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L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.

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L1 is associated with micrometastatic spread and poor outcome in colorectal cancer. / Kaifi, Jussuf; Reichelt, Uta; Quaas, Alexander; Schurr, Paulus; Wachowiak, Robin; Yekebas, Emre F.; Strate, Tim; Schneider, Claus G.; Pantel, Klaus; Schachner, Melitta; Sauter, Guido; Izbicki, Jakob R.

in: MODERN PATHOL, Jahrgang 20, Nr. 11, 11, 2007, S. 1183-1190.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kaifi, J, Reichelt, U, Quaas, A, Schurr, P, Wachowiak, R, Yekebas, EF, Strate, T, Schneider, CG, Pantel, K, Schachner, M, Sauter, G & Izbicki, JR 2007, 'L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.', MODERN PATHOL, Jg. 20, Nr. 11, 11, S. 1183-1190. <http://www.ncbi.nlm.nih.gov/pubmed/17873897?dopt=Citation>

APA

Kaifi, J., Reichelt, U., Quaas, A., Schurr, P., Wachowiak, R., Yekebas, E. F., Strate, T., Schneider, C. G., Pantel, K., Schachner, M., Sauter, G., & Izbicki, J. R. (2007). L1 is associated with micrometastatic spread and poor outcome in colorectal cancer. MODERN PATHOL, 20(11), 1183-1190. [11]. http://www.ncbi.nlm.nih.gov/pubmed/17873897?dopt=Citation

Vancouver

Kaifi J, Reichelt U, Quaas A, Schurr P, Wachowiak R, Yekebas EF et al. L1 is associated with micrometastatic spread and poor outcome in colorectal cancer. MODERN PATHOL. 2007;20(11):1183-1190. 11.

Bibtex

@article{f1fd78aab942455e9c4692a835465d58,
title = "L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.",
abstract = "L1 is a cell adhesion molecule expressed at the invasive front of colorectal tumors with an important role in metastasis. The aim of the present study was to determine L1 protein expression in a large cohort of colorectal cancer patients and its impact on early metastatic spread and survival. A total of 375 patients that underwent surgical treatment for colorectal cancer were chosen retrospectively. A tissue microarray was constructed of 576 tissue samples from these patients and analyzed by immunohistochemistry with a monoclonal antibody against human L1 (UJ127). Lymph node and bone marrow micrometastasis were assessed with monoclonal antibodies Ber-EP4 and pancytokeratin A45-B/B3, respectively. Associations between L1 expression and lymph node, bone marrow micrometastasis and survival were investigated with Fisher's, log-rank test and Cox multivariate analysis. All statistical tests were two-sided. L1 was detected in a subset of 48 (13%) of 375 patients examined. Analysis of L1 expression and survival revealed a significantly worse outcome for L1-positive patients by log-rank test (P",
author = "Jussuf Kaifi and Uta Reichelt and Alexander Quaas and Paulus Schurr and Robin Wachowiak and Yekebas, {Emre F.} and Tim Strate and Schneider, {Claus G.} and Klaus Pantel and Melitta Schachner and Guido Sauter and Izbicki, {Jakob R.}",
year = "2007",
language = "Deutsch",
volume = "20",
pages = "1183--1190",
journal = "MODERN PATHOL",
issn = "0893-3952",
publisher = "NATURE PUBLISHING GROUP",
number = "11",

}

RIS

TY - JOUR

T1 - L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.

AU - Kaifi, Jussuf

AU - Reichelt, Uta

AU - Quaas, Alexander

AU - Schurr, Paulus

AU - Wachowiak, Robin

AU - Yekebas, Emre F.

AU - Strate, Tim

AU - Schneider, Claus G.

AU - Pantel, Klaus

AU - Schachner, Melitta

AU - Sauter, Guido

AU - Izbicki, Jakob R.

PY - 2007

Y1 - 2007

N2 - L1 is a cell adhesion molecule expressed at the invasive front of colorectal tumors with an important role in metastasis. The aim of the present study was to determine L1 protein expression in a large cohort of colorectal cancer patients and its impact on early metastatic spread and survival. A total of 375 patients that underwent surgical treatment for colorectal cancer were chosen retrospectively. A tissue microarray was constructed of 576 tissue samples from these patients and analyzed by immunohistochemistry with a monoclonal antibody against human L1 (UJ127). Lymph node and bone marrow micrometastasis were assessed with monoclonal antibodies Ber-EP4 and pancytokeratin A45-B/B3, respectively. Associations between L1 expression and lymph node, bone marrow micrometastasis and survival were investigated with Fisher's, log-rank test and Cox multivariate analysis. All statistical tests were two-sided. L1 was detected in a subset of 48 (13%) of 375 patients examined. Analysis of L1 expression and survival revealed a significantly worse outcome for L1-positive patients by log-rank test (P

AB - L1 is a cell adhesion molecule expressed at the invasive front of colorectal tumors with an important role in metastasis. The aim of the present study was to determine L1 protein expression in a large cohort of colorectal cancer patients and its impact on early metastatic spread and survival. A total of 375 patients that underwent surgical treatment for colorectal cancer were chosen retrospectively. A tissue microarray was constructed of 576 tissue samples from these patients and analyzed by immunohistochemistry with a monoclonal antibody against human L1 (UJ127). Lymph node and bone marrow micrometastasis were assessed with monoclonal antibodies Ber-EP4 and pancytokeratin A45-B/B3, respectively. Associations between L1 expression and lymph node, bone marrow micrometastasis and survival were investigated with Fisher's, log-rank test and Cox multivariate analysis. All statistical tests were two-sided. L1 was detected in a subset of 48 (13%) of 375 patients examined. Analysis of L1 expression and survival revealed a significantly worse outcome for L1-positive patients by log-rank test (P

M3 - SCORING: Zeitschriftenaufsatz

VL - 20

SP - 1183

EP - 1190

JO - MODERN PATHOL

JF - MODERN PATHOL

SN - 0893-3952

IS - 11

M1 - 11

ER -