Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures.

Thomas Karn; Lajos Pusztai; Uwe Holtrich; Takayuki Iwamoto; Christine Y Shiang; Marcus Schmidt; Volkmar Müller; Christine Solbach; Regine Gaetje; Lars Hanker; Andre Ahr; Cornelia Liedtke; Eugen Ruckhäberle; Manfred Kaufmann; Achim Rody

doi:10.1371/journal.pone.0028403

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures.

Thomas Karn
Lajos Pusztai
Uwe Holtrich
Takayuki Iwamoto
Christine Y Shiang
Marcus Schmidt
Volkmar Müller
Christine Solbach
Regine Gaetje
Lars Hanker
Andre Ahr
Cornelia Liedtke
Eugen Ruckhäberle
Manfred Kaufmann
Achim Rody

Beteiligte Einrichtungen

Klinik und Poliklinik für Gynäkologie

Abstract

Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers. The identification of prognostic signatures from TNBC cohorts was limited in the past due to small sample sizes.

Bibliografische Daten

Originalsprache	Englisch
Aufsatznummer	12
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0028403
Status	Veröffentlicht - 2011

pubmed	22220191