Hepatic vasculopathy and regenerative responses of the liver in fatal cases of COVID-19

  • Barbara Kaltschmidt (Geteilte/r Erstautor/in)
  • Antonia D E Fitzek (Geteilte/r Erstautor/in)
  • Julia Schaedler (Geteilte/r Erstautor/in)
  • Christine Förster (Geteilte/r Erstautor/in)
  • Christian Kaltschmidt
  • Thorsten Hansen
  • Fabian Steinfurth
  • Beatrice A Windmöller
  • Christian Pilger
  • Cihang Kong
  • Kashika Singh
  • Axel Nierhaus
  • Dominic Wichmann
  • Jan Sperhake
  • Klaus Püschel
  • Thomas Huser
  • Martin Krüger (Geteilte/r Letztautor/in)
  • Simon C Robson (Geteilte/r Letztautor/in)
  • Ludwig Wilkens (Geteilte/r Letztautor/in)
  • Jan Schulte Am Esch (Geteilte/r Letztautor/in)

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects the nasopharynx and lungs and causes coronavirus disease-2019 (COVID-19). It may impact the heart, brain, kidney, and liver.1 Although functional impairment of the liver has been correlated with worse clinical outcomes, little is known about the pathophysiology of hepatic injury and repair in COVID-19.2,3 Histologic evaluation has been limited to small numbers of COVID-19 cases with no control subjects2,4 and demonstrated largely heterogeneous patterns of pathology.2,3.

Bibliografische Daten

OriginalspracheEnglisch
ISSN1542-3565
DOIs
StatusVeröffentlicht - 08.2021
PubMed 33516952