PortalPublikationenMaternal microchimerism: lessons learned from murine models.

Maternal microchimerism: lessons learned from murine models.

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Maternal microchimerism: lessons learned from murine models. / Stelzer, Ina; Thiele, Kristin; Solano, Maria Emilia.

in: J REPROD IMMUNOL, Jahrgang 108, Nr. SI, 04.2015, S. 12-25.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Stelzer, I, Thiele, K & Solano, ME 2015, 'Maternal microchimerism: lessons learned from murine models.', J REPROD IMMUNOL, Jg. 108, Nr. SI, S. 12-25. https://doi.org/10.1016/j.jri.2014.12.007.

APA

Stelzer, I., Thiele, K., & Solano, M. E. (2015). Maternal microchimerism: lessons learned from murine models. J REPROD IMMUNOL, 108(SI), 12-25. https://doi.org/10.1016/j.jri.2014.12.007.

Vancouver

Stelzer I, Thiele K, Solano ME. Maternal microchimerism: lessons learned from murine models. J REPROD IMMUNOL. 2015 Apr;108(SI):12-25. https://doi.org/10.1016/j.jri.2014.12.007.

Bibtex

@article{563153dc27e7444a93e5dc41a9a7ce15,
title = "Maternal microchimerism: lessons learned from murine models.",
abstract = "The presence of maternal cells in the organs of the offspring is referred to as maternal microchimerism (MMc). MMc is physiologically acquired during pregnancy and lactation and can persist until adulthood. The detection of MMc in a variety of human diseases has raised interest in the short- and long-term functional consequences for the offspring. Owing to limited availability and access to human tissue, mouse models have become an essential tool in elucidating the functional role of MMc. This review compiles the detection techniques and experimental settings used in murine MMc research. It aims to summarize the potential mechanisms of migration of MMc, pre- and postnatal tissue distribution, phenotype and concatenated function, as well as factors modulating its occurrence. In this context, we propose MMc to be a materno-fetal messenger with the capacity to critically shape the development of the offspring's immunity.",
author = "Ina Stelzer and Kristin Thiele and Solano, {Maria Emilia}",
year = "2015",
month = apr,
doi = "10.1016/j.jri.2014.12.007.",
language = "English",
volume = "108",
pages = "12--25",
journal = "J REPROD IMMUNOL",
issn = "0165-0378",
publisher = "Elsevier Ireland Ltd",
number = "SI",

}

RIS

TY - JOUR

T1 - Maternal microchimerism: lessons learned from murine models.

AU - Stelzer, Ina

AU - Thiele, Kristin

AU - Solano, Maria Emilia

PY - 2015/4

Y1 - 2015/4

N2 - The presence of maternal cells in the organs of the offspring is referred to as maternal microchimerism (MMc). MMc is physiologically acquired during pregnancy and lactation and can persist until adulthood. The detection of MMc in a variety of human diseases has raised interest in the short- and long-term functional consequences for the offspring. Owing to limited availability and access to human tissue, mouse models have become an essential tool in elucidating the functional role of MMc. This review compiles the detection techniques and experimental settings used in murine MMc research. It aims to summarize the potential mechanisms of migration of MMc, pre- and postnatal tissue distribution, phenotype and concatenated function, as well as factors modulating its occurrence. In this context, we propose MMc to be a materno-fetal messenger with the capacity to critically shape the development of the offspring's immunity.

AB - The presence of maternal cells in the organs of the offspring is referred to as maternal microchimerism (MMc). MMc is physiologically acquired during pregnancy and lactation and can persist until adulthood. The detection of MMc in a variety of human diseases has raised interest in the short- and long-term functional consequences for the offspring. Owing to limited availability and access to human tissue, mouse models have become an essential tool in elucidating the functional role of MMc. This review compiles the detection techniques and experimental settings used in murine MMc research. It aims to summarize the potential mechanisms of migration of MMc, pre- and postnatal tissue distribution, phenotype and concatenated function, as well as factors modulating its occurrence. In this context, we propose MMc to be a materno-fetal messenger with the capacity to critically shape the development of the offspring's immunity.

U2 - 10.1016/j.jri.2014.12.007.

DO - 10.1016/j.jri.2014.12.007.

M3 - SCORING: Journal article

VL - 108

SP - 12

EP - 25

JO - J REPROD IMMUNOL

JF - J REPROD IMMUNOL

SN - 0165-0378

IS - SI

ER -