Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.
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Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients. / Schwarzenbach, Heidi; Chun, Felix; Isbarn, Hendrik; Huland, Hartwig; Pantel, Klaus.
in: J CANCER RES CLIN, Jahrgang 137, Nr. 5, 5, 2011, S. 811-819.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.
AU - Schwarzenbach, Heidi
AU - Chun, Felix
AU - Isbarn, Hendrik
AU - Huland, Hartwig
AU - Pantel, Klaus
PY - 2011
Y1 - 2011
N2 - To advance the characterization of tumor-associated cell-free DNA in blood and bone marrow (BM), a rapid profiling method using methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) was established. MS-MLPA detects genetic and epigenetic aberrations of 37 tumor suppressor genes (TSG) in a single reaction and might, therefore, avoid the cumbersome single gene analyses.
AB - To advance the characterization of tumor-associated cell-free DNA in blood and bone marrow (BM), a rapid profiling method using methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) was established. MS-MLPA detects genetic and epigenetic aberrations of 37 tumor suppressor genes (TSG) in a single reaction and might, therefore, avoid the cumbersome single gene analyses.
M3 - SCORING: Journal article
VL - 137
SP - 811
EP - 819
JO - J CANCER RES CLIN
JF - J CANCER RES CLIN
SN - 0171-5216
IS - 5
M1 - 5
ER -