Microbial interactions in Staphylococcus epidermidis biofilms

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Microbial interactions in Staphylococcus epidermidis biofilms. / Mack, Dietrich; Davies, Angharad P; Harris, Llinos G; Rohde, Holger; Horstkotte, Matthias A; Knobloch, Johannes K-M.

in: ANAL BIOANAL CHEM, Jahrgang 387, Nr. 2, 2, 2007, S. 399-408.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{fe356d75bcac4c1ca18534736ee8f990,
title = "Microbial interactions in Staphylococcus epidermidis biofilms",
abstract = "Medical device-associated infections, most frequently caused by coagulase-negative staphylococci, especially Staphylococcus epidermidis, are of increasing importance in modern medicine. The formation of adherent, multilayered bacterial biofilms is the most important factor in the pathogenesis of these infections, which regularly fail to respond to appropriate antimicrobial therapy. Progress in elucidating the factors functional in elaboration of S. epidermidis biofilms and the regulation of their expression with a special emphasis on the role of quorum sensing are reviewed. Significant progress has been made in recent years, which provides the rationale for developing better preventive, therapeutic and diagnostic measures.",
author = "Dietrich Mack and Davies, {Angharad P} and Harris, {Llinos G} and Holger Rohde and Horstkotte, {Matthias A} and Knobloch, {Johannes K-M}",
year = "2007",
doi = "10.1007/s00216-006-0745-2",
language = "English",
volume = "387",
pages = "399--408",
journal = "ANAL BIOANAL CHEM",
issn = "1618-2642",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Microbial interactions in Staphylococcus epidermidis biofilms

AU - Mack, Dietrich

AU - Davies, Angharad P

AU - Harris, Llinos G

AU - Rohde, Holger

AU - Horstkotte, Matthias A

AU - Knobloch, Johannes K-M

PY - 2007

Y1 - 2007

N2 - Medical device-associated infections, most frequently caused by coagulase-negative staphylococci, especially Staphylococcus epidermidis, are of increasing importance in modern medicine. The formation of adherent, multilayered bacterial biofilms is the most important factor in the pathogenesis of these infections, which regularly fail to respond to appropriate antimicrobial therapy. Progress in elucidating the factors functional in elaboration of S. epidermidis biofilms and the regulation of their expression with a special emphasis on the role of quorum sensing are reviewed. Significant progress has been made in recent years, which provides the rationale for developing better preventive, therapeutic and diagnostic measures.

AB - Medical device-associated infections, most frequently caused by coagulase-negative staphylococci, especially Staphylococcus epidermidis, are of increasing importance in modern medicine. The formation of adherent, multilayered bacterial biofilms is the most important factor in the pathogenesis of these infections, which regularly fail to respond to appropriate antimicrobial therapy. Progress in elucidating the factors functional in elaboration of S. epidermidis biofilms and the regulation of their expression with a special emphasis on the role of quorum sensing are reviewed. Significant progress has been made in recent years, which provides the rationale for developing better preventive, therapeutic and diagnostic measures.

U2 - 10.1007/s00216-006-0745-2

DO - 10.1007/s00216-006-0745-2

M3 - SCORING: Journal article

VL - 387

SP - 399

EP - 408

JO - ANAL BIOANAL CHEM

JF - ANAL BIOANAL CHEM

SN - 1618-2642

IS - 2

M1 - 2

ER -