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Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A.

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Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. / Küsters, S; Gantner, F; Künstle, G; Tiegs, Gisa.

in: GASTROENTEROLOGY, Jahrgang 111, Nr. 2, 2, 1996, S. 462-471.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Küsters, S, Gantner, F, Künstle, G & Tiegs, G 1996, 'Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A.', GASTROENTEROLOGY, Jg. 111, Nr. 2, 2, S. 462-471. <http://www.ncbi.nlm.nih.gov/pubmed/8690213?dopt=Citation>

APA

Küsters, S., Gantner, F., Künstle, G., & Tiegs, G. (1996). Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. GASTROENTEROLOGY, 111(2), 462-471. [2]. http://www.ncbi.nlm.nih.gov/pubmed/8690213?dopt=Citation

Vancouver

Küsters S, Gantner F, Künstle G, Tiegs G. Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. GASTROENTEROLOGY. 1996;111(2):462-471. 2.

Bibtex

@article{f37a2c46393f466891e57e4beb389141,
title = "Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A.",
abstract = "T cell-dependent liver injury involving endogenous tumor necrosis factor (TNF) alpha can be induced by either concanavalin A in naive mice or by activating anti-CD3 antibody or staphylococcal enterotoxin B in D-galactosamine-sensitized mice. In this study, the role of interferon gamma (IFN-gamma) in these T-cell models was addressed.",
keywords = "Animals, Male, Mice, Mice, Inbred BALB C, Apoptosis, Lymphocyte Activation, Enzyme-Linked Immunosorbent Assay, Mice, Nude, T-Lymphocytes/*physiology, Concanavalin A/*adverse effects, DNA Damage, Drug-Induced Liver Injury/etiology/metabolism/pathology, Enterotoxins/adverse effects, Galactosamine/adverse effects, Immune Sera/pharmacology, Interferon-gamma/blood/immunology/*physiology, Liver/drug effects/metabolism/*pathology, Liver Failure/chemically induced/metabolism/pathology, Recombinant Proteins/pharmacology, Transaminases/blood, Tumor Necrosis Factor-alpha/metabolism/pharmacology/physiology, Animals, Male, Mice, Mice, Inbred BALB C, Apoptosis, Lymphocyte Activation, Enzyme-Linked Immunosorbent Assay, Mice, Nude, T-Lymphocytes/*physiology, Concanavalin A/*adverse effects, DNA Damage, Drug-Induced Liver Injury/etiology/metabolism/pathology, Enterotoxins/adverse effects, Galactosamine/adverse effects, Immune Sera/pharmacology, Interferon-gamma/blood/immunology/*physiology, Liver/drug effects/metabolism/*pathology, Liver Failure/chemically induced/metabolism/pathology, Recombinant Proteins/pharmacology, Transaminases/blood, Tumor Necrosis Factor-alpha/metabolism/pharmacology/physiology",
author = "S K{\"u}sters and F Gantner and G K{\"u}nstle and Gisa Tiegs",
year = "1996",
language = "English",
volume = "111",
pages = "462--471",
journal = "GASTROENTEROLOGY",
issn = "0016-5085",
publisher = "W.B. Saunders Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A.

AU - Küsters, S

AU - Gantner, F

AU - Künstle, G

AU - Tiegs, Gisa

PY - 1996

Y1 - 1996

N2 - T cell-dependent liver injury involving endogenous tumor necrosis factor (TNF) alpha can be induced by either concanavalin A in naive mice or by activating anti-CD3 antibody or staphylococcal enterotoxin B in D-galactosamine-sensitized mice. In this study, the role of interferon gamma (IFN-gamma) in these T-cell models was addressed.

AB - T cell-dependent liver injury involving endogenous tumor necrosis factor (TNF) alpha can be induced by either concanavalin A in naive mice or by activating anti-CD3 antibody or staphylococcal enterotoxin B in D-galactosamine-sensitized mice. In this study, the role of interferon gamma (IFN-gamma) in these T-cell models was addressed.

KW - Animals

KW - Male

KW - Mice

KW - Mice, Inbred BALB C

KW - Apoptosis

KW - Lymphocyte Activation

KW - Enzyme-Linked Immunosorbent Assay

KW - Mice, Nude

KW - T-Lymphocytes/physiology

KW - Concanavalin A/adverse effects

KW - DNA Damage

KW - Drug-Induced Liver Injury/etiology/metabolism/pathology

KW - Enterotoxins/adverse effects

KW - Galactosamine/adverse effects

KW - Immune Sera/pharmacology

KW - Interferon-gamma/blood/immunology/physiology

KW - Liver/drug effects/metabolism/pathology

KW - Liver Failure/chemically induced/metabolism/pathology

KW - Recombinant Proteins/pharmacology

KW - Transaminases/blood

KW - Tumor Necrosis Factor-alpha/metabolism/pharmacology/physiology

KW - Animals

KW - Male

KW - Mice

KW - Mice, Inbred BALB C

KW - Apoptosis

KW - Lymphocyte Activation

KW - Enzyme-Linked Immunosorbent Assay

KW - Mice, Nude

KW - T-Lymphocytes/physiology

KW - Concanavalin A/adverse effects

KW - DNA Damage

KW - Drug-Induced Liver Injury/etiology/metabolism/pathology

KW - Enterotoxins/adverse effects

KW - Galactosamine/adverse effects

KW - Immune Sera/pharmacology

KW - Interferon-gamma/blood/immunology/physiology

KW - Liver/drug effects/metabolism/pathology

KW - Liver Failure/chemically induced/metabolism/pathology

KW - Recombinant Proteins/pharmacology

KW - Transaminases/blood

KW - Tumor Necrosis Factor-alpha/metabolism/pharmacology/physiology

M3 - SCORING: Journal article

VL - 111

SP - 462

EP - 471

JO - GASTROENTEROLOGY

JF - GASTROENTEROLOGY

SN - 0016-5085

IS - 2

M1 - 2

ER -