Modelling epidermal homeostasis as an approach for clinical bioinformatics.

Standard

Modelling epidermal homeostasis as an approach for clinical bioinformatics. / Grabe, Niels; Pommerencke, Thora; Müller, Dennis; Huber, Simone; Neuber, Karsten; Dickhaus, Hartmut.

in: Stud Health Technol Inform, Jahrgang 124, 2006, S. 105-110.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Grabe, N, Pommerencke, T, Müller, D, Huber, S, Neuber, K & Dickhaus, H 2006, 'Modelling epidermal homeostasis as an approach for clinical bioinformatics.', Stud Health Technol Inform, Jg. 124, S. 105-110. <http://www.ncbi.nlm.nih.gov/pubmed/17108511?dopt=Citation>

APA

Grabe, N., Pommerencke, T., Müller, D., Huber, S., Neuber, K., & Dickhaus, H. (2006). Modelling epidermal homeostasis as an approach for clinical bioinformatics. Stud Health Technol Inform, 124, 105-110. http://www.ncbi.nlm.nih.gov/pubmed/17108511?dopt=Citation

Vancouver

Grabe N, Pommerencke T, Müller D, Huber S, Neuber K, Dickhaus H. Modelling epidermal homeostasis as an approach for clinical bioinformatics. Stud Health Technol Inform. 2006;124:105-110.

Bibtex

@article{a0a670301c01448b9475e2f8dee51167,
title = "Modelling epidermal homeostasis as an approach for clinical bioinformatics.",
abstract = "Modelling in systems biology currently lacks clinical applications. As a possible approach leading to clinical relevance the modelling of tissue homeostasis is proposed. As an example a model of epidermal homeostasis is presented which reproduces central morphological and kinetic characteristics of epidermal tissue. Each individual cell is modelled as an agent. The tissue arises as an emergent phenomenon from the interactions of agents. Each agent's behaviour is qualitatively modelled by a simple differentiation state-flow program. Epithelialisation under the influence of parameters concerning stem-cell location is briefly demonstrated.",
author = "Niels Grabe and Thora Pommerencke and Dennis M{\"u}ller and Simone Huber and Karsten Neuber and Hartmut Dickhaus",
year = "2006",
language = "Deutsch",
volume = "124",
pages = "105--110",

}

RIS

TY - JOUR

T1 - Modelling epidermal homeostasis as an approach for clinical bioinformatics.

AU - Grabe, Niels

AU - Pommerencke, Thora

AU - Müller, Dennis

AU - Huber, Simone

AU - Neuber, Karsten

AU - Dickhaus, Hartmut

PY - 2006

Y1 - 2006

N2 - Modelling in systems biology currently lacks clinical applications. As a possible approach leading to clinical relevance the modelling of tissue homeostasis is proposed. As an example a model of epidermal homeostasis is presented which reproduces central morphological and kinetic characteristics of epidermal tissue. Each individual cell is modelled as an agent. The tissue arises as an emergent phenomenon from the interactions of agents. Each agent's behaviour is qualitatively modelled by a simple differentiation state-flow program. Epithelialisation under the influence of parameters concerning stem-cell location is briefly demonstrated.

AB - Modelling in systems biology currently lacks clinical applications. As a possible approach leading to clinical relevance the modelling of tissue homeostasis is proposed. As an example a model of epidermal homeostasis is presented which reproduces central morphological and kinetic characteristics of epidermal tissue. Each individual cell is modelled as an agent. The tissue arises as an emergent phenomenon from the interactions of agents. Each agent's behaviour is qualitatively modelled by a simple differentiation state-flow program. Epithelialisation under the influence of parameters concerning stem-cell location is briefly demonstrated.

M3 - SCORING: Zeitschriftenaufsatz

VL - 124

SP - 105

EP - 110

ER -