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Estrogen synthesis in the hippocampus.

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Estrogen synthesis in the hippocampus. / Fester, Lars; Prange-Kiel, Janine; Jarry, Hubertus; Rune, Gabriele M.

in: CELL TISSUE RES, Jahrgang 345, Nr. 3, 3, 2011, S. 285-294.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Fester, L, Prange-Kiel, J, Jarry, H & Rune, GM 2011, 'Estrogen synthesis in the hippocampus.', CELL TISSUE RES, Jg. 345, Nr. 3, 3, S. 285-294. <http://www.ncbi.nlm.nih.gov/pubmed/21826442?dopt=Citation>

APA

Fester, L., Prange-Kiel, J., Jarry, H., & Rune, G. M. (2011). Estrogen synthesis in the hippocampus. CELL TISSUE RES, 345(3), 285-294. [3]. http://www.ncbi.nlm.nih.gov/pubmed/21826442?dopt=Citation

Vancouver

Fester L, Prange-Kiel J, Jarry H, Rune GM. Estrogen synthesis in the hippocampus. CELL TISSUE RES. 2011;345(3):285-294. 3.

Bibtex

@article{cf93e70ccfa5493982ba57c7fcab1e07,
title = "Estrogen synthesis in the hippocampus.",
abstract = "Estradiol plays essential roles in the modulation of synaptic plasticity and neuroprotection in males as well as in females, as has been shown particularly in the hippocampus. Although it has long been known that aromatase, the final enzyme in estrogen synthesis, is expressed in the hippocampus, a new paradigm emerged when it was shown that estradiol is actually synthesized de novo in this part of the brain. Increasing evidence indicates that hippocampus-derived estradiol plays a role in synaptic plasticity and neuroptrotection, rather than estradiol originating from the gonads. In recent years, a number of in vivo and in vitro studies have shown that hippocampus-derived estradiol substantially contributes to hippocampal function, in particular to structural synaptic plasticity.",
keywords = "Animals, Humans, Aromatase/metabolism, Estrogens/*biosynthesis, Hippocampus/cytology/enzymology/*metabolism, Neurons/cytology/metabolism, Animals, Humans, Aromatase/metabolism, Estrogens/*biosynthesis, Hippocampus/cytology/enzymology/*metabolism, Neurons/cytology/metabolism",
author = "Lars Fester and Janine Prange-Kiel and Hubertus Jarry and Rune, {Gabriele M.}",
year = "2011",
language = "English",
volume = "345",
pages = "285--294",
journal = "CELL TISSUE RES",
issn = "0302-766X",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Estrogen synthesis in the hippocampus.

AU - Fester, Lars

AU - Prange-Kiel, Janine

AU - Jarry, Hubertus

AU - Rune, Gabriele M.

PY - 2011

Y1 - 2011

N2 - Estradiol plays essential roles in the modulation of synaptic plasticity and neuroprotection in males as well as in females, as has been shown particularly in the hippocampus. Although it has long been known that aromatase, the final enzyme in estrogen synthesis, is expressed in the hippocampus, a new paradigm emerged when it was shown that estradiol is actually synthesized de novo in this part of the brain. Increasing evidence indicates that hippocampus-derived estradiol plays a role in synaptic plasticity and neuroptrotection, rather than estradiol originating from the gonads. In recent years, a number of in vivo and in vitro studies have shown that hippocampus-derived estradiol substantially contributes to hippocampal function, in particular to structural synaptic plasticity.

AB - Estradiol plays essential roles in the modulation of synaptic plasticity and neuroprotection in males as well as in females, as has been shown particularly in the hippocampus. Although it has long been known that aromatase, the final enzyme in estrogen synthesis, is expressed in the hippocampus, a new paradigm emerged when it was shown that estradiol is actually synthesized de novo in this part of the brain. Increasing evidence indicates that hippocampus-derived estradiol plays a role in synaptic plasticity and neuroptrotection, rather than estradiol originating from the gonads. In recent years, a number of in vivo and in vitro studies have shown that hippocampus-derived estradiol substantially contributes to hippocampal function, in particular to structural synaptic plasticity.

KW - Animals

KW - Humans

KW - Aromatase/metabolism

KW - Estrogens/biosynthesis

KW - Hippocampus/cytology/enzymology/metabolism

KW - Neurons/cytology/metabolism

KW - Animals

KW - Humans

KW - Aromatase/metabolism

KW - Estrogens/biosynthesis

KW - Hippocampus/cytology/enzymology/metabolism

KW - Neurons/cytology/metabolism

M3 - SCORING: Journal article

VL - 345

SP - 285

EP - 294

JO - CELL TISSUE RES

JF - CELL TISSUE RES

SN - 0302-766X

IS - 3

M1 - 3

ER -