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DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases.

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DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases. / Padberg, B C; Lauritzen, I; Achilles, Eike-Gert; Holl, K; Bressel, M; Klöppel, G; Dralle, H; Schröder, S.

in: Virchows Arch A Pathol Anat Histopathol, Jahrgang 419, Nr. 3, 3, 1991, S. 167-170.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Padberg, BC, Lauritzen, I, Achilles, E-G, Holl, K, Bressel, M, Klöppel, G, Dralle, H & Schröder, S 1991, 'DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases.', Virchows Arch A Pathol Anat Histopathol, Jg. 419, Nr. 3, 3, S. 167-170. <http://www.ncbi.nlm.nih.gov/pubmed/1926757?dopt=Citation>

APA

Padberg, B. C., Lauritzen, I., Achilles, E-G., Holl, K., Bressel, M., Klöppel, G., Dralle, H., & Schröder, S. (1991). DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases. Virchows Arch A Pathol Anat Histopathol, 419(3), 167-170. [3]. http://www.ncbi.nlm.nih.gov/pubmed/1926757?dopt=Citation

Vancouver

Padberg BC, Lauritzen I, Achilles E-G, Holl K, Bressel M, Klöppel G et al. DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases. Virchows Arch A Pathol Anat Histopathol. 1991;419(3):167-170. 3.

Bibtex

@article{ed6120380f7948d5830bffc059dcfc90,
title = "DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases.",
abstract = "Surgical specimens of 66 adrenocortical tumours were investigated by conventional microscopy and DNA cytophotometry. Histologically, 50 neoplasms were classified as adenomas and 16 as carcinomas. In only 8 of the latter cases were distant metastases and/or a lethal outcome recorded. On single cell scanning cytophotometry either non-euploid or aneuploid DNA histograms were identified in 24 of 50 adenomas (48%) and in 14 of 16 carcinomas (88%). The two carcinomas exhibiting euploid DNA distributions fell into the group of 7 malignancies which are recurrence-free so far. From these findings it is concluded that DNA measurements have no diagnostic and only limited prognostic value in neoplasms of the adrenal cortex.",
author = "Padberg, {B C} and I Lauritzen and Eike-Gert Achilles and K Holl and M Bressel and G Kl{\"o}ppel and H Dralle and S Schr{\"o}der",
year = "1991",
language = "Deutsch",
volume = "419",
pages = "167--170",
journal = "VIRCHOWS ARCH",
issn = "0945-6317",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases.

AU - Padberg, B C

AU - Lauritzen, I

AU - Achilles, Eike-Gert

AU - Holl, K

AU - Bressel, M

AU - Klöppel, G

AU - Dralle, H

AU - Schröder, S

PY - 1991

Y1 - 1991

N2 - Surgical specimens of 66 adrenocortical tumours were investigated by conventional microscopy and DNA cytophotometry. Histologically, 50 neoplasms were classified as adenomas and 16 as carcinomas. In only 8 of the latter cases were distant metastases and/or a lethal outcome recorded. On single cell scanning cytophotometry either non-euploid or aneuploid DNA histograms were identified in 24 of 50 adenomas (48%) and in 14 of 16 carcinomas (88%). The two carcinomas exhibiting euploid DNA distributions fell into the group of 7 malignancies which are recurrence-free so far. From these findings it is concluded that DNA measurements have no diagnostic and only limited prognostic value in neoplasms of the adrenal cortex.

AB - Surgical specimens of 66 adrenocortical tumours were investigated by conventional microscopy and DNA cytophotometry. Histologically, 50 neoplasms were classified as adenomas and 16 as carcinomas. In only 8 of the latter cases were distant metastases and/or a lethal outcome recorded. On single cell scanning cytophotometry either non-euploid or aneuploid DNA histograms were identified in 24 of 50 adenomas (48%) and in 14 of 16 carcinomas (88%). The two carcinomas exhibiting euploid DNA distributions fell into the group of 7 malignancies which are recurrence-free so far. From these findings it is concluded that DNA measurements have no diagnostic and only limited prognostic value in neoplasms of the adrenal cortex.

M3 - SCORING: Zeitschriftenaufsatz

VL - 419

SP - 167

EP - 170

JO - VIRCHOWS ARCH

JF - VIRCHOWS ARCH

SN - 0945-6317

IS - 3

M1 - 3

ER -