PortalPublikationenHMGB1: a two-headed signal regulating tumor progression and ...

HMGB1: a two-headed signal regulating tumor progression and immunity

Standard

HMGB1: a two-headed signal regulating tumor progression and immunity. / Campana, L.; Bosurgi, L.; Rovere-Querini, P.

in: CURR OPIN IMMUNOL, Jahrgang 20, Nr. 5, 2008, S. 518-523.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Campana, L, Bosurgi, L & Rovere-Querini, P 2008, 'HMGB1: a two-headed signal regulating tumor progression and immunity', CURR OPIN IMMUNOL, Jg. 20, Nr. 5, S. 518-523. https://doi.org/10.1016/j.coi.2008.04.012

APA

Campana, L., Bosurgi, L., & Rovere-Querini, P. (2008). HMGB1: a two-headed signal regulating tumor progression and immunity. CURR OPIN IMMUNOL, 20(5), 518-523. https://doi.org/10.1016/j.coi.2008.04.012

Vancouver

Campana L, Bosurgi L, Rovere-Querini P. HMGB1: a two-headed signal regulating tumor progression and immunity. CURR OPIN IMMUNOL. 2008;20(5):518-523. https://doi.org/10.1016/j.coi.2008.04.012

Bibtex

@article{58c896c7c49c4b7985ed2abb330411a9,
title = "HMGB1: a two-headed signal regulating tumor progression and immunity",
abstract = "Cells of the innate immune system sense tissue damage recognizing in the extracellular environment bona fide intracellular moieties, like high mobility group box 1 (HMGB1). In the case of tumors, HMGB1 recognition has a paradoxical dual effect: it promotes tumor neoangiogenesis and triggers protective anti-neoplastic T-cell responses. Recent advances in the study of HMGB1 have identified candidate molecular mechanisms underlying these apparently contrasting outcomes. A surprising role for innate receptors, including toll like receptor 4 (TLR4), in the response to conventional cancer radio and chemotherapy has also recently emerged, providing new insight into the mechanisms by which these treatments actually work.",
author = "L. Campana and L. Bosurgi and P. Rovere-Querini",
year = "2008",
doi = "10.1016/j.coi.2008.04.012",
language = "English",
volume = "20",
pages = "518--523",
number = "5",

}

RIS

TY - JOUR

T1 - HMGB1: a two-headed signal regulating tumor progression and immunity

AU - Campana, L.

AU - Bosurgi, L.

AU - Rovere-Querini, P.

PY - 2008

Y1 - 2008

N2 - Cells of the innate immune system sense tissue damage recognizing in the extracellular environment bona fide intracellular moieties, like high mobility group box 1 (HMGB1). In the case of tumors, HMGB1 recognition has a paradoxical dual effect: it promotes tumor neoangiogenesis and triggers protective anti-neoplastic T-cell responses. Recent advances in the study of HMGB1 have identified candidate molecular mechanisms underlying these apparently contrasting outcomes. A surprising role for innate receptors, including toll like receptor 4 (TLR4), in the response to conventional cancer radio and chemotherapy has also recently emerged, providing new insight into the mechanisms by which these treatments actually work.

AB - Cells of the innate immune system sense tissue damage recognizing in the extracellular environment bona fide intracellular moieties, like high mobility group box 1 (HMGB1). In the case of tumors, HMGB1 recognition has a paradoxical dual effect: it promotes tumor neoangiogenesis and triggers protective anti-neoplastic T-cell responses. Recent advances in the study of HMGB1 have identified candidate molecular mechanisms underlying these apparently contrasting outcomes. A surprising role for innate receptors, including toll like receptor 4 (TLR4), in the response to conventional cancer radio and chemotherapy has also recently emerged, providing new insight into the mechanisms by which these treatments actually work.

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-50549094596&partnerID=MN8TOARS

U2 - 10.1016/j.coi.2008.04.012

DO - 10.1016/j.coi.2008.04.012

M3 - SCORING: Review article

C2 - 18599281

VL - 20

SP - 518

EP - 523

IS - 5

ER -