Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity

Standard

Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity. / Leshchenko, Elena V; Antonov, Alexandr S; Dyshlovoy, Sergey A; Berdyshev, Dmitrii V; Hauschild, Jessica; Zhuravleva, Olesya I; Menshov, Alexander S; Kirichuk, Natalya N; Popov, Roman S; Gerasimenko, Andrey V; Udovenko, Anatoly A; Graefen, Markus; Bokemeyer, Carsten; von Amsberg, Gunhild; Yurchenko, Anton N.

in: J NAT PROD, Jahrgang 85, Nr. 12, 23.12.2022, S. 2746-2752.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Leshchenko, EV, Antonov, AS, Dyshlovoy, SA, Berdyshev, DV, Hauschild, J, Zhuravleva, OI, Menshov, AS, Kirichuk, NN, Popov, RS, Gerasimenko, AV, Udovenko, AA, Graefen, M, Bokemeyer, C, von Amsberg, G & Yurchenko, AN 2022, 'Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity', J NAT PROD, Jg. 85, Nr. 12, S. 2746-2752. https://doi.org/10.1021/acs.jnatprod.2c00677

APA

Leshchenko, E. V., Antonov, A. S., Dyshlovoy, S. A., Berdyshev, D. V., Hauschild, J., Zhuravleva, O. I., Menshov, A. S., Kirichuk, N. N., Popov, R. S., Gerasimenko, A. V., Udovenko, A. A., Graefen, M., Bokemeyer, C., von Amsberg, G., & Yurchenko, A. N. (2022). Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity. J NAT PROD, 85(12), 2746-2752. https://doi.org/10.1021/acs.jnatprod.2c00677

Vancouver

Bibtex

@article{0182e3fb08484eb79f7354e7ddcaa947,
title = "Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity",
abstract = "New meroterpenoids, meroantarctines A-C (1-3), with unique 6/5/6/6, 6/5/6/5/6, and 6/5/6/5 polycyclic systems were isolated from the alga-derived fungus Penicillium antarcticum KMM 4685. Their structures were elucidated by spectroscopic methods, X-ray diffraction, and quantum chemical calculations. A biogenetic pathway for 1-3 was proposed. Meroantarctines A-C (1-3) inhibited p-glycoprotein activity and could resensitize drug-resistant cancer cells to docetaxel.",
author = "Leshchenko, {Elena V} and Antonov, {Alexandr S} and Dyshlovoy, {Sergey A} and Berdyshev, {Dmitrii V} and Jessica Hauschild and Zhuravleva, {Olesya I} and Menshov, {Alexander S} and Kirichuk, {Natalya N} and Popov, {Roman S} and Gerasimenko, {Andrey V} and Udovenko, {Anatoly A} and Markus Graefen and Carsten Bokemeyer and {von Amsberg}, Gunhild and Yurchenko, {Anton N}",
year = "2022",
month = dec,
day = "23",
doi = "10.1021/acs.jnatprod.2c00677",
language = "English",
volume = "85",
pages = "2746--2752",
journal = "J NAT PROD",
issn = "0163-3864",
publisher = "American Chemical Society",
number = "12",

}

RIS

TY - JOUR

T1 - Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity

AU - Leshchenko, Elena V

AU - Antonov, Alexandr S

AU - Dyshlovoy, Sergey A

AU - Berdyshev, Dmitrii V

AU - Hauschild, Jessica

AU - Zhuravleva, Olesya I

AU - Menshov, Alexander S

AU - Kirichuk, Natalya N

AU - Popov, Roman S

AU - Gerasimenko, Andrey V

AU - Udovenko, Anatoly A

AU - Graefen, Markus

AU - Bokemeyer, Carsten

AU - von Amsberg, Gunhild

AU - Yurchenko, Anton N

PY - 2022/12/23

Y1 - 2022/12/23

N2 - New meroterpenoids, meroantarctines A-C (1-3), with unique 6/5/6/6, 6/5/6/5/6, and 6/5/6/5 polycyclic systems were isolated from the alga-derived fungus Penicillium antarcticum KMM 4685. Their structures were elucidated by spectroscopic methods, X-ray diffraction, and quantum chemical calculations. A biogenetic pathway for 1-3 was proposed. Meroantarctines A-C (1-3) inhibited p-glycoprotein activity and could resensitize drug-resistant cancer cells to docetaxel.

AB - New meroterpenoids, meroantarctines A-C (1-3), with unique 6/5/6/6, 6/5/6/5/6, and 6/5/6/5 polycyclic systems were isolated from the alga-derived fungus Penicillium antarcticum KMM 4685. Their structures were elucidated by spectroscopic methods, X-ray diffraction, and quantum chemical calculations. A biogenetic pathway for 1-3 was proposed. Meroantarctines A-C (1-3) inhibited p-glycoprotein activity and could resensitize drug-resistant cancer cells to docetaxel.

U2 - 10.1021/acs.jnatprod.2c00677

DO - 10.1021/acs.jnatprod.2c00677

M3 - SCORING: Journal article

C2 - 36413729

VL - 85

SP - 2746

EP - 2752

JO - J NAT PROD

JF - J NAT PROD

SN - 0163-3864

IS - 12

ER -