Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study.

Jan P Bremer; Sebastian Ullrich; Martin Laudien; Wolfgang L Gross; Peter Lamprecht

Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study.

Standard

Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study. / Bremer, Jan P; Ullrich, Sebastian; Laudien, Martin; Gross, Wolfgang L; Lamprecht, Peter.

in: CLIN EXP RHEUMATOL, Jahrgang 28(1 Suppl 57), 2010, S. 67-71.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Bremer, JP, Ullrich, S, Laudien, M, Gross, WL & Lamprecht, P 2010, 'Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study.', CLIN EXP RHEUMATOL, Jg. 28(1 Suppl 57), S. 67-71. <http://www.ncbi.nlm.nih.gov/pubmed/20412706?dopt=Citation>

APA

Bremer, J. P., Ullrich, S., Laudien, M., Gross, W. L., & Lamprecht, P. (2010). Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study. CLIN EXP RHEUMATOL, 28(1 Suppl 57), 67-71. http://www.ncbi.nlm.nih.gov/pubmed/20412706?dopt=Citation

Vancouver

Bremer JP, Ullrich S, Laudien M, Gross WL, Lamprecht P. Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study. CLIN EXP RHEUMATOL. 2010;28(1 Suppl 57):67-71.

Bibtex

@article{9790a6116aa744929f4ace4c3ee4ebf1,

title = "Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study.",

abstract = "While remission is achieved in the majority of Wegener's granulomatosis (WG)-patients with cyclophosphamide, maintenance of remission remains a challenge due to the high rate of relapses. The purpose of this study was to evaluate the safety and efficacy of the combination of methotrexate (MTX) plus leflunomide (LEF) for the treatment of minor relapsing WG not warranting cyclophosphamide.",

keywords = "Adult, Humans, Male, Aged, Female, Middle Aged, Adolescent, Young Adult, dosage, control, Retrospective Studies, Remission Induction, Drug Therapy, Combination, Recurrence prevention, Immunosuppressive Agents administration, Anti-Inflammatory Agents, Non-Steroidal administration, Isoxazoles administration, Methotrexate administration, Wegener Granulomatosis drug therapy, Adult, Humans, Male, Aged, Female, Middle Aged, Adolescent, Young Adult, dosage, control, Retrospective Studies, Remission Induction, Drug Therapy, Combination, Recurrence prevention, Immunosuppressive Agents administration, Anti-Inflammatory Agents, Non-Steroidal administration, Isoxazoles administration, Methotrexate administration, Wegener Granulomatosis drug therapy",

author = "Bremer, {Jan P} and Sebastian Ullrich and Martin Laudien and Gross, {Wolfgang L} and Peter Lamprecht",

year = "2010",

language = "Deutsch",

volume = "28(1 Suppl 57)",

pages = "67--71",

journal = "CLIN EXP RHEUMATOL",

issn = "0392-856X",

publisher = "Clinical and Experimental Rheumatology S.A.S.",

}

RIS

TY - JOUR

T1 - Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study.

AU - Bremer, Jan P

AU - Ullrich, Sebastian

AU - Laudien, Martin

AU - Gross, Wolfgang L

AU - Lamprecht, Peter

PY - 2010

Y1 - 2010

N2 - While remission is achieved in the majority of Wegener's granulomatosis (WG)-patients with cyclophosphamide, maintenance of remission remains a challenge due to the high rate of relapses. The purpose of this study was to evaluate the safety and efficacy of the combination of methotrexate (MTX) plus leflunomide (LEF) for the treatment of minor relapsing WG not warranting cyclophosphamide.

AB - While remission is achieved in the majority of Wegener's granulomatosis (WG)-patients with cyclophosphamide, maintenance of remission remains a challenge due to the high rate of relapses. The purpose of this study was to evaluate the safety and efficacy of the combination of methotrexate (MTX) plus leflunomide (LEF) for the treatment of minor relapsing WG not warranting cyclophosphamide.

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Adolescent

KW - Young Adult

KW - dosage

KW - control

KW - Retrospective Studies

KW - Remission Induction

KW - Drug Therapy, Combination

KW - Recurrence prevention

KW - Immunosuppressive Agents administration

KW - Anti-Inflammatory Agents, Non-Steroidal administration

KW - Isoxazoles administration

KW - Methotrexate administration

KW - Wegener Granulomatosis drug therapy