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Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke

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Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke. / Röther, J; Schellinger, P D; Gass, A; Siebler, M; Villringer, A; Fiebach, J B; Fiehler, Jens; Jansen, O; Kucinski, T; Schoder, V; Szabo, K; Junge-Hülsing, G J; Hennerici, M; Zeumer, Hermann; Sartor, K; Weiller, C; Hacke, W.

in: STROKE, Jahrgang 33, Nr. 10, 10, 2002, S. 2438-2445.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Röther, J, Schellinger, PD, Gass, A, Siebler, M, Villringer, A, Fiebach, JB, Fiehler, J, Jansen, O, Kucinski, T, Schoder, V, Szabo, K, Junge-Hülsing, GJ, Hennerici, M, Zeumer, H, Sartor, K, Weiller, C & Hacke, W 2002, 'Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke', STROKE, Jg. 33, Nr. 10, 10, S. 2438-2445. <http://www.ncbi.nlm.nih.gov/pubmed/12364735?dopt=Citation>

APA

Röther, J., Schellinger, P. D., Gass, A., Siebler, M., Villringer, A., Fiebach, J. B., Fiehler, J., Jansen, O., Kucinski, T., Schoder, V., Szabo, K., Junge-Hülsing, G. J., Hennerici, M., Zeumer, H., Sartor, K., Weiller, C., & Hacke, W. (2002). Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke. STROKE, 33(10), 2438-2445. [10]. http://www.ncbi.nlm.nih.gov/pubmed/12364735?dopt=Citation

Vancouver

Röther J, Schellinger PD, Gass A, Siebler M, Villringer A, Fiebach JB et al. Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke. STROKE. 2002;33(10):2438-2445. 10.

Bibtex

@article{da88330bf7d94dd085aed7b004ced087,
title = "Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke",
abstract = "BACKGROUND AND PURPOSE: The goals of this study were to examine MRI baseline characteristics of patients with acute ischemic stroke (AIS) and to study the influence of intravenous tissue plasminogen activator (tPA) on MR parameters and functional outcome using a multicenter approach. METHODS: In this open-label, nonrandomized study of AIS patients with suspected anterior circulation stroke, subjects received a multiparametric stroke MRI protocol (diffusion- and perfusion-weighted imaging and MR angiography) within 6 hours after symptom onset and on follow-up. Patients were treated either with tPA (thrombolysis group) or conservatively (no thrombolysis group). Functional outcome was assessed on day 90 (modified Rankin Score; mRS). RESULTS: We enrolled 139 AIS patients (no thrombolysis group, n=63; thrombolysis group, n=76). Patients treated with tPA were more severely affected (National Institutes of Health Stroke Scale score, 10 versus 13; P=0.002). Recanalization rates were higher in the thrombolysis group (Thrombolysis in Myocardial Infarction criteria 1 through 3 on day 1; 66.2% versus 32.7%; P",
author = "J R{\"o}ther and Schellinger, {P D} and A Gass and M Siebler and A Villringer and Fiebach, {J B} and Jens Fiehler and O Jansen and T Kucinski and V Schoder and K Szabo and Junge-H{\"u}lsing, {G J} and M Hennerici and Hermann Zeumer and K Sartor and C Weiller and W Hacke",
year = "2002",
language = "Deutsch",
volume = "33",
pages = "2438--2445",
journal = "STROKE",
issn = "0039-2499",
publisher = "Lippincott Williams and Wilkins",
number = "10",

}

RIS

TY - JOUR

T1 - Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke

AU - Röther, J

AU - Schellinger, P D

AU - Gass, A

AU - Siebler, M

AU - Villringer, A

AU - Fiebach, J B

AU - Fiehler, Jens

AU - Jansen, O

AU - Kucinski, T

AU - Schoder, V

AU - Szabo, K

AU - Junge-Hülsing, G J

AU - Hennerici, M

AU - Zeumer, Hermann

AU - Sartor, K

AU - Weiller, C

AU - Hacke, W

PY - 2002

Y1 - 2002

N2 - BACKGROUND AND PURPOSE: The goals of this study were to examine MRI baseline characteristics of patients with acute ischemic stroke (AIS) and to study the influence of intravenous tissue plasminogen activator (tPA) on MR parameters and functional outcome using a multicenter approach. METHODS: In this open-label, nonrandomized study of AIS patients with suspected anterior circulation stroke, subjects received a multiparametric stroke MRI protocol (diffusion- and perfusion-weighted imaging and MR angiography) within 6 hours after symptom onset and on follow-up. Patients were treated either with tPA (thrombolysis group) or conservatively (no thrombolysis group). Functional outcome was assessed on day 90 (modified Rankin Score; mRS). RESULTS: We enrolled 139 AIS patients (no thrombolysis group, n=63; thrombolysis group, n=76). Patients treated with tPA were more severely affected (National Institutes of Health Stroke Scale score, 10 versus 13; P=0.002). Recanalization rates were higher in the thrombolysis group (Thrombolysis in Myocardial Infarction criteria 1 through 3 on day 1; 66.2% versus 32.7%; P

AB - BACKGROUND AND PURPOSE: The goals of this study were to examine MRI baseline characteristics of patients with acute ischemic stroke (AIS) and to study the influence of intravenous tissue plasminogen activator (tPA) on MR parameters and functional outcome using a multicenter approach. METHODS: In this open-label, nonrandomized study of AIS patients with suspected anterior circulation stroke, subjects received a multiparametric stroke MRI protocol (diffusion- and perfusion-weighted imaging and MR angiography) within 6 hours after symptom onset and on follow-up. Patients were treated either with tPA (thrombolysis group) or conservatively (no thrombolysis group). Functional outcome was assessed on day 90 (modified Rankin Score; mRS). RESULTS: We enrolled 139 AIS patients (no thrombolysis group, n=63; thrombolysis group, n=76). Patients treated with tPA were more severely affected (National Institutes of Health Stroke Scale score, 10 versus 13; P=0.002). Recanalization rates were higher in the thrombolysis group (Thrombolysis in Myocardial Infarction criteria 1 through 3 on day 1; 66.2% versus 32.7%; P

M3 - SCORING: Zeitschriftenaufsatz

VL - 33

SP - 2438

EP - 2445

JO - STROKE

JF - STROKE

SN - 0039-2499

IS - 10

M1 - 10

ER -