Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression.
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Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression. / Anders, Mario; Vieth, M; Röcken, C; Ebert, M; Pross, M; Gretschel, S; Schlag, P M; Wiedenmann, B; Kemmner, W; Höcker, M.
in: BRIT J CANCER, Jahrgang 100, Nr. 2, 2, 2009, S. 352-359.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression.
AU - Anders, Mario
AU - Vieth, M
AU - Röcken, C
AU - Ebert, M
AU - Pross, M
AU - Gretschel, S
AU - Schlag, P M
AU - Wiedenmann, B
AU - Kemmner, W
AU - Höcker, M
PY - 2009
Y1 - 2009
N2 - Loss of the coxsackie and adenovirus receptor (CAR) has previously been observed in gastric cancer. The role of CAR in gastric cancer pathobiology, however, is unclear. We therefore analysed CAR in 196 R(0)-resected gastric adenocarcinomas and non-cancerous gastric mucosa samples using immunohistochemistry and immunofluorescence. Coxsackie and adenovirus receptor was found at the surface and foveolar epithelium of all non-neoplastic gastric mucosa samples (n=175), whereas only 56% of gastric cancer specimens showed CAR positivity (P
AB - Loss of the coxsackie and adenovirus receptor (CAR) has previously been observed in gastric cancer. The role of CAR in gastric cancer pathobiology, however, is unclear. We therefore analysed CAR in 196 R(0)-resected gastric adenocarcinomas and non-cancerous gastric mucosa samples using immunohistochemistry and immunofluorescence. Coxsackie and adenovirus receptor was found at the surface and foveolar epithelium of all non-neoplastic gastric mucosa samples (n=175), whereas only 56% of gastric cancer specimens showed CAR positivity (P
M3 - SCORING: Zeitschriftenaufsatz
VL - 100
SP - 352
EP - 359
JO - BRIT J CANCER
JF - BRIT J CANCER
SN - 0007-0920
IS - 2
M1 - 2
ER -