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FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency

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FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency. / Peiseler, Moritz; Sebode, Marcial; Franke, Björn; Wortmann, Frederike; Schwinge, Dorothee; Quaas, Alexander; Baron, Udo; Olek, Sven; Wiegard, Christiane; Lohse, Ansgar W.; Weiler-Normann, Christina; Schramm, Christoph; Herkel, Johannes.

in: J HEPATOL, Jahrgang 57, Nr. 1, 1, 07.2012, S. 125-132.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Peiseler, M, Sebode, M, Franke, B, Wortmann, F, Schwinge, D, Quaas, A, Baron, U, Olek, S, Wiegard, C, Lohse, AW, Weiler-Normann, C, Schramm, C & Herkel, J 2012, 'FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency', J HEPATOL, Jg. 57, Nr. 1, 1, S. 125-132. https://doi.org/10.1016/j.jhep.2012.02.029

APA

Peiseler, M., Sebode, M., Franke, B., Wortmann, F., Schwinge, D., Quaas, A., Baron, U., Olek, S., Wiegard, C., Lohse, A. W., Weiler-Normann, C., Schramm, C., & Herkel, J. (2012). FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency. J HEPATOL, 57(1), 125-132. [1]. https://doi.org/10.1016/j.jhep.2012.02.029

Vancouver

Peiseler M, Sebode M, Franke B, Wortmann F, Schwinge D, Quaas A et al. FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency. J HEPATOL. 2012 Jul;57(1):125-132. 1. https://doi.org/10.1016/j.jhep.2012.02.029

Bibtex

@article{af905909362e4ce4b46c8caad841b9ba,
title = "FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency",
abstract = "The pathogenesis of autoimmune hepatitis (AIH) is not understood, but it was suggested that AIH may be related to a numerical or functional impairment of CD4+CD25+FOXP3+ regulatory T cells (Treg), which are important mediators of immune tolerance to self-antigens. However, the role of Treg in AIH is not clear, since earlier studies reporting Treg impairment had used only CD25 as marker that cannot unambiguously distinguish Treg from activated effector T cells.",
keywords = "Adolescent, Adult, Aged, CD4 Antigens, Female, Flow Cytometry, Forkhead Transcription Factors, Hepatitis, Autoimmune, Humans, Interleukin-2 Receptor alpha Subunit, Lymphocyte Activation, Lymphocyte Count, Male, Middle Aged, T-Lymphocytes, Regulatory, Young Adult, Journal Article, Research Support, Non-U.S. Gov't",
author = "Moritz Peiseler and Marcial Sebode and Bj{\"o}rn Franke and Frederike Wortmann and Dorothee Schwinge and Alexander Quaas and Udo Baron and Sven Olek and Christiane Wiegard and Lohse, {Ansgar W.} and Christina Weiler-Normann and Christoph Schramm and Johannes Herkel",
note = "Copyright {\textcopyright} 2012 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.",
year = "2012",
month = jul,
doi = "10.1016/j.jhep.2012.02.029",
language = "English",
volume = "57",
pages = "125--132",
journal = "J HEPATOL",
issn = "0168-8278",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency

AU - Peiseler, Moritz

AU - Sebode, Marcial

AU - Franke, Björn

AU - Wortmann, Frederike

AU - Schwinge, Dorothee

AU - Quaas, Alexander

AU - Baron, Udo

AU - Olek, Sven

AU - Wiegard, Christiane

AU - Lohse, Ansgar W.

AU - Weiler-Normann, Christina

AU - Schramm, Christoph

AU - Herkel, Johannes

N1 - Copyright © 2012 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

PY - 2012/7

Y1 - 2012/7

N2 - The pathogenesis of autoimmune hepatitis (AIH) is not understood, but it was suggested that AIH may be related to a numerical or functional impairment of CD4+CD25+FOXP3+ regulatory T cells (Treg), which are important mediators of immune tolerance to self-antigens. However, the role of Treg in AIH is not clear, since earlier studies reporting Treg impairment had used only CD25 as marker that cannot unambiguously distinguish Treg from activated effector T cells.

AB - The pathogenesis of autoimmune hepatitis (AIH) is not understood, but it was suggested that AIH may be related to a numerical or functional impairment of CD4+CD25+FOXP3+ regulatory T cells (Treg), which are important mediators of immune tolerance to self-antigens. However, the role of Treg in AIH is not clear, since earlier studies reporting Treg impairment had used only CD25 as marker that cannot unambiguously distinguish Treg from activated effector T cells.

KW - Adolescent

KW - Adult

KW - Aged

KW - CD4 Antigens

KW - Female

KW - Flow Cytometry

KW - Forkhead Transcription Factors

KW - Hepatitis, Autoimmune

KW - Humans

KW - Interleukin-2 Receptor alpha Subunit

KW - Lymphocyte Activation

KW - Lymphocyte Count

KW - Male

KW - Middle Aged

KW - T-Lymphocytes, Regulatory

KW - Young Adult

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1016/j.jhep.2012.02.029

DO - 10.1016/j.jhep.2012.02.029

M3 - SCORING: Journal article

C2 - 22425700

VL - 57

SP - 125

EP - 132

JO - J HEPATOL

JF - J HEPATOL

SN - 0168-8278

IS - 1

M1 - 1

ER -