C-type natriuretic peptide exerts effects opposing those of atrial natriuretic peptide on anxiety-related behaviour in rats.

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C-type natriuretic peptide exerts effects opposing those of atrial natriuretic peptide on anxiety-related behaviour in rats. / Montkowski, A; Jahn, Holger; Ströhle, A; Poettig, M; Holsboer, F; Wiedemann, Klaus.

in: BRAIN RES, Jahrgang 792, Nr. 2, 2, 1998, S. 358-360.

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@article{a07eadb4e5544c5b857744f98debc9ca,
title = "C-type natriuretic peptide exerts effects opposing those of atrial natriuretic peptide on anxiety-related behaviour in rats.",
abstract = "As evidence exists that C-type natriuretic peptide (CNP) exerts effects opposing those of atrial natriuretic peptide (ANP), we studied the behavioural properties of CNP after central infusion in rats by their performance in the elevated plus maze. Doses of 0.5 microg and 5 microg i.c.v. had distinct anxiogenic properties. Our data suggest opposing effects of CNP and ANP on anxiety-related behaviour in rats, which appear to be mediated via different receptor occupation and brain regions by a corticotropin-releasing hormone (CRH)-dependent mechanism.",
author = "A Montkowski and Holger Jahn and A Str{\"o}hle and M Poettig and F Holsboer and Klaus Wiedemann",
year = "1998",
language = "Deutsch",
volume = "792",
pages = "358--360",
journal = "BRAIN RES",
issn = "0006-8993",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - C-type natriuretic peptide exerts effects opposing those of atrial natriuretic peptide on anxiety-related behaviour in rats.

AU - Montkowski, A

AU - Jahn, Holger

AU - Ströhle, A

AU - Poettig, M

AU - Holsboer, F

AU - Wiedemann, Klaus

PY - 1998

Y1 - 1998

N2 - As evidence exists that C-type natriuretic peptide (CNP) exerts effects opposing those of atrial natriuretic peptide (ANP), we studied the behavioural properties of CNP after central infusion in rats by their performance in the elevated plus maze. Doses of 0.5 microg and 5 microg i.c.v. had distinct anxiogenic properties. Our data suggest opposing effects of CNP and ANP on anxiety-related behaviour in rats, which appear to be mediated via different receptor occupation and brain regions by a corticotropin-releasing hormone (CRH)-dependent mechanism.

AB - As evidence exists that C-type natriuretic peptide (CNP) exerts effects opposing those of atrial natriuretic peptide (ANP), we studied the behavioural properties of CNP after central infusion in rats by their performance in the elevated plus maze. Doses of 0.5 microg and 5 microg i.c.v. had distinct anxiogenic properties. Our data suggest opposing effects of CNP and ANP on anxiety-related behaviour in rats, which appear to be mediated via different receptor occupation and brain regions by a corticotropin-releasing hormone (CRH)-dependent mechanism.

M3 - SCORING: Zeitschriftenaufsatz

VL - 792

SP - 358

EP - 360

JO - BRAIN RES

JF - BRAIN RES

SN - 0006-8993

IS - 2

M1 - 2

ER -