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NAADP Signaling: New Kids on the Block

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NAADP Signaling: New Kids on the Block. / Guse, Andreas H.

in: CELLS-BASEL, Jahrgang 11, Nr. 6, 1054, 21.03.2022.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › Andere (Vorworte u.ä.) › Forschung

Harvard

Guse, AH 2022, 'NAADP Signaling: New Kids on the Block', CELLS-BASEL, Jg. 11, Nr. 6, 1054. https://doi.org/10.3390/cells11061054

APA

Guse, A. H. (2022). NAADP Signaling: New Kids on the Block. CELLS-BASEL, 11(6), [1054]. https://doi.org/10.3390/cells11061054

Vancouver

Guse AH. NAADP Signaling: New Kids on the Block. CELLS-BASEL. 2022 Mär 21;11(6). 1054. https://doi.org/10.3390/cells11061054

Bibtex

@article{64e7afcd296642b89d21edcfb412b0f8,
title = "NAADP Signaling: New Kids on the Block",
abstract = "Nicotinic acid adenine dinucleotide phosphate (NAADP) is a universal Ca2+ mobilizing second messenger essential for initiation of Ca2+ signaling. Recently, novel molecular mechanisms of both its rapid formation upon receptor stimulation and its mode of action were discovered. Dual NADPH oxidase 2 (DUOX2) and hematological and neurological expressed 1-like protein (HN1L)/Jupiter microtubule-associated homolog 2 (JPT2) were discovered as NAADP-forming enzyme and NAADP receptor/binding protein-the new kids on the block. These novel aspects are reviewed and integrated into the previous view of NAADP signaling.",
keywords = "Calcium/metabolism, Calcium Signaling, Carrier Proteins/metabolism, NADP/analogs & derivatives, Second Messenger Systems",
author = "Guse, {Andreas H}",
year = "2022",
month = mar,
day = "21",
doi = "10.3390/cells11061054",
language = "English",
volume = "11",
journal = "CELLS-BASEL",
issn = "2073-4409",
publisher = "MDPI Multidisciplinary Digital Publishing Institute",
number = "6",

}

RIS

TY - JOUR

T1 - NAADP Signaling: New Kids on the Block

AU - Guse, Andreas H

PY - 2022/3/21

Y1 - 2022/3/21

N2 - Nicotinic acid adenine dinucleotide phosphate (NAADP) is a universal Ca2+ mobilizing second messenger essential for initiation of Ca2+ signaling. Recently, novel molecular mechanisms of both its rapid formation upon receptor stimulation and its mode of action were discovered. Dual NADPH oxidase 2 (DUOX2) and hematological and neurological expressed 1-like protein (HN1L)/Jupiter microtubule-associated homolog 2 (JPT2) were discovered as NAADP-forming enzyme and NAADP receptor/binding protein-the new kids on the block. These novel aspects are reviewed and integrated into the previous view of NAADP signaling.

AB - Nicotinic acid adenine dinucleotide phosphate (NAADP) is a universal Ca2+ mobilizing second messenger essential for initiation of Ca2+ signaling. Recently, novel molecular mechanisms of both its rapid formation upon receptor stimulation and its mode of action were discovered. Dual NADPH oxidase 2 (DUOX2) and hematological and neurological expressed 1-like protein (HN1L)/Jupiter microtubule-associated homolog 2 (JPT2) were discovered as NAADP-forming enzyme and NAADP receptor/binding protein-the new kids on the block. These novel aspects are reviewed and integrated into the previous view of NAADP signaling.

KW - Calcium/metabolism

KW - Calcium Signaling

KW - Carrier Proteins/metabolism

KW - NADP/analogs & derivatives

KW - Second Messenger Systems

U2 - 10.3390/cells11061054

DO - 10.3390/cells11061054

M3 - Other (editorial matter etc.)

C2 - 35326505

VL - 11

JO - CELLS-BASEL

JF - CELLS-BASEL

SN - 2073-4409

IS - 6

M1 - 1054

ER -