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Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates

Standard

Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates. / Yasinska, Inna M; Ceccone, Giacomo; Ojea-Jimenez, Isaac; Ponti, Jessica; Hussain, Rohanah; Siligardi, Giuliano; Berger, Steffen M; Fasler-Kan, Elizaveta; Bardelli, Marco; Varani, Luca; Fiedler, Walter; Wellbrock, Jasmin; Raap, Ulrike; Gibbs, Bernhard F; Calzolai, Luigi; Sumbayev, Vadim V.

in: NANOSCALE, Jahrgang 10, Nr. 13, 29.03.2018, S. 5827-5833.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Yasinska, IM, Ceccone, G, Ojea-Jimenez, I, Ponti, J, Hussain, R, Siligardi, G, Berger, SM, Fasler-Kan, E, Bardelli, M, Varani, L, Fiedler, W, Wellbrock, J, Raap, U, Gibbs, BF, Calzolai, L & Sumbayev, VV 2018, 'Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates', NANOSCALE, Jg. 10, Nr. 13, S. 5827-5833. https://doi.org/10.1039/c7nr09436a

APA

Yasinska, I. M., Ceccone, G., Ojea-Jimenez, I., Ponti, J., Hussain, R., Siligardi, G., Berger, S. M., Fasler-Kan, E., Bardelli, M., Varani, L., Fiedler, W., Wellbrock, J., Raap, U., Gibbs, B. F., Calzolai, L., & Sumbayev, V. V. (2018). Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates. NANOSCALE, 10(13), 5827-5833. https://doi.org/10.1039/c7nr09436a

Vancouver

Yasinska IM, Ceccone G, Ojea-Jimenez I, Ponti J, Hussain R, Siligardi G et al. Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates. NANOSCALE. 2018 Mär 29;10(13):5827-5833. https://doi.org/10.1039/c7nr09436a

Bibtex

@article{588469bae12442a187866300936665d9,
title = "Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates",
abstract = "In this study we used 5 nm gold nanoparticles as delivery platforms to target cancer cells expressing the immune receptor Tim-3 using single chain antibodies. Gold surfaces were also covered with the cytotoxic drug rapamycin which was immobilised using a glutathione linker. These nanoconjugates allowed highly specific and efficient delivery of cytotoxic rapamycin into human malignant blood cells.",
keywords = "Journal Article",
author = "Yasinska, {Inna M} and Giacomo Ceccone and Isaac Ojea-Jimenez and Jessica Ponti and Rohanah Hussain and Giuliano Siligardi and Berger, {Steffen M} and Elizaveta Fasler-Kan and Marco Bardelli and Luca Varani and Walter Fiedler and Jasmin Wellbrock and Ulrike Raap and Gibbs, {Bernhard F} and Luigi Calzolai and Sumbayev, {Vadim V}",
year = "2018",
month = mar,
day = "29",
doi = "10.1039/c7nr09436a",
language = "English",
volume = "10",
pages = "5827--5833",
journal = "NANOSCALE",
issn = "2040-3364",
publisher = "Royal Society of Chemistry",
number = "13",

}

RIS

TY - JOUR

T1 - Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates

AU - Yasinska, Inna M

AU - Ceccone, Giacomo

AU - Ojea-Jimenez, Isaac

AU - Ponti, Jessica

AU - Hussain, Rohanah

AU - Siligardi, Giuliano

AU - Berger, Steffen M

AU - Fasler-Kan, Elizaveta

AU - Bardelli, Marco

AU - Varani, Luca

AU - Fiedler, Walter

AU - Wellbrock, Jasmin

AU - Raap, Ulrike

AU - Gibbs, Bernhard F

AU - Calzolai, Luigi

AU - Sumbayev, Vadim V

PY - 2018/3/29

Y1 - 2018/3/29

N2 - In this study we used 5 nm gold nanoparticles as delivery platforms to target cancer cells expressing the immune receptor Tim-3 using single chain antibodies. Gold surfaces were also covered with the cytotoxic drug rapamycin which was immobilised using a glutathione linker. These nanoconjugates allowed highly specific and efficient delivery of cytotoxic rapamycin into human malignant blood cells.

AB - In this study we used 5 nm gold nanoparticles as delivery platforms to target cancer cells expressing the immune receptor Tim-3 using single chain antibodies. Gold surfaces were also covered with the cytotoxic drug rapamycin which was immobilised using a glutathione linker. These nanoconjugates allowed highly specific and efficient delivery of cytotoxic rapamycin into human malignant blood cells.

KW - Journal Article

U2 - 10.1039/c7nr09436a

DO - 10.1039/c7nr09436a

M3 - SCORING: Journal article

C2 - 29538473

VL - 10

SP - 5827

EP - 5833

JO - NANOSCALE

JF - NANOSCALE

SN - 2040-3364

IS - 13

ER -