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DNA Repair

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DNA Repair. / Borgmann, Kerstin; Köcher, Sabrina; Kriegs, Malte; Mansour Khalfallah, Wael Yassin; Parplys, Ann Christin; Rieckmann, Thorsten; Rothkamm, Kai.

Molecular Radio-Oncology. Hrsg. / Michael Baumann; Mechthild Krause; Nils Cordes. Band 198 1. Aufl. Berlin Heidelberg : Springer, 2016. S. 1-24 (Recent Results in Cancer Research).

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Harvard

Borgmann, K, Köcher, S, Kriegs, M, Mansour Khalfallah, WY, Parplys, AC, Rieckmann, T & Rothkamm, K 2016, DNA Repair. in M Baumann, M Krause & N Cordes (Hrsg.), Molecular Radio-Oncology. 1 Aufl., Bd. 198, Recent Results in Cancer Research, Springer, Berlin Heidelberg, S. 1-24.

APA

Borgmann, K., Köcher, S., Kriegs, M., Mansour Khalfallah, W. Y., Parplys, A. C., Rieckmann, T., & Rothkamm, K. (2016). DNA Repair. in M. Baumann, M. Krause, & N. Cordes (Hrsg.), Molecular Radio-Oncology (1 Aufl., Band 198, S. 1-24). (Recent Results in Cancer Research). Springer.

Vancouver

Borgmann K, Köcher S, Kriegs M, Mansour Khalfallah WY, Parplys AC, Rieckmann T et al. DNA Repair. in Baumann M, Krause M, Cordes N, Hrsg., Molecular Radio-Oncology. 1 Aufl. Band 198. Berlin Heidelberg: Springer. 2016. S. 1-24. (Recent Results in Cancer Research).

Bibtex

@inbook{687c0a194cbe41da885b1d58ff57d254,
title = "DNA Repair",
abstract = "Cellular chromosomal DNA is the principal target through which ionising radiation exerts it diverse biological effects. This chapter summarises the relevant DNA damage signalling and repair pathways used by normal and tumour cells in response to irradiation. Strategies for tumour radiosensitisation are reviewed which exploit tumour-specific DNA repair deficiencies or signalling pathway addictions, with a special focus on growth factor signalling, PARP, cancer stem cells, cell cycle checkpoints and DNA replication. This chapter concludes with a discussion of DNA repair-related candidate biomarkers of tumour response which are of crucial importance for implementing precision medicine in radiation oncology. ",
author = "Kerstin Borgmann and Sabrina K{\"o}cher and Malte Kriegs and {Mansour Khalfallah}, {Wael Yassin} and Parplys, {Ann Christin} and Thorsten Rieckmann and Kai Rothkamm",
year = "2016",
language = "English",
isbn = "978-3-662-49649-7",
volume = "198",
series = "Recent Results in Cancer Research",
publisher = "Springer",
pages = "1--24",
editor = "Michael Baumann and Mechthild Krause and Nils Cordes",
booktitle = "Molecular Radio-Oncology",
address = "Germany",
edition = "1",

}

RIS

TY - CHAP

T1 - DNA Repair

AU - Borgmann, Kerstin

AU - Köcher, Sabrina

AU - Kriegs, Malte

AU - Mansour Khalfallah, Wael Yassin

AU - Parplys, Ann Christin

AU - Rieckmann, Thorsten

AU - Rothkamm, Kai

PY - 2016

Y1 - 2016

N2 - Cellular chromosomal DNA is the principal target through which ionising radiation exerts it diverse biological effects. This chapter summarises the relevant DNA damage signalling and repair pathways used by normal and tumour cells in response to irradiation. Strategies for tumour radiosensitisation are reviewed which exploit tumour-specific DNA repair deficiencies or signalling pathway addictions, with a special focus on growth factor signalling, PARP, cancer stem cells, cell cycle checkpoints and DNA replication. This chapter concludes with a discussion of DNA repair-related candidate biomarkers of tumour response which are of crucial importance for implementing precision medicine in radiation oncology.

AB - Cellular chromosomal DNA is the principal target through which ionising radiation exerts it diverse biological effects. This chapter summarises the relevant DNA damage signalling and repair pathways used by normal and tumour cells in response to irradiation. Strategies for tumour radiosensitisation are reviewed which exploit tumour-specific DNA repair deficiencies or signalling pathway addictions, with a special focus on growth factor signalling, PARP, cancer stem cells, cell cycle checkpoints and DNA replication. This chapter concludes with a discussion of DNA repair-related candidate biomarkers of tumour response which are of crucial importance for implementing precision medicine in radiation oncology.

M3 - SCORING: Contribution to collected editions/anthologies

C2 - 27318679

SN - 978-3-662-49649-7

VL - 198

T3 - Recent Results in Cancer Research

SP - 1

EP - 24

BT - Molecular Radio-Oncology

A2 - Baumann, Michael

A2 - Krause, Mechthild

A2 - Cordes, Nils

PB - Springer

CY - Berlin Heidelberg

ER -