Efficacy of two different CHX-containing desensitizers: a controlled double-blind study

S Drebenstedt; Antonia  Zapf; T Rödig; R F Mausberg; D Ziebolz

doi:10.2341/10-231-C

Efficacy of two different CHX-containing desensitizers

Standard

Efficacy of two different CHX-containing desensitizers : a controlled double-blind study. / Drebenstedt, S; Zapf, Antonia ; Rödig, T; Mausberg, R F; Ziebolz, D.

in: OPER DENT, Jahrgang 37, Nr. 2, 15.12.2011, S. 161-171.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Drebenstedt, S, Zapf, A, Rödig, T, Mausberg, RF & Ziebolz, D 2011, 'Efficacy of two different CHX-containing desensitizers: a controlled double-blind study', OPER DENT, Jg. 37, Nr. 2, S. 161-171. https://doi.org/10.2341/10-231-C

APA

Drebenstedt, S., Zapf, A., Rödig, T., Mausberg, R. F., & Ziebolz, D. (2011). Efficacy of two different CHX-containing desensitizers: a controlled double-blind study. OPER DENT, 37(2), 161-171. https://doi.org/10.2341/10-231-C

Vancouver

Drebenstedt S, Zapf A, Rödig T, Mausberg RF, Ziebolz D. Efficacy of two different CHX-containing desensitizers: a controlled double-blind study. OPER DENT. 2011 Dez 15;37(2):161-171. https://doi.org/10.2341/10-231-C

Bibtex

@article{c4c8be5878b24a628dc7a71108b624d3,

title = "Efficacy of two different CHX-containing desensitizers: a controlled double-blind study",

abstract = "The aim of this study was to compare the effectiveness and duration of action of the tooth desensitization agent Cervitec (C) vs that of the new Cervitec Plus (C+). In this monocentric, single-center, three-armed, controlled, double-blind study, 120 subjects were randomly assigned to one of three groups:group I received Cervitec Plus (C+), group II received Cervitec (C), and group III received placebo (P). Varnishes were applied after base-line determination of cervical dentin hyper-sensitivity using a pain score of one or higher.Re-evaluation was performed 1, 7, 30, and 90 days after application. Statistical evaluation was carried out using nonparametric statistics for relative effects and analysis of variance(ANOVA). Thirty days after application of Cand C+, all hypersensitivity decreased significantly in relation to baseline measurements(p<0.001), with no changes taking place in the placebo group. Significant differences were observed between C and C+ vs placebo(p<0.001), whereas no significant difference between C and C+ was seen after 30 days(p=0.840). After 90 days, the reduction in hypersensitivity with C+ was still significant compared with baseline measurements(p=0.001). However, C was not significantly different compared with baseline measurements (p=0.05). Analysis of all hypersensitive posterior teeth examined showed no significant difference between C and C+ after 90 days(p=0.362). For anterior teeth, the difference between C and C+ was significant (p=0.012).Both C and C+ reduce cervical tooth hypersensitivity, whereas C+ reduces hypersensitivity for a longer period of time.",

keywords = "Adult, Chlorhexidine, Dentin, Dentin Desensitizing Agents, Dentin Sensitivity, Double-Blind Method, Drug Combinations, Female, Follow-Up Studies, Humans, Male, Placebos, Polyvinyls, Thymol, Tooth Cervix, Treatment Outcome, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't",

author = "S Drebenstedt and Antonia Zapf and T R{\"o}dig and Mausberg, {R F} and D Ziebolz",

year = "2011",

month = dec,

day = "15",

doi = "10.2341/10-231-C",

language = "English",

volume = "37",

pages = "161--171",

journal = "OPER DENT",

issn = "0361-7734",

publisher = "Indiana University School of Dentistry",

number = "2",

}

RIS

TY - JOUR

T1 - Efficacy of two different CHX-containing desensitizers

T2 - a controlled double-blind study

AU - Drebenstedt, S

AU - Zapf, Antonia

AU - Rödig, T

AU - Mausberg, R F

AU - Ziebolz, D

PY - 2011/12/15

Y1 - 2011/12/15

N2 - The aim of this study was to compare the effectiveness and duration of action of the tooth desensitization agent Cervitec (C) vs that of the new Cervitec Plus (C+). In this monocentric, single-center, three-armed, controlled, double-blind study, 120 subjects were randomly assigned to one of three groups:group I received Cervitec Plus (C+), group II received Cervitec (C), and group III received placebo (P). Varnishes were applied after base-line determination of cervical dentin hyper-sensitivity using a pain score of one or higher.Re-evaluation was performed 1, 7, 30, and 90 days after application. Statistical evaluation was carried out using nonparametric statistics for relative effects and analysis of variance(ANOVA). Thirty days after application of Cand C+, all hypersensitivity decreased significantly in relation to baseline measurements(p<0.001), with no changes taking place in the placebo group. Significant differences were observed between C and C+ vs placebo(p<0.001), whereas no significant difference between C and C+ was seen after 30 days(p=0.840). After 90 days, the reduction in hypersensitivity with C+ was still significant compared with baseline measurements(p=0.001). However, C was not significantly different compared with baseline measurements (p=0.05). Analysis of all hypersensitive posterior teeth examined showed no significant difference between C and C+ after 90 days(p=0.362). For anterior teeth, the difference between C and C+ was significant (p=0.012).Both C and C+ reduce cervical tooth hypersensitivity, whereas C+ reduces hypersensitivity for a longer period of time.

AB - The aim of this study was to compare the effectiveness and duration of action of the tooth desensitization agent Cervitec (C) vs that of the new Cervitec Plus (C+). In this monocentric, single-center, three-armed, controlled, double-blind study, 120 subjects were randomly assigned to one of three groups:group I received Cervitec Plus (C+), group II received Cervitec (C), and group III received placebo (P). Varnishes were applied after base-line determination of cervical dentin hyper-sensitivity using a pain score of one or higher.Re-evaluation was performed 1, 7, 30, and 90 days after application. Statistical evaluation was carried out using nonparametric statistics for relative effects and analysis of variance(ANOVA). Thirty days after application of Cand C+, all hypersensitivity decreased significantly in relation to baseline measurements(p<0.001), with no changes taking place in the placebo group. Significant differences were observed between C and C+ vs placebo(p<0.001), whereas no significant difference between C and C+ was seen after 30 days(p=0.840). After 90 days, the reduction in hypersensitivity with C+ was still significant compared with baseline measurements(p=0.001). However, C was not significantly different compared with baseline measurements (p=0.05). Analysis of all hypersensitive posterior teeth examined showed no significant difference between C and C+ after 90 days(p=0.362). For anterior teeth, the difference between C and C+ was significant (p=0.012).Both C and C+ reduce cervical tooth hypersensitivity, whereas C+ reduces hypersensitivity for a longer period of time.

KW - Adult

KW - Chlorhexidine

KW - Dentin

KW - Dentin Desensitizing Agents

KW - Dentin Sensitivity

KW - Double-Blind Method

KW - Drug Combinations

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Placebos

KW - Polyvinyls

KW - Thymol

KW - Tooth Cervix

KW - Treatment Outcome

KW - Comparative Study

KW - Journal Article

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.2341/10-231-C

DO - 10.2341/10-231-C

M3 - SCORING: Journal article

C2 - 22166108

VL - 37

SP - 161

EP - 171

JO - OPER DENT

JF - OPER DENT

SN - 0361-7734

IS - 2

ER -