Deficit syndrome in older schizophrenic patients.
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Deficit syndrome in older schizophrenic patients. / Harris, M J; Jeste, D V; Krüll, Andreas; Montague, J; Heaton, R K.
in: PSYCHIAT RES, Jahrgang 39, Nr. 3, 3, 1991, S. 285-292.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Deficit syndrome in older schizophrenic patients.
AU - Harris, M J
AU - Jeste, D V
AU - Krüll, Andreas
AU - Montague, J
AU - Heaton, R K
PY - 1991
Y1 - 1991
N2 - Previous studies have reported that a proportion of younger schizophrenic patients have the "deficit syndrome," with persistent "negative" symptoms not secondary to factors other than the disease process (e.g., depression). Yet, there is scant information on the deficit syndrome in older schizophrenic patients. We studied 46 schizophrenic patients over age 45. Seventeen met the criteria for the deficit syndrome as described by Carpenter et al. (1988), 20 were considered definite nondeficit patients, and 9 could not be classified. The deficit schizophrenic patients had a significantly higher total score on the Scale for the Assessment of Negative Symptoms but similar scores on scales for positive symptoms, depressive symptoms, and overall psychopathology as compared with nondeficit patients. The deficit patients also had a nonsignificantly greater impairment on the Halstead-Reitan Battery. One notable difference between our results and those of Carpenter et al. was in the prevalence of deficit syndrome. We found the prevalence (37%) to be significantly higher than that reported in younger patients (15%). Pending confirmation using larger sample sizes, the increased frequency of the deficit syndrome in our study could possibly be attributed to aging or a longer duration of illness in our subjects.
AB - Previous studies have reported that a proportion of younger schizophrenic patients have the "deficit syndrome," with persistent "negative" symptoms not secondary to factors other than the disease process (e.g., depression). Yet, there is scant information on the deficit syndrome in older schizophrenic patients. We studied 46 schizophrenic patients over age 45. Seventeen met the criteria for the deficit syndrome as described by Carpenter et al. (1988), 20 were considered definite nondeficit patients, and 9 could not be classified. The deficit schizophrenic patients had a significantly higher total score on the Scale for the Assessment of Negative Symptoms but similar scores on scales for positive symptoms, depressive symptoms, and overall psychopathology as compared with nondeficit patients. The deficit patients also had a nonsignificantly greater impairment on the Halstead-Reitan Battery. One notable difference between our results and those of Carpenter et al. was in the prevalence of deficit syndrome. We found the prevalence (37%) to be significantly higher than that reported in younger patients (15%). Pending confirmation using larger sample sizes, the increased frequency of the deficit syndrome in our study could possibly be attributed to aging or a longer duration of illness in our subjects.
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Chronic Disease
KW - Syndrome
KW - Neuropsychological Tests
KW - Schizophrenic Psychology
KW - Dementia/diagnosis/psychology
KW - Schizophrenia/diagnosis
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Chronic Disease
KW - Syndrome
KW - Neuropsychological Tests
KW - Schizophrenic Psychology
KW - Dementia/diagnosis/psychology
KW - Schizophrenia/diagnosis
M3 - SCORING: Journal article
VL - 39
SP - 285
EP - 292
JO - PSYCHIAT RES
JF - PSYCHIAT RES
SN - 0165-1781
IS - 3
M1 - 3
ER -