Isoprostanes and neuroprostanes: total synthesis, biological activity and biomarkers of oxidative stress in humans
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Isoprostanes and neuroprostanes: total synthesis, biological activity and biomarkers of oxidative stress in humans. / Galano, Jean-Marie; Mas, Emilie; Barden, Anne; Mori, Trevor A; Signorini, Cinzia; De Felice, Claudio; Barrett, Aaron; Opere, Catherine; Pinot, Edith; Schwedhelm, Edzard; Benndorf, Ralf; Roy, Jérôme; Le Guennec, Jean-Yves; Oger, Camille; Durand, Thierry.
in: PROSTAG OTH LIPID M, Jahrgang 107, 01.12.2013, S. 95-102.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Isoprostanes and neuroprostanes: total synthesis, biological activity and biomarkers of oxidative stress in humans
AU - Galano, Jean-Marie
AU - Mas, Emilie
AU - Barden, Anne
AU - Mori, Trevor A
AU - Signorini, Cinzia
AU - De Felice, Claudio
AU - Barrett, Aaron
AU - Opere, Catherine
AU - Pinot, Edith
AU - Schwedhelm, Edzard
AU - Benndorf, Ralf
AU - Roy, Jérôme
AU - Le Guennec, Jean-Yves
AU - Oger, Camille
AU - Durand, Thierry
N1 - Copyright © 2013 Elsevier Inc. All rights reserved.
PY - 2013/12/1
Y1 - 2013/12/1
N2 - Isoprostanes (IsoPs) and neuroprostanes (NeuroPs) are formed in vivo by a free radical non-enzymatic mechanism involving peroxidation of arachidonic acid (AA, C20:4 n-6) and docosahexaenoic acid (DHA, C22:6 n-3) respectively. This review summarises our research in the total synthesis of these lipid metabolites, as well as their biological activities and their utility as biomarkers of oxidative stress in humans.
AB - Isoprostanes (IsoPs) and neuroprostanes (NeuroPs) are formed in vivo by a free radical non-enzymatic mechanism involving peroxidation of arachidonic acid (AA, C20:4 n-6) and docosahexaenoic acid (DHA, C22:6 n-3) respectively. This review summarises our research in the total synthesis of these lipid metabolites, as well as their biological activities and their utility as biomarkers of oxidative stress in humans.
U2 - 10.1016/j.prostaglandins.2013.04.003
DO - 10.1016/j.prostaglandins.2013.04.003
M3 - SCORING: Journal article
C2 - 23644158
VL - 107
SP - 95
EP - 102
JO - PROSTAG OTH LIPID M
JF - PROSTAG OTH LIPID M
SN - 1098-8823
ER -