PortalPublikationenEvaluation of cartilage specific matrix synthesis of human a...

Evaluation of cartilage specific matrix synthesis of human articular chondrocytes after extended propagation on microcarriers by image analysis.

Standard

Evaluation of cartilage specific matrix synthesis of human articular chondrocytes after extended propagation on microcarriers by image analysis. / Goepfert, Christiane; Lutz, Vivien; Lünse, Svenja; Kittel, Sabrina; Wiegandt, Katharina; Kammal, Michael; Püschel, Klaus; Pörtner, Ralf.

in: INT J ARTIF ORGANS, Jahrgang 33, Nr. 4, 4, 2010, S. 204-218.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Goepfert, C, Lutz, V, Lünse, S, Kittel, S, Wiegandt, K, Kammal, M, Püschel, K & Pörtner, R 2010, 'Evaluation of cartilage specific matrix synthesis of human articular chondrocytes after extended propagation on microcarriers by image analysis.', INT J ARTIF ORGANS, Jg. 33, Nr. 4, 4, S. 204-218. <http://www.ncbi.nlm.nih.gov/pubmed/20458690?dopt=Citation>

APA

Goepfert, C., Lutz, V., Lünse, S., Kittel, S., Wiegandt, K., Kammal, M., Püschel, K., & Pörtner, R. (2010). Evaluation of cartilage specific matrix synthesis of human articular chondrocytes after extended propagation on microcarriers by image analysis. INT J ARTIF ORGANS, 33(4), 204-218. [4]. http://www.ncbi.nlm.nih.gov/pubmed/20458690?dopt=Citation

Vancouver

Goepfert C, Lutz V, Lünse S, Kittel S, Wiegandt K, Kammal M et al. Evaluation of cartilage specific matrix synthesis of human articular chondrocytes after extended propagation on microcarriers by image analysis. INT J ARTIF ORGANS. 2010;33(4):204-218. 4.

Bibtex

@article{2748754e55614b039e4d777a181b1c8a,
title = "Evaluation of cartilage specific matrix synthesis of human articular chondrocytes after extended propagation on microcarriers by image analysis.",
abstract = "Cell-based technologies for the repair of cartilage defects usually rely on the expansion of low numbers of chondrocytes isolated from biopsies of healthy cartilage. Proliferating chondrocytes are known to undergo dedifferentiation characterized by downregulation of collagen type II and proteoglycan production, and by upregulation of collagen type I synthesis. Re-expression of cartilage specific matrix components by expanded chondrocytes is therefore critical for successful cartilage repair.",
keywords = "Humans, Transforming Growth Factor beta pharmacology, Image Processing, Computer-Assisted, Cell Differentiation physiology, Tissue Engineering methods, Insulin-Like Growth Factor I pharmacology, Bone Morphogenetic Protein 7 pharmacology, Cartilage, Articular cytology, Chondrocytes metabolism, Collagen drug effects, Collagen Type II metabolism, Humans, Transforming Growth Factor beta pharmacology, Image Processing, Computer-Assisted, Cell Differentiation physiology, Tissue Engineering methods, Insulin-Like Growth Factor I pharmacology, Bone Morphogenetic Protein 7 pharmacology, Cartilage, Articular cytology, Chondrocytes metabolism, Collagen drug effects, Collagen Type II metabolism",
author = "Christiane Goepfert and Vivien Lutz and Svenja L{\"u}nse and Sabrina Kittel and Katharina Wiegandt and Michael Kammal and Klaus P{\"u}schel and Ralf P{\"o}rtner",
year = "2010",
language = "Deutsch",
volume = "33",
pages = "204--218",
journal = "INT J ARTIF ORGANS",
issn = "0391-3988",
publisher = "Wichtig Publishing",
number = "4",

}

RIS

TY - JOUR

T1 - Evaluation of cartilage specific matrix synthesis of human articular chondrocytes after extended propagation on microcarriers by image analysis.

AU - Goepfert, Christiane

AU - Lutz, Vivien

AU - Lünse, Svenja

AU - Kittel, Sabrina

AU - Wiegandt, Katharina

AU - Kammal, Michael

AU - Püschel, Klaus

AU - Pörtner, Ralf

PY - 2010

Y1 - 2010

N2 - Cell-based technologies for the repair of cartilage defects usually rely on the expansion of low numbers of chondrocytes isolated from biopsies of healthy cartilage. Proliferating chondrocytes are known to undergo dedifferentiation characterized by downregulation of collagen type II and proteoglycan production, and by upregulation of collagen type I synthesis. Re-expression of cartilage specific matrix components by expanded chondrocytes is therefore critical for successful cartilage repair.

AB - Cell-based technologies for the repair of cartilage defects usually rely on the expansion of low numbers of chondrocytes isolated from biopsies of healthy cartilage. Proliferating chondrocytes are known to undergo dedifferentiation characterized by downregulation of collagen type II and proteoglycan production, and by upregulation of collagen type I synthesis. Re-expression of cartilage specific matrix components by expanded chondrocytes is therefore critical for successful cartilage repair.

KW - Humans

KW - Transforming Growth Factor beta pharmacology

KW - Image Processing, Computer-Assisted

KW - Cell Differentiation physiology

KW - Tissue Engineering methods

KW - Insulin-Like Growth Factor I pharmacology

KW - Bone Morphogenetic Protein 7 pharmacology

KW - Cartilage, Articular cytology

KW - Chondrocytes metabolism

KW - Collagen drug effects

KW - Collagen Type II metabolism

KW - Humans

KW - Transforming Growth Factor beta pharmacology

KW - Image Processing, Computer-Assisted

KW - Cell Differentiation physiology

KW - Tissue Engineering methods

KW - Insulin-Like Growth Factor I pharmacology

KW - Bone Morphogenetic Protein 7 pharmacology

KW - Cartilage, Articular cytology

KW - Chondrocytes metabolism

KW - Collagen drug effects

KW - Collagen Type II metabolism

M3 - SCORING: Zeitschriftenaufsatz

VL - 33

SP - 204

EP - 218

JO - INT J ARTIF ORGANS

JF - INT J ARTIF ORGANS

SN - 0391-3988

IS - 4

M1 - 4

ER -