Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.
Beteiligte Einrichtungen
Abstract
To advance the characterization of tumor-associated cell-free DNA in blood and bone marrow (BM), a rapid profiling method using methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) was established. MS-MLPA detects genetic and epigenetic aberrations of 37 tumor suppressor genes (TSG) in a single reaction and might, therefore, avoid the cumbersome single gene analyses.
Bibliografische Daten
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 5 |
| ISSN | 0171-5216 |
| Status | Veröffentlicht - 2011 |
| pubmed | 20683729 |
|---|
