Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.

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Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival. / Deuse, Tobias; Seifert, Martina; Phillips, Neil; Fire, Andrew; Tyan, Dolly; Kay, Mark; Tsao, Philip S; Hua, Xiaoqin; Velden, Joachim; Eiermann, Thomas; Volk, Hans-Dieter; Reichenspurner, Hermann; Robbins, Robert C; Schrepfer, Sonja.

in: CIRCULATION, Jahrgang 124, Nr. 11 Suppl, 11 Suppl, 2011, S. 3-9.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Deuse, T, Seifert, M, Phillips, N, Fire, A, Tyan, D, Kay, M, Tsao, PS, Hua, X, Velden, J, Eiermann, T, Volk, H-D, Reichenspurner, H, Robbins, RC & Schrepfer, S 2011, 'Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.', CIRCULATION, Jg. 124, Nr. 11 Suppl, 11 Suppl, S. 3-9. <http://www.ncbi.nlm.nih.gov/pubmed/21911816?dopt=Citation>

APA

Deuse, T., Seifert, M., Phillips, N., Fire, A., Tyan, D., Kay, M., Tsao, P. S., Hua, X., Velden, J., Eiermann, T., Volk, H-D., Reichenspurner, H., Robbins, R. C., & Schrepfer, S. (2011). Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival. CIRCULATION, 124(11 Suppl), 3-9. [11 Suppl]. http://www.ncbi.nlm.nih.gov/pubmed/21911816?dopt=Citation

Vancouver

Deuse T, Seifert M, Phillips N, Fire A, Tyan D, Kay M et al. Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival. CIRCULATION. 2011;124(11 Suppl):3-9. 11 Suppl.

Bibtex

@article{98a4ee8127f7415085f0b9777022202c,
title = "Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.",
abstract = "Although human embryonic stem cells (hESC) have enormous potential for cell replacement therapy of heart failure, immune rejection of hESC derivatives inevitably would occur after transplantation. We therefore aimed to generate a hypoantigeneic hESC line with improved survival characteristics.",
keywords = "Animals, Humans, Male, Time Factors, Cells, Cultured, Mice, Mice, Inbred BALB C, Mice, Knockout, Models, Animal, Mice, Nude, Mice, SCID, Cell Survival/immunology, Embryonic Stem Cells/cytology/*immunology, *Gene Knockdown Techniques, Graft Survival/*immunology, HLA Antigens/*genetics, Immune Tolerance/*immunology, Immunosuppression, *Stem Cell Transplantation, T-Lymphocytes/immunology, Transplantation, Heterologous/*immunology, Animals, Humans, Male, Time Factors, Cells, Cultured, Mice, Mice, Inbred BALB C, Mice, Knockout, Models, Animal, Mice, Nude, Mice, SCID, Cell Survival/immunology, Embryonic Stem Cells/cytology/*immunology, *Gene Knockdown Techniques, Graft Survival/*immunology, HLA Antigens/*genetics, Immune Tolerance/*immunology, Immunosuppression, *Stem Cell Transplantation, T-Lymphocytes/immunology, Transplantation, Heterologous/*immunology",
author = "Tobias Deuse and Martina Seifert and Neil Phillips and Andrew Fire and Dolly Tyan and Mark Kay and Tsao, {Philip S} and Xiaoqin Hua and Joachim Velden and Thomas Eiermann and Hans-Dieter Volk and Hermann Reichenspurner and Robbins, {Robert C} and Sonja Schrepfer",
year = "2011",
language = "English",
volume = "124",
pages = "3--9",
journal = "CIRCULATION",
issn = "0009-7322",
publisher = "Lippincott Williams and Wilkins",
number = "11 Suppl",

}

RIS

TY - JOUR

T1 - Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.

AU - Deuse, Tobias

AU - Seifert, Martina

AU - Phillips, Neil

AU - Fire, Andrew

AU - Tyan, Dolly

AU - Kay, Mark

AU - Tsao, Philip S

AU - Hua, Xiaoqin

AU - Velden, Joachim

AU - Eiermann, Thomas

AU - Volk, Hans-Dieter

AU - Reichenspurner, Hermann

AU - Robbins, Robert C

AU - Schrepfer, Sonja

PY - 2011

Y1 - 2011

N2 - Although human embryonic stem cells (hESC) have enormous potential for cell replacement therapy of heart failure, immune rejection of hESC derivatives inevitably would occur after transplantation. We therefore aimed to generate a hypoantigeneic hESC line with improved survival characteristics.

AB - Although human embryonic stem cells (hESC) have enormous potential for cell replacement therapy of heart failure, immune rejection of hESC derivatives inevitably would occur after transplantation. We therefore aimed to generate a hypoantigeneic hESC line with improved survival characteristics.

KW - Animals

KW - Humans

KW - Male

KW - Time Factors

KW - Cells, Cultured

KW - Mice

KW - Mice, Inbred BALB C

KW - Mice, Knockout

KW - Models, Animal

KW - Mice, Nude

KW - Mice, SCID

KW - Cell Survival/immunology

KW - Embryonic Stem Cells/cytology/immunology

KW - Gene Knockdown Techniques

KW - Graft Survival/immunology

KW - HLA Antigens/genetics

KW - Immune Tolerance/immunology

KW - Immunosuppression

KW - Stem Cell Transplantation

KW - T-Lymphocytes/immunology

KW - Transplantation, Heterologous/immunology

KW - Animals

KW - Humans

KW - Male

KW - Time Factors

KW - Cells, Cultured

KW - Mice

KW - Mice, Inbred BALB C

KW - Mice, Knockout

KW - Models, Animal

KW - Mice, Nude

KW - Mice, SCID

KW - Cell Survival/immunology

KW - Embryonic Stem Cells/cytology/immunology

KW - Gene Knockdown Techniques

KW - Graft Survival/immunology

KW - HLA Antigens/genetics

KW - Immune Tolerance/immunology

KW - Immunosuppression

KW - Stem Cell Transplantation

KW - T-Lymphocytes/immunology

KW - Transplantation, Heterologous/immunology

M3 - SCORING: Journal article

VL - 124

SP - 3

EP - 9

JO - CIRCULATION

JF - CIRCULATION

SN - 0009-7322

IS - 11 Suppl

M1 - 11 Suppl

ER -