Lectin histochemistry of metastatic adenocarcinomas of the lung.

Ina Thoem; Olaf Schult-Kronefeld; Iris Burkholder; Michael Goern; Birte Andritzky; Katharina Blonski; Christian Kugler; Lutz Edler; Carsten Bokemeyer; Udo Schumacher; Eckart Laack

Lectin histochemistry of metastatic adenocarcinomas of the lung.

Standard

Lectin histochemistry of metastatic adenocarcinomas of the lung. / Thoem, Ina; Schult-Kronefeld, Olaf; Burkholder, Iris; Goern, Michael; Andritzky, Birte; Blonski, Katharina; Kugler, Christian; Edler, Lutz; Bokemeyer, Carsten ; Schumacher, Udo; Laack, Eckart.

in: LUNG CANCER, Jahrgang 56, Nr. 3, 3, 2007, S. 391-397.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Thoem, I, Schult-Kronefeld, O, Burkholder, I, Goern, M, Andritzky, B, Blonski, K, Kugler, C, Edler, L, Bokemeyer, C , Schumacher, U & Laack, E 2007, 'Lectin histochemistry of metastatic adenocarcinomas of the lung.', LUNG CANCER, Jg. 56, Nr. 3, 3, S. 391-397. <http://www.ncbi.nlm.nih.gov/pubmed/17306412?dopt=Citation>

APA

Thoem, I., Schult-Kronefeld, O., Burkholder, I., Goern, M., Andritzky, B., Blonski, K., Kugler, C., Edler, L., Bokemeyer, C., Schumacher, U., & Laack, E. (2007). Lectin histochemistry of metastatic adenocarcinomas of the lung. LUNG CANCER, 56(3), 391-397. [3]. http://www.ncbi.nlm.nih.gov/pubmed/17306412?dopt=Citation

Vancouver

Thoem I, Schult-Kronefeld O, Burkholder I, Goern M, Andritzky B, Blonski K et al. Lectin histochemistry of metastatic adenocarcinomas of the lung. LUNG CANCER. 2007;56(3):391-397. 3.

Bibtex

@article{0637c082b72b4ed5b8b34dbd537df745,

title = "Lectin histochemistry of metastatic adenocarcinomas of the lung.",

abstract = "BACKGROUND: Several clinical studies indicate that primary tumour cells with high metastatic potential often show aberrant glycosylation as detected by lectin histochemistry. However, it is unclear whether aberrant glycosylation is still present in metastatic deposits. The aim of the present investigation was thus to analyse a possible association between the presence of lectin binding sites of pulmonary adenocarcinoma cells and their lymph node and haematogenous metastatic cells. METHODS: For this purpose, the expression of HPA, PHA-L and UEA-I was assessed in primary tumours, lymph node metastases and haematogenous metastases of 96 patients with metastatic adenocarcinomas of the lung that underwent surgery between 1999 and 2002. Besides, lectin-binding data and other known prognostic factors were correlated with survival. RESULTS: We found a significant positive correlation between the binding of the lectins HPA (p=0.002), PHA-L (p",

author = "Ina Thoem and Olaf Schult-Kronefeld and Iris Burkholder and Michael Goern and Birte Andritzky and Katharina Blonski and Christian Kugler and Lutz Edler and Carsten Bokemeyer and Udo Schumacher and Eckart Laack",

year = "2007",

language = "Deutsch",

volume = "56",

pages = "391--397",

journal = "LUNG CANCER",

issn = "0169-5002",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

RIS

TY - JOUR

T1 - Lectin histochemistry of metastatic adenocarcinomas of the lung.

AU - Thoem, Ina

AU - Schult-Kronefeld, Olaf

AU - Burkholder, Iris

AU - Goern, Michael

AU - Andritzky, Birte

AU - Blonski, Katharina

AU - Kugler, Christian

AU - Edler, Lutz

AU - Bokemeyer, Carsten

AU - Schumacher, Udo

AU - Laack, Eckart

PY - 2007

Y1 - 2007

N2 - BACKGROUND: Several clinical studies indicate that primary tumour cells with high metastatic potential often show aberrant glycosylation as detected by lectin histochemistry. However, it is unclear whether aberrant glycosylation is still present in metastatic deposits. The aim of the present investigation was thus to analyse a possible association between the presence of lectin binding sites of pulmonary adenocarcinoma cells and their lymph node and haematogenous metastatic cells. METHODS: For this purpose, the expression of HPA, PHA-L and UEA-I was assessed in primary tumours, lymph node metastases and haematogenous metastases of 96 patients with metastatic adenocarcinomas of the lung that underwent surgery between 1999 and 2002. Besides, lectin-binding data and other known prognostic factors were correlated with survival. RESULTS: We found a significant positive correlation between the binding of the lectins HPA (p=0.002), PHA-L (p

AB - BACKGROUND: Several clinical studies indicate that primary tumour cells with high metastatic potential often show aberrant glycosylation as detected by lectin histochemistry. However, it is unclear whether aberrant glycosylation is still present in metastatic deposits. The aim of the present investigation was thus to analyse a possible association between the presence of lectin binding sites of pulmonary adenocarcinoma cells and their lymph node and haematogenous metastatic cells. METHODS: For this purpose, the expression of HPA, PHA-L and UEA-I was assessed in primary tumours, lymph node metastases and haematogenous metastases of 96 patients with metastatic adenocarcinomas of the lung that underwent surgery between 1999 and 2002. Besides, lectin-binding data and other known prognostic factors were correlated with survival. RESULTS: We found a significant positive correlation between the binding of the lectins HPA (p=0.002), PHA-L (p

M3 - SCORING: Zeitschriftenaufsatz

VL - 56

SP - 391

EP - 397

JO - LUNG CANCER

JF - LUNG CANCER

SN - 0169-5002

IS - 3

M1 - 3

ER -