Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures.
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Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures. / Karn, Thomas; Pusztai, Lajos; Holtrich, Uwe; Iwamoto, Takayuki; Shiang, Christine Y; Schmidt, Marcus; Müller, Volkmar; Solbach, Christine; Gaetje, Regine; Hanker, Lars; Ahr, Andre; Liedtke, Cornelia; Ruckhäberle, Eugen; Kaufmann, Manfred; Rody, Achim.
in: PLOS ONE, Jahrgang 6, Nr. 12, 12, 2011, S. 28403.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures.
AU - Karn, Thomas
AU - Pusztai, Lajos
AU - Holtrich, Uwe
AU - Iwamoto, Takayuki
AU - Shiang, Christine Y
AU - Schmidt, Marcus
AU - Müller, Volkmar
AU - Solbach, Christine
AU - Gaetje, Regine
AU - Hanker, Lars
AU - Ahr, Andre
AU - Liedtke, Cornelia
AU - Ruckhäberle, Eugen
AU - Kaufmann, Manfred
AU - Rody, Achim
PY - 2011
Y1 - 2011
N2 - Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers. The identification of prognostic signatures from TNBC cohorts was limited in the past due to small sample sizes.
AB - Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers. The identification of prognostic signatures from TNBC cohorts was limited in the past due to small sample sizes.
KW - Humans
KW - Female
KW - Cohort Studies
KW - Reproducibility of Results
KW - Predictive Value of Tests
KW - Prognosis
KW - Tumor Markers, Biological
KW - Neoadjuvant Therapy
KW - Gene Expression Regulation, Neoplastic
KW - Kaplan-Meier Estimate
KW - Gene Expression Profiling
KW - Breast Neoplasms/drug therapy/genetics
KW - Databases, Genetic
KW - Genes, Neoplasm/genetics
KW - Receptor, erbB-2/deficiency/metabolism
KW - Receptors, Estrogen/deficiency/metabolism
KW - Receptors, Progesterone/deficiency/metabolism
KW - Humans
KW - Female
KW - Cohort Studies
KW - Reproducibility of Results
KW - Predictive Value of Tests
KW - Prognosis
KW - Tumor Markers, Biological
KW - Neoadjuvant Therapy
KW - Gene Expression Regulation, Neoplastic
KW - Kaplan-Meier Estimate
KW - Gene Expression Profiling
KW - Breast Neoplasms/drug therapy/genetics
KW - Databases, Genetic
KW - Genes, Neoplasm/genetics
KW - Receptor, erbB-2/deficiency/metabolism
KW - Receptors, Estrogen/deficiency/metabolism
KW - Receptors, Progesterone/deficiency/metabolism
U2 - 10.1371/journal.pone.0028403
DO - 10.1371/journal.pone.0028403
M3 - SCORING: Journal article
VL - 6
SP - 28403
JO - PLOS ONE
JF - PLOS ONE
SN - 1932-6203
IS - 12
M1 - 12
ER -