Death begets a new beginning

Lidia Bosurgi; Lindsey D Hughes; Carla V Rothlin; Sourav Ghosh

doi:10.1111/imr.12585

Death begets a new beginning

Standard

Death begets a new beginning. / Bosurgi, Lidia; Hughes, Lindsey D; Rothlin, Carla V; Ghosh, Sourav.

in: IMMUNOL REV, Jahrgang 280, Nr. 1, 11.2017, S. 8-25.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Bosurgi, L, Hughes, LD, Rothlin, CV & Ghosh, S 2017, 'Death begets a new beginning', IMMUNOL REV, Jg. 280, Nr. 1, S. 8-25. https://doi.org/10.1111/imr.12585

APA

Bosurgi, L., Hughes, L. D., Rothlin, C. V., & Ghosh, S. (2017). Death begets a new beginning. IMMUNOL REV, 280(1), 8-25. https://doi.org/10.1111/imr.12585

Vancouver

Bosurgi L, Hughes LD, Rothlin CV, Ghosh S. Death begets a new beginning. IMMUNOL REV. 2017 Nov;280(1):8-25. https://doi.org/10.1111/imr.12585

Bibtex

@article{b6b3eabfad3343e18cea74342476c3b5,

title = "Death begets a new beginning",

abstract = "Cell death is a perpetual feature of tissue microenvironments; each day under homeostatic conditions, billions of cells die and must be swiftly cleared by phagocytes. However, cell death is not limited to this natural turnover-apoptotic cell death can be induced by infection, inflammation, or severe tissue injury. Phagocytosis of apoptotic cells is thus coupled to specific functions, from the induction of growth factors that can stimulate the replacement of dead cells to the promotion of tissue repair or tissue remodeling in the affected site. In this review, we outline the mechanisms by which phagocytes sense apoptotic cell death and discuss how phagocytosis is integrated with environmental cues to drive appropriate responses.",

keywords = "Journal Article, Review",

author = "Lidia Bosurgi and Hughes, {Lindsey D} and Rothlin, {Carla V} and Sourav Ghosh",

note = "{\textcopyright} 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",

year = "2017",

month = nov,

doi = "10.1111/imr.12585",

language = "English",

volume = "280",

pages = "8--25",

journal = "IMMUNOL REV",

issn = "0105-2896",

publisher = "Wiley-Blackwell",

number = "1",

}

RIS

TY - JOUR

T1 - Death begets a new beginning

AU - Bosurgi, Lidia

AU - Hughes, Lindsey D

AU - Rothlin, Carla V

AU - Ghosh, Sourav

PY - 2017/11

Y1 - 2017/11

N2 - Cell death is a perpetual feature of tissue microenvironments; each day under homeostatic conditions, billions of cells die and must be swiftly cleared by phagocytes. However, cell death is not limited to this natural turnover-apoptotic cell death can be induced by infection, inflammation, or severe tissue injury. Phagocytosis of apoptotic cells is thus coupled to specific functions, from the induction of growth factors that can stimulate the replacement of dead cells to the promotion of tissue repair or tissue remodeling in the affected site. In this review, we outline the mechanisms by which phagocytes sense apoptotic cell death and discuss how phagocytosis is integrated with environmental cues to drive appropriate responses.

AB - Cell death is a perpetual feature of tissue microenvironments; each day under homeostatic conditions, billions of cells die and must be swiftly cleared by phagocytes. However, cell death is not limited to this natural turnover-apoptotic cell death can be induced by infection, inflammation, or severe tissue injury. Phagocytosis of apoptotic cells is thus coupled to specific functions, from the induction of growth factors that can stimulate the replacement of dead cells to the promotion of tissue repair or tissue remodeling in the affected site. In this review, we outline the mechanisms by which phagocytes sense apoptotic cell death and discuss how phagocytosis is integrated with environmental cues to drive appropriate responses.

KW - Journal Article

KW - Review

U2 - 10.1111/imr.12585

DO - 10.1111/imr.12585

M3 - SCORING: Review article

C2 - 29027219

VL - 280

SP - 8

EP - 25

JO - IMMUNOL REV

JF - IMMUNOL REV

SN - 0105-2896

IS - 1

ER -