Computerized brain tomography measures compared with spontaneous and suppressed plasma cortisol levels in major depression.
Standard
Computerized brain tomography measures compared with spontaneous and suppressed plasma cortisol levels in major depression. / Schlegel, S; von Bardeleben, U; Wiedemann, Klaus; Frommberger, U; Holsboer, F.
in: PSYCHONEUROENDOCRINO, Jahrgang 14, Nr. 3, 3, 1989, S. 209-216.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Computerized brain tomography measures compared with spontaneous and suppressed plasma cortisol levels in major depression.
AU - Schlegel, S
AU - von Bardeleben, U
AU - Wiedemann, Klaus
AU - Frommberger, U
AU - Holsboer, F
PY - 1989
Y1 - 1989
N2 - We determined brain density and ventricular measurements with computerized tomography (CT) in 33 depressed patients and compared the results with basal plasma cortisol and its suppressibility by dexamethasone. Mean plasma cortisol was positively related to elevated ventricular brain ratio (VBR). No association could be found between dexamethasone suppression test (DST) status and VBR or any other CT parameter. Elevated plasma cortisol levels and increased VBRs were positively correlated with total scores on the Brief Psychiatric Rating Scale, the Global Assessment Scale and the Bech-Rafaelsen Melancholia Scale, but they were not significantly correlated with total score on the Hamilton Anxiety Scale.
AB - We determined brain density and ventricular measurements with computerized tomography (CT) in 33 depressed patients and compared the results with basal plasma cortisol and its suppressibility by dexamethasone. Mean plasma cortisol was positively related to elevated ventricular brain ratio (VBR). No association could be found between dexamethasone suppression test (DST) status and VBR or any other CT parameter. Elevated plasma cortisol levels and increased VBRs were positively correlated with total scores on the Brief Psychiatric Rating Scale, the Global Assessment Scale and the Bech-Rafaelsen Melancholia Scale, but they were not significantly correlated with total score on the Hamilton Anxiety Scale.
M3 - SCORING: Zeitschriftenaufsatz
VL - 14
SP - 209
EP - 216
JO - PSYCHONEUROENDOCRINO
JF - PSYCHONEUROENDOCRINO
SN - 0306-4530
IS - 3
M1 - 3
ER -