b74807bd7a2fcf34ffe740,
title = "Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less.",
abstract = "OBJECTIVE: o evaluate the use of fluid-attenuated inversion recovery (FLAIR) imaging as surrogate marker of lesion age within the first 6 hours of ischemic stroke. METHODS: e analyzed FLAIR and diffusion-weighted imaging (DWI) sequences performed within 6 hours of symptom onset in 120 consecutive patients with ischemic stroke with known symptom onset. The visibility of acute ischemic lesions on FLAIR images was judged in two steps (on FLAIR alone and with knowledge of DWI) and compared with DWI. RESULTS: egative FLAIR in the case of positive DWI allocated ischemic lesions to a time window 3 hours or less with a high specificity (0.93) and a high positive predictive value (0.94), whereas sensitivity (0.48) and negative predictive value (0.43) were low. Lesion visibility on FLAIR images alone (35.6%) and with knowledge of DWI (62.5%) was lower than on DWI (97.1%). The sensitivity of FLAIR increased with increasing time from symptom onset from 27.0/50.0%",
author = "G{\"o}tz Thomalla and Philipp Rossbach and Michael Rosenkranz and Susanne Siemonsen and Anna Kr{\"u}tzelmann and Jens Fiehler and Christian Gerloff",
year = "2009",
language = "Deutsch",
volume = "65",
pages = "724--732",
journal = "ANN NEUROL",
issn = "0364-5134",
publisher = "John Wiley and Sons Inc.",
number = "6",

}

RIS

TY - JOUR

T1 - Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less.

AU - Thomalla, Götz

AU - Rossbach, Philipp

AU - Rosenkranz, Michael

AU - Siemonsen, Susanne

AU - Krützelmann, Anna

AU - Fiehler, Jens

AU - Gerloff, Christian

PY - 2009

Y1 - 2009

N2 - OBJECTIVE: o evaluate the use of fluid-attenuated inversion recovery (FLAIR) imaging as surrogate marker of lesion age within the first 6 hours of ischemic stroke. METHODS: e analyzed FLAIR and diffusion-weighted imaging (DWI) sequences performed within 6 hours of symptom onset in 120 consecutive patients with ischemic stroke with known symptom onset. The visibility of acute ischemic lesions on FLAIR images was judged in two steps (on FLAIR alone and with knowledge of DWI) and compared with DWI. RESULTS: egative FLAIR in the case of positive DWI allocated ischemic lesions to a time window 3 hours or less with a high specificity (0.93) and a high positive predictive value (0.94), whereas sensitivity (0.48) and negative predictive value (0.43) were low. Lesion visibility on FLAIR images alone (35.6%) and with knowledge of DWI (62.5%) was lower than on DWI (97.1%). The sensitivity of FLAIR increased with increasing time from symptom onset from 27.0/50.0%

AB - OBJECTIVE: o evaluate the use of fluid-attenuated inversion recovery (FLAIR) imaging as surrogate marker of lesion age within the first 6 hours of ischemic stroke. METHODS: e analyzed FLAIR and diffusion-weighted imaging (DWI) sequences performed within 6 hours of symptom onset in 120 consecutive patients with ischemic stroke with known symptom onset. The visibility of acute ischemic lesions on FLAIR images was judged in two steps (on FLAIR alone and with knowledge of DWI) and compared with DWI. RESULTS: egative FLAIR in the case of positive DWI allocated ischemic lesions to a time window 3 hours or less with a high specificity (0.93) and a high positive predictive value (0.94), whereas sensitivity (0.48) and negative predictive value (0.43) were low. Lesion visibility on FLAIR images alone (35.6%) and with knowledge of DWI (62.5%) was lower than on DWI (97.1%). The sensitivity of FLAIR increased with increasing time from symptom onset from 27.0/50.0%

M3 - SCORING: Zeitschriftenaufsatz

VL - 65

SP - 724

EP - 732

JO - ANN NEUROL

JF - ANN NEUROL

SN - 0364-5134

IS - 6

M1 - 6

ER -