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Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws

Standard

Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws. / Pautke, Christoph; Bauer, Florian; Tischer, Thomas; Kreutzer, Kilian; Weitz, Jochen; Kesting, Marco; Hölzle, Frank; Kolk, Andreas; Stürzenbaum, Stephen R; Wolff, Klaus-Dietrich.

in: J ORAL MAXIL SURG, Jahrgang 67, Nr. 3, 03.2009, S. 471-6.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Pautke, C, Bauer, F, Tischer, T, Kreutzer, K, Weitz, J, Kesting, M, Hölzle, F, Kolk, A, Stürzenbaum, SR & Wolff, K-D 2009, 'Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws', J ORAL MAXIL SURG, Jg. 67, Nr. 3, S. 471-6. https://doi.org/10.1016/j.joms.2008.09.037

APA

Pautke, C., Bauer, F., Tischer, T., Kreutzer, K., Weitz, J., Kesting, M., Hölzle, F., Kolk, A., Stürzenbaum, S. R., & Wolff, K-D. (2009). Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws. J ORAL MAXIL SURG, 67(3), 471-6. https://doi.org/10.1016/j.joms.2008.09.037

Vancouver

Pautke C, Bauer F, Tischer T, Kreutzer K, Weitz J, Kesting M et al. Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws. J ORAL MAXIL SURG. 2009 Mär;67(3):471-6. https://doi.org/10.1016/j.joms.2008.09.037

Bibtex

@article{4a695cb4f362453c96ea40dd27482484,
title = "Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws",
abstract = "PURPOSE: To date, the therapy of bisphosphonate-associated osteonecrosis of the jaws (BONJ) has been hampered by the lack of imaging modalities that enable the extent of necrosis to be visualized. This study aims to demonstrate the feasibility of tetracycline fluorescence guided bone resection in the surgical management of BONJ.PATIENTS AND METHODS: Following a 10-day preoperative administration of doxycycline in patients suffering from BONJ, sufficient doxycycline is incorporated into viable bone to be visualized with a certified medical lamp emitting exciting light at 400 to 460 nm.RESULTS: Viable and necrotic bone can be discriminated intraoperatively in a routine and reproducible manner by doxycycline bone fluorescence.CONCLUSION: In the therapy of BONJ, conservative concepts are to be favored. The fact that necrotic bone can now be selectively resected signifies an improvement of the conservative surgical therapy of BONJ.",
keywords = "Aged, Bone Density Conservation Agents, Cone-Beam Computed Tomography, Diphosphonates, Feasibility Studies, Female, Fluorescence, Fluorometry, Humans, Jaw, Jaw Diseases, Light, Male, Oral Surgical Procedures, Osteonecrosis, Tetracycline",
author = "Christoph Pautke and Florian Bauer and Thomas Tischer and Kilian Kreutzer and Jochen Weitz and Marco Kesting and Frank H{\"o}lzle and Andreas Kolk and St{\"u}rzenbaum, {Stephen R} and Klaus-Dietrich Wolff",
year = "2009",
month = mar,
doi = "10.1016/j.joms.2008.09.037",
language = "English",
volume = "67",
pages = "471--6",
journal = "J ORAL MAXIL SURG",
issn = "0278-2391",
publisher = "W.B. Saunders Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws

AU - Pautke, Christoph

AU - Bauer, Florian

AU - Tischer, Thomas

AU - Kreutzer, Kilian

AU - Weitz, Jochen

AU - Kesting, Marco

AU - Hölzle, Frank

AU - Kolk, Andreas

AU - Stürzenbaum, Stephen R

AU - Wolff, Klaus-Dietrich

PY - 2009/3

Y1 - 2009/3

N2 - PURPOSE: To date, the therapy of bisphosphonate-associated osteonecrosis of the jaws (BONJ) has been hampered by the lack of imaging modalities that enable the extent of necrosis to be visualized. This study aims to demonstrate the feasibility of tetracycline fluorescence guided bone resection in the surgical management of BONJ.PATIENTS AND METHODS: Following a 10-day preoperative administration of doxycycline in patients suffering from BONJ, sufficient doxycycline is incorporated into viable bone to be visualized with a certified medical lamp emitting exciting light at 400 to 460 nm.RESULTS: Viable and necrotic bone can be discriminated intraoperatively in a routine and reproducible manner by doxycycline bone fluorescence.CONCLUSION: In the therapy of BONJ, conservative concepts are to be favored. The fact that necrotic bone can now be selectively resected signifies an improvement of the conservative surgical therapy of BONJ.

AB - PURPOSE: To date, the therapy of bisphosphonate-associated osteonecrosis of the jaws (BONJ) has been hampered by the lack of imaging modalities that enable the extent of necrosis to be visualized. This study aims to demonstrate the feasibility of tetracycline fluorescence guided bone resection in the surgical management of BONJ.PATIENTS AND METHODS: Following a 10-day preoperative administration of doxycycline in patients suffering from BONJ, sufficient doxycycline is incorporated into viable bone to be visualized with a certified medical lamp emitting exciting light at 400 to 460 nm.RESULTS: Viable and necrotic bone can be discriminated intraoperatively in a routine and reproducible manner by doxycycline bone fluorescence.CONCLUSION: In the therapy of BONJ, conservative concepts are to be favored. The fact that necrotic bone can now be selectively resected signifies an improvement of the conservative surgical therapy of BONJ.

KW - Aged

KW - Bone Density Conservation Agents

KW - Cone-Beam Computed Tomography

KW - Diphosphonates

KW - Feasibility Studies

KW - Female

KW - Fluorescence

KW - Fluorometry

KW - Humans

KW - Jaw

KW - Jaw Diseases

KW - Light

KW - Male

KW - Oral Surgical Procedures

KW - Osteonecrosis

KW - Tetracycline

U2 - 10.1016/j.joms.2008.09.037

DO - 10.1016/j.joms.2008.09.037

M3 - SCORING: Journal article

C2 - 19231768

VL - 67

SP - 471

EP - 476

JO - J ORAL MAXIL SURG

JF - J ORAL MAXIL SURG

SN - 0278-2391

IS - 3

ER -