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Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers.

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Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers. / Julg, B; Pereyra, F; Buzón, M J; Piechocka-Trocha, A; Clark, M J; Baker, B M; Lian, J; Miura, T; Martinez-Picado, J; Addo, Marylyn; Walker, B D.

in: CLIN INFECT DIS, Jahrgang 51, Nr. 2, 2, 2010, S. 233-238.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Julg, B, Pereyra, F, Buzón, MJ, Piechocka-Trocha, A, Clark, MJ, Baker, BM, Lian, J, Miura, T, Martinez-Picado, J, Addo, M & Walker, BD 2010, 'Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers.', CLIN INFECT DIS, Jg. 51, Nr. 2, 2, S. 233-238. <http://www.ncbi.nlm.nih.gov/pubmed/20550452?dopt=Citation>

APA

Julg, B., Pereyra, F., Buzón, M. J., Piechocka-Trocha, A., Clark, M. J., Baker, B. M., Lian, J., Miura, T., Martinez-Picado, J., Addo, M., & Walker, B. D. (2010). Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers. CLIN INFECT DIS, 51(2), 233-238. [2]. http://www.ncbi.nlm.nih.gov/pubmed/20550452?dopt=Citation

Vancouver

Julg B, Pereyra F, Buzón MJ, Piechocka-Trocha A, Clark MJ, Baker BM et al. Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers. CLIN INFECT DIS. 2010;51(2):233-238. 2.

Bibtex

@article{27887ba57b6243fd91dc69afabc3a2e5,
title = "Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers.",
abstract = "BACKGROUND. Human immunodeficiency virus (HIV) elite controllers are able to control infection with HIV-1 spontaneously to undetectable levels in the absence of antiretroviral therapy, but the mechanisms leading to this phenotype are poorly understood. Although low frequencies of HIV-infected peripheral CD4(+) T cells have been reported in this group, it remains unclear to what extent these are due to viral attenuation, active immune containment, or intracellular host factors that restrict virus replication. METHODS. We assessed proviral DNA levels, autologous viral growth from and infectability of in vitro activated, CD8(+) T cell-depleted CD4(+) T cells from HIV elite controllers (mean viral load,",
keywords = "Humans, Cells, Cultured, CD4-Positive T-Lymphocytes/*immunology/*virology, Virus Replication, Virulence, HIV Infections/*immunology/*virology, *HIV Long-Term Survivors, HIV-1/*immunology/*pathogenicity, Humans, Cells, Cultured, CD4-Positive T-Lymphocytes/*immunology/*virology, Virus Replication, Virulence, HIV Infections/*immunology/*virology, *HIV Long-Term Survivors, HIV-1/*immunology/*pathogenicity",
author = "B Julg and F Pereyra and Buz{\'o}n, {M J} and A Piechocka-Trocha and Clark, {M J} and Baker, {B M} and J Lian and T Miura and J Martinez-Picado and Marylyn Addo and Walker, {B D}",
year = "2010",
language = "English",
volume = "51",
pages = "233--238",
journal = "CLIN INFECT DIS",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers.

AU - Julg, B

AU - Pereyra, F

AU - Buzón, M J

AU - Piechocka-Trocha, A

AU - Clark, M J

AU - Baker, B M

AU - Lian, J

AU - Miura, T

AU - Martinez-Picado, J

AU - Addo, Marylyn

AU - Walker, B D

PY - 2010

Y1 - 2010

N2 - BACKGROUND. Human immunodeficiency virus (HIV) elite controllers are able to control infection with HIV-1 spontaneously to undetectable levels in the absence of antiretroviral therapy, but the mechanisms leading to this phenotype are poorly understood. Although low frequencies of HIV-infected peripheral CD4(+) T cells have been reported in this group, it remains unclear to what extent these are due to viral attenuation, active immune containment, or intracellular host factors that restrict virus replication. METHODS. We assessed proviral DNA levels, autologous viral growth from and infectability of in vitro activated, CD8(+) T cell-depleted CD4(+) T cells from HIV elite controllers (mean viral load,

AB - BACKGROUND. Human immunodeficiency virus (HIV) elite controllers are able to control infection with HIV-1 spontaneously to undetectable levels in the absence of antiretroviral therapy, but the mechanisms leading to this phenotype are poorly understood. Although low frequencies of HIV-infected peripheral CD4(+) T cells have been reported in this group, it remains unclear to what extent these are due to viral attenuation, active immune containment, or intracellular host factors that restrict virus replication. METHODS. We assessed proviral DNA levels, autologous viral growth from and infectability of in vitro activated, CD8(+) T cell-depleted CD4(+) T cells from HIV elite controllers (mean viral load,

KW - Humans

KW - Cells, Cultured

KW - CD4-Positive T-Lymphocytes/immunology/virology

KW - Virus Replication

KW - Virulence

KW - HIV Infections/immunology/virology

KW - HIV Long-Term Survivors

KW - HIV-1/immunology/pathogenicity

KW - Humans

KW - Cells, Cultured

KW - CD4-Positive T-Lymphocytes/immunology/virology

KW - Virus Replication

KW - Virulence

KW - HIV Infections/immunology/virology

KW - HIV Long-Term Survivors

KW - HIV-1/immunology/pathogenicity

M3 - SCORING: Journal article

VL - 51

SP - 233

EP - 238

JO - CLIN INFECT DIS

JF - CLIN INFECT DIS

SN - 1058-4838

IS - 2

M1 - 2

ER -