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Hypoxic liver injury and cholestasis in critically ill patients

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Hypoxic liver injury and cholestasis in critically ill patients. / Horvatits, Thomas; Trauner, Michael; Fuhrmann, Valentin.

in: CURR OPIN CRIT CARE, Jahrgang 19, Nr. 2, 01.04.2013, S. 128-32.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Horvatits, T, Trauner, M & Fuhrmann, V 2013, 'Hypoxic liver injury and cholestasis in critically ill patients', CURR OPIN CRIT CARE, Jg. 19, Nr. 2, S. 128-32. https://doi.org/10.1097/MCC.0b013e32835ec9e6

APA

Horvatits, T., Trauner, M., & Fuhrmann, V. (2013). Hypoxic liver injury and cholestasis in critically ill patients. CURR OPIN CRIT CARE, 19(2), 128-32. https://doi.org/10.1097/MCC.0b013e32835ec9e6

Vancouver

Horvatits T, Trauner M, Fuhrmann V. Hypoxic liver injury and cholestasis in critically ill patients. CURR OPIN CRIT CARE. 2013 Apr 1;19(2):128-32. https://doi.org/10.1097/MCC.0b013e32835ec9e6

Bibtex

@article{5b5d03c6164843e898456eee63bf7ad0,
title = "Hypoxic liver injury and cholestasis in critically ill patients",
abstract = "PURPOSE OF REVIEW: Liver dysfunction frequently complicates the clinical picture of critical illness and leads to increased morbidity and mortality. The purpose of this review is to characterize the most frequent patterns of liver dysfunction at the intensive care unit, cholestasis and hypoxic liver injury (HLI), and to illustrate its clinical impact on outcome in critically ill patients.RECENT FINDINGS: Liver dysfunction at the intensive care unit can be divided into two main patterns: cholestatic and HLI, also known as ischemic hepatitis or shock liver. Both hepatic dysfunctions occur frequently and early in critical illness. Major issues are the early recognition and subsequent initiation of therapeutic measures.SUMMARY: Clinical awareness of the liver not only as a victim, but also as a trigger of multiorgan failure is of central clinical importance. Physicians have to identify the underlying factors that contribute to its development to initiate curative measures as early as possible.",
keywords = "Cardiac Output, Low, Cardiotonic Agents, Cholestasis, Critical Illness, Dobutamine, Early Diagnosis, Female, Fluid Therapy, Humans, Intensive Care Units, Liver Diseases, Male, Multiple Organ Failure, Prognosis",
author = "Thomas Horvatits and Michael Trauner and Valentin Fuhrmann",
year = "2013",
month = apr,
day = "1",
doi = "10.1097/MCC.0b013e32835ec9e6",
language = "English",
volume = "19",
pages = "128--32",
journal = "CURR OPIN CRIT CARE",
issn = "1070-5295",
publisher = "LIPPINCOTT WILLIAMS & WILKINS",
number = "2",

}

RIS

TY - JOUR

T1 - Hypoxic liver injury and cholestasis in critically ill patients

AU - Horvatits, Thomas

AU - Trauner, Michael

AU - Fuhrmann, Valentin

PY - 2013/4/1

Y1 - 2013/4/1

N2 - PURPOSE OF REVIEW: Liver dysfunction frequently complicates the clinical picture of critical illness and leads to increased morbidity and mortality. The purpose of this review is to characterize the most frequent patterns of liver dysfunction at the intensive care unit, cholestasis and hypoxic liver injury (HLI), and to illustrate its clinical impact on outcome in critically ill patients.RECENT FINDINGS: Liver dysfunction at the intensive care unit can be divided into two main patterns: cholestatic and HLI, also known as ischemic hepatitis or shock liver. Both hepatic dysfunctions occur frequently and early in critical illness. Major issues are the early recognition and subsequent initiation of therapeutic measures.SUMMARY: Clinical awareness of the liver not only as a victim, but also as a trigger of multiorgan failure is of central clinical importance. Physicians have to identify the underlying factors that contribute to its development to initiate curative measures as early as possible.

AB - PURPOSE OF REVIEW: Liver dysfunction frequently complicates the clinical picture of critical illness and leads to increased morbidity and mortality. The purpose of this review is to characterize the most frequent patterns of liver dysfunction at the intensive care unit, cholestasis and hypoxic liver injury (HLI), and to illustrate its clinical impact on outcome in critically ill patients.RECENT FINDINGS: Liver dysfunction at the intensive care unit can be divided into two main patterns: cholestatic and HLI, also known as ischemic hepatitis or shock liver. Both hepatic dysfunctions occur frequently and early in critical illness. Major issues are the early recognition and subsequent initiation of therapeutic measures.SUMMARY: Clinical awareness of the liver not only as a victim, but also as a trigger of multiorgan failure is of central clinical importance. Physicians have to identify the underlying factors that contribute to its development to initiate curative measures as early as possible.

KW - Cardiac Output, Low

KW - Cardiotonic Agents

KW - Cholestasis

KW - Critical Illness

KW - Dobutamine

KW - Early Diagnosis

KW - Female

KW - Fluid Therapy

KW - Humans

KW - Intensive Care Units

KW - Liver Diseases

KW - Male

KW - Multiple Organ Failure

KW - Prognosis

U2 - 10.1097/MCC.0b013e32835ec9e6

DO - 10.1097/MCC.0b013e32835ec9e6

M3 - SCORING: Journal article

C2 - 23403733

VL - 19

SP - 128

EP - 132

JO - CURR OPIN CRIT CARE

JF - CURR OPIN CRIT CARE

SN - 1070-5295

IS - 2

ER -