PortalPublikationenC-reactive protein is not a screening tool for late peripros...

C-reactive protein is not a screening tool for late periprosthetic joint infection

Standard

C-reactive protein is not a screening tool for late periprosthetic joint infection. / Fink, Bernd; Schlumberger, Michael; Beyersdorff, Julian; Schuster, Philipp.

in: J ORTHOP TRAUMATOL, Jahrgang 21, Nr. 1, 24.02.2020, S. 2.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Fink, B, Schlumberger, M, Beyersdorff, J & Schuster, P 2020, 'C-reactive protein is not a screening tool for late periprosthetic joint infection', J ORTHOP TRAUMATOL, Jg. 21, Nr. 1, S. 2. https://doi.org/10.1186/s10195-020-0542-2

APA

Fink, B., Schlumberger, M., Beyersdorff, J., & Schuster, P. (2020). C-reactive protein is not a screening tool for late periprosthetic joint infection. J ORTHOP TRAUMATOL, 21(1), 2. https://doi.org/10.1186/s10195-020-0542-2

Vancouver

Fink B, Schlumberger M, Beyersdorff J, Schuster P. C-reactive protein is not a screening tool for late periprosthetic joint infection. J ORTHOP TRAUMATOL. 2020 Feb 24;21(1):2. https://doi.org/10.1186/s10195-020-0542-2

Bibtex

@article{8ece60a91e994a3fbeff356567164791,
title = "C-reactive protein is not a screening tool for late periprosthetic joint infection",
abstract = "BACKGROUND: Preoperative diagnosis of periprosthetic joint infection (PJI) is important because of the therapeutic consequences. The aim of the present study is to investigate whether the serum C-reactive protein (CRP) level can be used as a screening tool for late PJI.MATERIALS AND METHODS: A cohort of 390 patients with revision surgery of total hip prostheses (200) or total knee prostheses (190) was assessed for late PJI by determining CRP serum level and performing preoperative aspiration with cultivation and intraoperative tissue analyses with cultivation and histologic examination, using the Musculoskeletal Infection Society (MSIS) and International Consensus Meeting (ICM) criteria.RESULTS: A total of 180 joints were rated as PJI (prevalence 46%). Of these, 42.8% (77) showed a CRP level below 10 mg/L and 28.3% (51) showed a normal CRP level of less than 5 mg/L. The 76.9% of the cases with slow-growing bacteria showed a CRP level below 10 mg/L, and 61.5% showed a normal CRP level.CONCLUSIONS: Serum CRP level should not be used as a screening tool to rule out late PJI.LEVEL OF EVIDENCE: Level 2 (diagnostic study).",
keywords = "Adult, Aged, Aged, 80 and over, Arthritis, Infectious/blood, Arthroplasty, Replacement, Hip/adverse effects, Arthroplasty, Replacement, Knee/adverse effects, Biomarkers/blood, C-Reactive Protein/metabolism, Female, Humans, Knee Prosthesis/adverse effects, Male, Middle Aged, Prosthesis-Related Infections/blood",
author = "Bernd Fink and Michael Schlumberger and Julian Beyersdorff and Philipp Schuster",
year = "2020",
month = feb,
day = "24",
doi = "10.1186/s10195-020-0542-2",
language = "English",
volume = "21",
pages = "2",
journal = "J ORTHOP TRAUMATOL",
issn = "1590-9921",
publisher = "Springer-Verlag Italia",
number = "1",

}

RIS

TY - JOUR

T1 - C-reactive protein is not a screening tool for late periprosthetic joint infection

AU - Fink, Bernd

AU - Schlumberger, Michael

AU - Beyersdorff, Julian

AU - Schuster, Philipp

PY - 2020/2/24

Y1 - 2020/2/24

N2 - BACKGROUND: Preoperative diagnosis of periprosthetic joint infection (PJI) is important because of the therapeutic consequences. The aim of the present study is to investigate whether the serum C-reactive protein (CRP) level can be used as a screening tool for late PJI.MATERIALS AND METHODS: A cohort of 390 patients with revision surgery of total hip prostheses (200) or total knee prostheses (190) was assessed for late PJI by determining CRP serum level and performing preoperative aspiration with cultivation and intraoperative tissue analyses with cultivation and histologic examination, using the Musculoskeletal Infection Society (MSIS) and International Consensus Meeting (ICM) criteria.RESULTS: A total of 180 joints were rated as PJI (prevalence 46%). Of these, 42.8% (77) showed a CRP level below 10 mg/L and 28.3% (51) showed a normal CRP level of less than 5 mg/L. The 76.9% of the cases with slow-growing bacteria showed a CRP level below 10 mg/L, and 61.5% showed a normal CRP level.CONCLUSIONS: Serum CRP level should not be used as a screening tool to rule out late PJI.LEVEL OF EVIDENCE: Level 2 (diagnostic study).

AB - BACKGROUND: Preoperative diagnosis of periprosthetic joint infection (PJI) is important because of the therapeutic consequences. The aim of the present study is to investigate whether the serum C-reactive protein (CRP) level can be used as a screening tool for late PJI.MATERIALS AND METHODS: A cohort of 390 patients with revision surgery of total hip prostheses (200) or total knee prostheses (190) was assessed for late PJI by determining CRP serum level and performing preoperative aspiration with cultivation and intraoperative tissue analyses with cultivation and histologic examination, using the Musculoskeletal Infection Society (MSIS) and International Consensus Meeting (ICM) criteria.RESULTS: A total of 180 joints were rated as PJI (prevalence 46%). Of these, 42.8% (77) showed a CRP level below 10 mg/L and 28.3% (51) showed a normal CRP level of less than 5 mg/L. The 76.9% of the cases with slow-growing bacteria showed a CRP level below 10 mg/L, and 61.5% showed a normal CRP level.CONCLUSIONS: Serum CRP level should not be used as a screening tool to rule out late PJI.LEVEL OF EVIDENCE: Level 2 (diagnostic study).

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Arthritis, Infectious/blood

KW - Arthroplasty, Replacement, Hip/adverse effects

KW - Arthroplasty, Replacement, Knee/adverse effects

KW - Biomarkers/blood

KW - C-Reactive Protein/metabolism

KW - Female

KW - Humans

KW - Knee Prosthesis/adverse effects

KW - Male

KW - Middle Aged

KW - Prosthesis-Related Infections/blood

U2 - 10.1186/s10195-020-0542-2

DO - 10.1186/s10195-020-0542-2

M3 - SCORING: Journal article

C2 - 32095896

VL - 21

SP - 2

JO - J ORTHOP TRAUMATOL

JF - J ORTHOP TRAUMATOL

SN - 1590-9921

IS - 1

ER -