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Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon

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Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon. / Fürnkranz, Alexander; Bordignon, Stefano; Schmidt, Boris; Gunawardene, Melanie; Schulte-Hahn, Britta; Urban, Verena; Bode, Frank; Nowak, Bernd; Chun, Julian K R.

in: J CARDIOVASC ELECTR, Jahrgang 24, Nr. 5, 01.05.2013, S. 492-7.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Fürnkranz, A, Bordignon, S, Schmidt, B, Gunawardene, M, Schulte-Hahn, B, Urban, V, Bode, F, Nowak, B & Chun, JKR 2013, 'Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon', J CARDIOVASC ELECTR, Jg. 24, Nr. 5, S. 492-7. https://doi.org/10.1111/jce.12082

APA

Fürnkranz, A., Bordignon, S., Schmidt, B., Gunawardene, M., Schulte-Hahn, B., Urban, V., Bode, F., Nowak, B., & Chun, J. K. R. (2013). Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon. J CARDIOVASC ELECTR, 24(5), 492-7. https://doi.org/10.1111/jce.12082

Vancouver

Fürnkranz A, Bordignon S, Schmidt B, Gunawardene M, Schulte-Hahn B, Urban V et al. Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon. J CARDIOVASC ELECTR. 2013 Mai 1;24(5):492-7. https://doi.org/10.1111/jce.12082

Bibtex

@article{16ce9202cb4644058f8dd10567920493,
title = "Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon",
abstract = "INTRODUCTION: The cryoballoon technology has the potential to isolate a pulmonary vein (PV) with a single energy application. However, using the first-generation cryoballoon (CB-1G) repeated freezing or additional focal ablation is often necessary. The novel second-generation cryoballoon (CB-2G) features a widened zone of optimal cooling comprising the whole frontal hemisphere. The aim of this study was to investigate the impact of the novel design on procedural efficacy of cryoballoon PV isolation (CB-PVI).METHODS AND RESULTS: Single transseptal CB-PVI using an endoluminal spiral mapping catheter was performed in 60 consecutive patients (CB-1G, 28 mm, 300 seconds application time: 30 patients; CB-2G, 28 mm, 240 seconds application time: 30 patients). When compared to the CB-1G, using the CB-2G increased single-shot PVI rate from 51% to 84% (P < 0.001) and decreased procedure duration (128 ± 27 vs 98 ± 30 minutes; P < 0.001), and fluoroscopy exposure time (19.5 ± 7.4 vs 13.4 ± 5.3 min; P = 0.001). Effective CB-2G PVI could be performed with increased real-time PVI visualization rate (49% vs 76%; P < 0.001). Time to PVI (T(PVI)) was shorter in the CB-2G group (79 ± 60 vs. 52 ± 36 seconds; P = 0.049). Procedure-related complications occurred in 2 patients in the CB-1G group and 1 patient in the CB-2G group.CONCLUSIONS: The CB-2G significantly improved procedural efficacy compared to the CB-1G and provided reliable T(PVI) measurement. T(PVI) may be used to adjust application time and number individually in future studies. Final conclusions regarding the safety profile of the CB-2G requires additional research.",
keywords = "Aged, Atrial Fibrillation, Catheter Ablation, Cryosurgery, Female, Humans, Male, Middle Aged, Operative Time, Postoperative Care, Postoperative Complications, Pulmonary Veins",
author = "Alexander F{\"u}rnkranz and Stefano Bordignon and Boris Schmidt and Melanie Gunawardene and Britta Schulte-Hahn and Verena Urban and Frank Bode and Bernd Nowak and Chun, {Julian K R}",
note = "{\textcopyright} 2012 Wiley Periodicals, Inc.",
year = "2013",
month = may,
day = "1",
doi = "10.1111/jce.12082",
language = "English",
volume = "24",
pages = "492--7",
journal = "J CARDIOVASC ELECTR",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon

AU - Fürnkranz, Alexander

AU - Bordignon, Stefano

AU - Schmidt, Boris

AU - Gunawardene, Melanie

AU - Schulte-Hahn, Britta

AU - Urban, Verena

AU - Bode, Frank

AU - Nowak, Bernd

AU - Chun, Julian K R

N1 - © 2012 Wiley Periodicals, Inc.

PY - 2013/5/1

Y1 - 2013/5/1

N2 - INTRODUCTION: The cryoballoon technology has the potential to isolate a pulmonary vein (PV) with a single energy application. However, using the first-generation cryoballoon (CB-1G) repeated freezing or additional focal ablation is often necessary. The novel second-generation cryoballoon (CB-2G) features a widened zone of optimal cooling comprising the whole frontal hemisphere. The aim of this study was to investigate the impact of the novel design on procedural efficacy of cryoballoon PV isolation (CB-PVI).METHODS AND RESULTS: Single transseptal CB-PVI using an endoluminal spiral mapping catheter was performed in 60 consecutive patients (CB-1G, 28 mm, 300 seconds application time: 30 patients; CB-2G, 28 mm, 240 seconds application time: 30 patients). When compared to the CB-1G, using the CB-2G increased single-shot PVI rate from 51% to 84% (P < 0.001) and decreased procedure duration (128 ± 27 vs 98 ± 30 minutes; P < 0.001), and fluoroscopy exposure time (19.5 ± 7.4 vs 13.4 ± 5.3 min; P = 0.001). Effective CB-2G PVI could be performed with increased real-time PVI visualization rate (49% vs 76%; P < 0.001). Time to PVI (T(PVI)) was shorter in the CB-2G group (79 ± 60 vs. 52 ± 36 seconds; P = 0.049). Procedure-related complications occurred in 2 patients in the CB-1G group and 1 patient in the CB-2G group.CONCLUSIONS: The CB-2G significantly improved procedural efficacy compared to the CB-1G and provided reliable T(PVI) measurement. T(PVI) may be used to adjust application time and number individually in future studies. Final conclusions regarding the safety profile of the CB-2G requires additional research.

AB - INTRODUCTION: The cryoballoon technology has the potential to isolate a pulmonary vein (PV) with a single energy application. However, using the first-generation cryoballoon (CB-1G) repeated freezing or additional focal ablation is often necessary. The novel second-generation cryoballoon (CB-2G) features a widened zone of optimal cooling comprising the whole frontal hemisphere. The aim of this study was to investigate the impact of the novel design on procedural efficacy of cryoballoon PV isolation (CB-PVI).METHODS AND RESULTS: Single transseptal CB-PVI using an endoluminal spiral mapping catheter was performed in 60 consecutive patients (CB-1G, 28 mm, 300 seconds application time: 30 patients; CB-2G, 28 mm, 240 seconds application time: 30 patients). When compared to the CB-1G, using the CB-2G increased single-shot PVI rate from 51% to 84% (P < 0.001) and decreased procedure duration (128 ± 27 vs 98 ± 30 minutes; P < 0.001), and fluoroscopy exposure time (19.5 ± 7.4 vs 13.4 ± 5.3 min; P = 0.001). Effective CB-2G PVI could be performed with increased real-time PVI visualization rate (49% vs 76%; P < 0.001). Time to PVI (T(PVI)) was shorter in the CB-2G group (79 ± 60 vs. 52 ± 36 seconds; P = 0.049). Procedure-related complications occurred in 2 patients in the CB-1G group and 1 patient in the CB-2G group.CONCLUSIONS: The CB-2G significantly improved procedural efficacy compared to the CB-1G and provided reliable T(PVI) measurement. T(PVI) may be used to adjust application time and number individually in future studies. Final conclusions regarding the safety profile of the CB-2G requires additional research.

KW - Aged

KW - Atrial Fibrillation

KW - Catheter Ablation

KW - Cryosurgery

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Operative Time

KW - Postoperative Care

KW - Postoperative Complications

KW - Pulmonary Veins

U2 - 10.1111/jce.12082

DO - 10.1111/jce.12082

M3 - SCORING: Journal article

C2 - 23398599

VL - 24

SP - 492

EP - 497

JO - J CARDIOVASC ELECTR

JF - J CARDIOVASC ELECTR

SN - 1045-3873

IS - 5

ER -