Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.

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Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients. / Schwarzenbach, Heidi; Chun, Felix; Isbarn, Hendrik; Huland, Hartwig; Pantel, Klaus.

in: J CANCER RES CLIN, Jahrgang 137, Nr. 5, 5, 2011, S. 811-819.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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Bibtex

@article{dad769669f0e432b929ad4cb6e1ddcb9,
title = "Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.",
abstract = "To advance the characterization of tumor-associated cell-free DNA in blood and bone marrow (BM), a rapid profiling method using methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) was established. MS-MLPA detects genetic and epigenetic aberrations of 37 tumor suppressor genes (TSG) in a single reaction and might, therefore, avoid the cumbersome single gene analyses.",
author = "Heidi Schwarzenbach and Felix Chun and Hendrik Isbarn and Hartwig Huland and Klaus Pantel",
year = "2011",
language = "English",
volume = "137",
pages = "811--819",
journal = "J CANCER RES CLIN",
issn = "0171-5216",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.

AU - Schwarzenbach, Heidi

AU - Chun, Felix

AU - Isbarn, Hendrik

AU - Huland, Hartwig

AU - Pantel, Klaus

PY - 2011

Y1 - 2011

N2 - To advance the characterization of tumor-associated cell-free DNA in blood and bone marrow (BM), a rapid profiling method using methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) was established. MS-MLPA detects genetic and epigenetic aberrations of 37 tumor suppressor genes (TSG) in a single reaction and might, therefore, avoid the cumbersome single gene analyses.

AB - To advance the characterization of tumor-associated cell-free DNA in blood and bone marrow (BM), a rapid profiling method using methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) was established. MS-MLPA detects genetic and epigenetic aberrations of 37 tumor suppressor genes (TSG) in a single reaction and might, therefore, avoid the cumbersome single gene analyses.

M3 - SCORING: Journal article

VL - 137

SP - 811

EP - 819

JO - J CANCER RES CLIN

JF - J CANCER RES CLIN

SN - 0171-5216

IS - 5

M1 - 5

ER -